Relapsing polychondritis and ankylosing spondylitis in the same patient

2006 ◽  
Vol 73 (4) ◽  
pp. 482-484 ◽  
Author(s):  
Rachid Bahiri ◽  
Fatiha Bzami ◽  
Karima Benbouazza ◽  
Bouchra Saoud ◽  
Najia Hajjaj-Hassouni
Keyword(s):  
Ankylosing Spondylitis ◽  
Relapsing Polychondritis

scholarly journals Relapsing Polychondritis in a Patient with Ankylosing Spondylitis Using Etanercept

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Valderilio Feijó Azevedo ◽  
Natalia Bassalobre Galli ◽  
Alais Daiane Fadini Kleinfelder ◽  
Julia Farabolini D’Ippolito ◽  
Andressa Gulin Tolentino ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Autoimmune Disease ◽  
Tumor Necrosis ◽  
Biological Therapy ◽  
Relapsing Polychondritis ◽  
Tracheobronchial Tree ◽  
Substantial Improvement ◽  
Autoantibody Production ◽  
Cartilaginous Tissues ◽  
Necrosis Factor

Relapsing polychondritis (RP) is an autoimmune disease characterized by recurrent episodes of inflammation and progressive destruction of cartilaginous tissues, especially of the ears, nose, joints, and tracheobronchial tree. Its etiology is not well understood, but some studies have linked its pathophysiology with autoimmune disease and autoantibody production. We described a case of a 46-year-old male patient with ankylosing spondylitis who developed RP after the use of etanercept. Few similar cases have been described in the literature. However, they show a possible association between the use of biological inhibitors of tumor necrosis factor (anti-TNFα), which potentially produces autoantibodies, and the development of RP. The treatment was based on data in the literature and included the cessation of biological therapy and the addition of corticosteroids with substantial improvement.

A Case of Relapsing Polychondritis Associated with Ankylosing Spondylitis

2015 ◽  
Vol 22 (1) ◽  
pp. 56
Author(s):  
Nam Hee Yi ◽  
Seung Woon Park ◽  
In Seong Park ◽  
Chi Hwan Park ◽  
Choong Won Lee
Keyword(s):  
Ankylosing Spondylitis ◽  
Relapsing Polychondritis

scholarly journals Relapsing Polychondritis following Treatment with Secukinumab for Ankylosing Spondylitis: Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Alexander Zheutlin ◽  
Elena Schiopu
Keyword(s):  
Case Report ◽  
Ankylosing Spondylitis ◽  
Tumor Necrosis ◽  
Case Reports ◽  
Relapsing Polychondritis ◽  
Autoimmune Disorder ◽  
Review Of The Literature ◽  
Interleukin 17A ◽  
First Case ◽  
Physician Awareness

Relapsing polychondritis (RP) is an autoimmune disorder that often occurs concomitantly with other autoimmune diseases, though RP has been infrequently associated with ankylosing spondylitis (AS). There is a small, but growing, body of the literature demonstrating case reports describing RP secondary to AS in patients treated with tumor necrosis alpha inhibitors (TNFi’s). We present the first case in which RP developed in AS while treated with an interleukin 17A inhibitor (IL-17Ai), secukinumab. With this case report, we hope to raise physician awareness of the possible autoimmune disorders that may arise subsequent to novel immunomodulation therapies, particularly that RP may develop subsequent to inhibition of IL-17A.

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