Relapsing Polychondritis following Treatment with Secukinumab for Ankylosing Spondylitis: Case Report and Review of the Literature

Relapsing polychondritis (RP) is an autoimmune disorder that often occurs concomitantly with other autoimmune diseases, though RP has been infrequently associated with ankylosing spondylitis (AS). There is a small, but growing, body of the literature demonstrating case reports describing RP secondary to AS in patients treated with tumor necrosis alpha inhibitors (TNFi’s). We present the first case in which RP developed in AS while treated with an interleukin 17A inhibitor (IL-17Ai), secukinumab. With this case report, we hope to raise physician awareness of the possible autoimmune disorders that may arise subsequent to novel immunomodulation therapies, particularly that RP may develop subsequent to inhibition of IL-17A.

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Multiple Extrauterine Adenomyomas Presenting in Upper Abdomen and Pelvis: A Case Report and Brief Review of the Literature

Case Reports in Obstetrics and Gynecology ◽

10.1155/2012/565901 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3

Author(s):

Mana Moghadamfalahi ◽

Daniel S. Metzinger

Keyword(s):

Smooth Muscle ◽

Case Report ◽

Unusual Case ◽

Case Reports ◽

Abdominal Mass ◽

Benign Tumors ◽

Review Of The Literature ◽

First Case ◽

Upper Abdominal ◽

Upper Abdomen

Adenomyomas are benign tumors composed of smooth muscle and endometrial tissue. These tumors usually arise from the myometrium. Extrauterine adenomyomas are rare with only a few case reports available in the literature. Here, we report an unusual case of multiple adenomyomas in a 39-year-old woman six years after hysterectomy for multiple leiomyomata. To the best of our knowledge, this is the first case of extrauterine adenomyoma presenting as an upper abdominal mass.

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Efficacy of tocilizumab for psychiatric symptoms associated with relapsing polychondritis: the first case report and review of the literature

Rheumatology International ◽

10.1007/s00296-016-3509-0 ◽

2016 ◽

Vol 36 (8) ◽

pp. 1185-1189 ◽

Cited By ~ 3

Author(s):

Lijun Liu ◽

Shengyun Liu ◽

Wenjuan Guan ◽

Lei Zhang

Keyword(s):

Case Report ◽

Psychiatric Symptoms ◽

Relapsing Polychondritis ◽

Review Of The Literature ◽

First Case

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Neonatal airway lesions: our experience and a review of the literature

The Journal of Laryngology & Otology ◽

10.1017/s002221511200254x ◽

2012 ◽

Vol 127 (1) ◽

pp. 80-83 ◽

Cited By ~ 3

Author(s):

V Rangachari ◽

R Aggarwal ◽

A Jain ◽

M C Kapoor

Keyword(s):

Case Report ◽

Multidisciplinary Team ◽

Congenital Anomalies ◽

Case Reports ◽

High Index ◽

Institutional Setting ◽

Review Of The Literature ◽

First Case ◽

High Index Of Suspicion

AbstractObjectives:This paper reports on two rare cases of neonatal airway lesions with differing aetiology that were successfully managed by surgery, and provides a review of the literature on neonatal stridor and airway lesions.Case reports:In the first case report, a newborn presented with a nasopharyngeal teratoma. In the second case report, a newborn presented with a congenital laryngeal saccular cyst. Difficulties in the diagnosis of these lesions, and surgical and anaesthetic challenges in their management are discussed.Conclusion:Every case of neonatal airway distress must be evaluated and the cause of stridor needs to be established. It is important that rare lesions such as teratomas and laryngeal cysts are not overlooked; a high index of suspicion for these congenital anomalies is necessary. These airway lesions should be managed in an institutional setting by a multidisciplinary team.

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Proteus syndrome in pregnancy: A case report

Obstetric Medicine ◽

10.1177/1753495x20970791 ◽

2020 ◽

pp. 1753495X2097079

Author(s):

Niccole Ranaei-Zamani ◽

Mandeep K Kaler ◽

Rehan Khan

Keyword(s):

Case Report ◽

Case Reports ◽

Proteus Syndrome ◽

Cutaneous Lesions ◽

Genetic Syndrome ◽

Skeletal Tissue ◽

First Case ◽

Large Teaching Hospital ◽

Clinical Presentations ◽

In Pregnancy

Proteus syndrome is a rare, multi-system, genetic syndrome characterised by atypical and excessive growth of skeletal tissue. Clinical presentations include abnormal musculoskeletal growth and cutaneous lesions. Due to its rarity, there have been a limited number of published case reports of Proteus syndrome. This is the first case report on the management of Proteus syndrome in pregnancy. We present the case of a pregnant woman with Proteus syndrome in her first pregnancy in a large teaching hospital and discuss the considerations and challenges faced in her antenatal, intrapartum and postnatal care.

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Intraperitoneal ampicillin treatment for peritoneal dialysis- related peritonitis with Listeria monocytogenes – a case report

BMC Nephrology ◽

10.1186/s12882-020-02068-1 ◽

2020 ◽

Vol 21 (1) ◽

Author(s):

Kristina Boss ◽

Ina Wiegard-Szramek ◽

Jan Dziobaka ◽

Andreas Kribben ◽

Sebastian Dolff

Keyword(s):

Peritoneal Dialysis ◽

Case Report ◽

Listeria Monocytogenes ◽

Case Reports ◽

Chronic Kidney Disease Stage ◽

Disease Stage ◽

Serum Concentrations ◽

Duration Of Treatment ◽

First Case ◽

Listeria Infection

Abstract Background Peritoneal dialysis (PD)-related peritonitis is a rare but serious complication and is associated with increased morbidity and mortality rates. It is most commonly caused by Staphylococcus aureus or Staphylococcus epidermidis, but infection with Listeria monocytogenes may also occur. Recommendations for antibiotic treatment of a Listeria infection are currently based on a small number of case reports and suggest the administration of ampicillin. But unlike vancomycin or gentamicin, for ampicillin the route of application, the dosage, and the duration of treatment have not yet been established. We report a case in which PD-associated peritonitis due to Listeria infection was treated with ampicillin administered intravenously and intraperitoneally, separately and in combination. Case presentation A 72-year-old man with chronic kidney disease stage 5 dialysis (CKDG5D) secondary to hypertension and diabetes was hospitalised in April 2020 because of PD-related peritonitis caused by a Listeria infection. In accordance with the results of resistance tests, the patient was treated with intravenous ampicillin at a dosage of 6 g twice daily. After initial treatment the leukocyte count in the PD effluent had decreased substantially, but it was permanently reduced only with the addition of intraperitoneal ampicillin (4 g daily). Efficient serum concentrations of ampicillin were determined for both routes of administration, intravenous and intraperitoneal. Conclusion This is the first case report demonstrating that PD-related peritonitis due to Listeria monocytogenes infection can be treated with intraperitoneal ampicillin and monitored by the determination of peripheral serum concentrations of ampicillin.

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Osteoblastoma of the clavicle at the site of a previous fracture—first case report and review of the literature

Skeletal Radiology ◽

10.1007/s00256-019-03197-x ◽

2019 ◽

Vol 48 (10) ◽

pp. 1623-1628

Author(s):

Adriana C. Moreira ◽

David I. Suster ◽

Sterling Ellis Eide ◽

Daniel I. Rosenthal ◽

Connie Y. Chang

Keyword(s):

Case Report ◽

Review Of The Literature ◽

Previous Fracture ◽

First Case

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Hemophagocytic Lymphohistiocytosis Complicating Erythroleukemia in a Child with Monosomy 7: A Case Report and Review of the Literature

Case Reports in Hematology ◽

10.1155/2013/581073 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3

Author(s):

Samin Alavi ◽

Maryam Ebadi ◽

Alireza Jenabzadeh ◽

M. T. Arzanian ◽

Sh. Shamsian

Keyword(s):

Bone Marrow ◽

Case Report ◽

Hemophagocytic Lymphohistiocytosis ◽

Chromosomal Abnormalities ◽

Bone Marrow Aspiration ◽

Review Of The Literature ◽

Monosomy 7 ◽

Persistent Fever ◽

First Case ◽

Erythroid Precursors

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.

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Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

Allergy & Rhinology ◽

10.2500/ar.2015.6.0127 ◽

2015 ◽

Vol 6 (2) ◽

pp. ar.2015.6.0127 ◽

Cited By ~ 7

Author(s):

Juliette O. Flam ◽

Christopher D. Brook ◽

Rachel Sobel ◽

John C. Lee ◽

Michael P. Platt

Keyword(s):

Case Report ◽

Physical Examination ◽

Nasal Cavity ◽

Surgical Excision ◽

Myoepithelial Carcinoma ◽

Review Of The Literature ◽

Nasal Symptoms ◽

First Case ◽

Nasal Tumor ◽

Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

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