The Impact of Baseline BMI and HbA1c on Glycemic Control After Treatment with Fast-Acting Insulin Aspart in Individuals with Type 2 Diabetes

2017 ◽  
Vol 41 (5) ◽  
pp. S55
Author(s):  
Victor Milosevski ◽  
Keith Bowering ◽  
Bruce Bode ◽  
Stewart Harris ◽  
Milivoj Piletic ◽  
...  
2021 ◽  
Vol 5 (4) ◽  
Author(s):  
Richard M Bergenstal ◽  
Matthew S D Kerr ◽  
Gregory J Roberts ◽  
Diana Souto ◽  
Yelena Nabutovsky ◽  
...  

Abstract Purpose Suboptimal glycemic control among individuals with diabetes is a leading cause of hospitalizations and emergency department utilization. Use of flash continuous glucose monitoring (flash CGM) improves glycemic control in type 1 and type 2 diabetes, which may result in lower risk for acute and chronic complications that require emergency services and/or hospitalizations. Methods In this retrospective, real-world study, we analyzed IBM MarketScan Commercial Claims and Medicare Supplemental databases to assess the impact of flash CGM on diabetes-related events and hospitalizations in a cohort of 2463 individuals with type 2 diabetes who were on short- or rapid-acting insulin therapy. Outcomes were changes in acute diabetes-related events (ADE) and all-cause inpatient hospitalizations (ACH), occurring during the first 6 months after acquiring the flash CGM system compared with event rates during the 6 months prior to system acquisition. ICD-10 codes were used to identify ADE for hypoglycemia, hypoglycemic coma, hyperglycemia, diabetic ketoacidosis, and hyperosmolarity. Results ADE rates decreased from 0.180 to 0.072 events/patient-year (hazard ratio [HR]: 0.39 [0.30, 0.51]; P < 0.001) and ACH rates decreased from 0.420 to 0.283 events/patient-year (HR: 0.68 [0.59 0.78]; P < 0.001). ADE reduction occurred regardless of age or gender. Conclusions Acquisition of the flash CGM system was associated with reductions in ADE and ACH. These findings provide support for the use of flash CGM in type 2 diabetes patients treated with short- or rapid-acting insulin therapy to improve clinical outcomes and potentially reduce costs.


2019 ◽  
Vol 21 (9) ◽  
pp. 2068-2075 ◽  
Author(s):  
Thomas R. Pieber ◽  
Eva Svehlikova ◽  
Martina Brunner ◽  
Inge B. Halberg ◽  
Karen Margrete Due Thomsen ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1034-P
Author(s):  
EDWARD FRANEK ◽  
MAGNUS EKELUND ◽  
ÓLÖF THÓRISDÓTTIR ◽  
HAK CHUL JANG ◽  
KATARINA LALIC ◽  
...  

2020 ◽  
Vol 132 (4) ◽  
pp. 320-327 ◽  
Author(s):  
Ankita Baru ◽  
Sadaf Amir ◽  
Magnus Ekelund ◽  
Roberta Montagnoli ◽  
João Diogo Da Rocha Fernandes

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