Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation

2009 ◽  
Vol 139 (3) ◽  
pp. 203-210 ◽  
Author(s):  
Jiří Holátko ◽  
Veronika Elišáková ◽  
Marek Prouza ◽  
Miroslav Sobotka ◽  
Jan Nešvera ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Corynebacterium Glutamicum ◽  
Promoter Activity ◽  
Biosynthesis Pathway ◽  
Valine Biosynthesis

Development of bio-chemical route to C5 plasticizer synthesis using glutaric acid produced by metabolically engineered Corynebacterium glutamicum

2022 ◽  
Author(s):  
Yu Jung Sohn ◽  
Minsoo Kang ◽  
Mi-Hee Ryu ◽  
Siseon Lee ◽  
Kyoung Hee Kang ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Pseudomonas Putida ◽  
Corynebacterium Glutamicum ◽  
Glutaric Acid ◽  
Biosynthesis Pathway ◽  
Acid Biosynthesis ◽  
Chemical Route

Corynebacterium glutamicum was engineered to produce glutaric acid by metabolic engineering approaches starting from the heterologous introduction of glutaric acid biosynthesis pathway by the expression of Pseudomonas putida davT, davD,...

USAGE OF TRANSCRIPTIONAL REGULATOR LRP BASED BIOSENSOR FOR RESEARCH OF VALINE BIOSYNTHESIS PATHWAYS IN CORYNEBACTERIUM GLUTAMICUM CELLS

2021 ◽  
Vol 1 (19) ◽  
pp. 318-320
Author(s):  
D.D. Derbikov ◽  
A.S. Yanenko
Keyword(s):  
Corynebacterium Glutamicum ◽  
Protein Gene ◽  
Transcriptional Regulator ◽  
Valine Biosynthesis ◽  
Fluorescence Protein ◽  
Gene Promotor

The biosensor construction based on Lrp gene was obtained, what contains a fluorescence protein gene under control of BrnFE gene promotor. It was displayed that the fluorescence of Corynebacterium glutamicum cells carrying the biosensor correlates with the production of valine, and with its help it is possible to study the biosynthesis of valine.

Metabolic Engineering of Lysine Producing Corynebacterium glutamicum Strains

2020 ◽  
Vol 54 (2) ◽  
pp. 137-146
Author(s):  
G. S. Andriiash ◽  
O. S. Sekan ◽  
O. O. Tigunova ◽  
Ya. B. Blume ◽  
S. M. Shulga
Keyword(s):  
Metabolic Engineering ◽  
Corynebacterium Glutamicum
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