Alkaline cation-exchange chromatography for the reduction of aggregate and a mis-formed disulfide variant in a bispecific antibody purification process

2015 ◽  
Vol 975 ◽  
pp. 1-8 ◽  
Author(s):  
Troii Hall ◽  
Joseph J. Wilson ◽  
Tammy J. Brownlee ◽  
James R. Swartling ◽  
Sarah E. Langan ◽  
...  
Keyword(s):  
Cation Exchange ◽  
Bispecific Antibody ◽  
Exchange Chromatography ◽  
Purification Process ◽  
Cation Exchange Chromatography ◽  
Antibody Purification ◽  
Alkaline Cation

Cation exchange chromatography provides effective retrovirus clearance for antibody purification processes

2011 ◽  
Vol 109 (1) ◽  
pp. 157-165 ◽  
Author(s):  
Lisa Connell-Crowley ◽  
Thao Nguyen ◽  
Julia Bach ◽  
Shivanthi Chinniah ◽  
Houman Bashiri ◽  
...  
Keyword(s):  
Cation Exchange ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography ◽  
Antibody Purification

pH–conductivity hybrid gradient cation-exchange chromatography for process-scale monoclonal antibody purification

2007 ◽  
Vol 1175 (1) ◽  
pp. 69-80 ◽  
Author(s):  
Joe X. Zhou ◽  
Shinta Dermawan ◽  
Felix Solamo ◽  
Greg Flynn ◽  
Rosalind Stenson ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Cation Exchange ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography ◽  
Antibody Purification ◽  
Process Scale

Modeling of bispecific antibody elution in mixed-mode cation-exchange chromatography

2017 ◽  
Vol 40 (18) ◽  
pp. 3632-3645 ◽  
Author(s):  
Yi Feng Lee ◽  
Simon Kluters ◽  
Mirjam Hillmann ◽  
Thomas von Hirschheydt ◽  
Christian Frech
Keyword(s):  
Cation Exchange ◽  
Mixed Mode ◽  
Bispecific Antibody ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography

Strong cation-exchange chromatography of proteins on a sulfoalkylated monolithic cryogel

2015 ◽  
Vol 1386 ◽  
pp. 13-21 ◽  
Author(s):  
Işık Perçin ◽  
Rushd Khalaf ◽  
Bastian Brand ◽  
Massimo Morbidelli ◽  
Orhan Gezici
Keyword(s):  
Cation Exchange ◽  
Exchange Chromatography ◽  
Cation Exchange Chromatography ◽  
Strong Cation Exchange ◽  
Strong Cation Exchange Chromatography
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