Comparison of anterior ocular biometry between optical low-coherence reflectometry and anterior segment optical coherence tomography in an adult Chinese population

Purpose. To report choroidal thickness and volume in healthy eyes using swept source optical coherence tomography (SS-OCT).Methods. A prospective observational study of 122 patients examined with swept source OCT (DRI-OCT, Topcon, Japan). In each eye, we performed 256 horizontal scans, 12 mm in length and centered on the fovea. We calculated choroidal thickness manually with a built-in caliper and automatically using DRI-OCT mapping software. Choroidal volume was also automatically calculated. We measured axial length with optical low-coherence reflectometry (Lenstar LS 900, Haag-Streit, Switzerland).Results. The choroid has focally increased thickness under the fovea. Choroid was thinnest in the outer nasal quadrant. In stepwise regression analysis, age was estimated as the most significant factor correlating with decreased choroidal thicknessF=23.146, P<0.001followed by axial lengthF=4.902, P=0.03. Refractive error was not statistically significantF=1.16, P=0.28.Conclusions. SS-OCT is the first commercially available system that can automatically create choroidal thickness and volume maps. Choroidal thickness is increased at the fovea and is thinnest nasally. Age and axial length are critical for the estimation of choroidal thickness and volume. Choroidal measurements derived from SS-OCT images have potential value for objectively documenting disease-related choroidal thickness abnormalities and monitoring progressive changes over time.

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Agreement and clinical comparison between a new swept-source optical coherence tomography-based optical biometer and an optical low-coherence reflectometry biometer

Eye ◽

10.1038/eye.2016.241 ◽

2016 ◽

Vol 31 (3) ◽

pp. 437-442 ◽

Cited By ~ 18

Author(s):

P Arriola-Villalobos ◽

J Almendral-Gómez ◽

N Garzón ◽

J Ruiz-Medrano ◽

C Fernández-Pérez ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Optical Coherence ◽

Swept Source ◽

Low Coherence ◽

Clinical Comparison ◽

Optical Biometer ◽

Optical Low Coherence Reflectometry

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Comparison of central corneal thickness using optical low-coherence reflectometry and spectral-domain optical coherence tomography

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2011.11.039 ◽

2012 ◽

Vol 38 (5) ◽

pp. 758-764 ◽

Cited By ~ 7

Author(s):

Alberto López-Miguel ◽

María Encarnación Correa-Pérez ◽

Silvia Miranda-Anta ◽

Darío Iglesias-Cortiñas ◽

María Begoña Coco-Martín ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Central Corneal Thickness ◽

Corneal Thickness ◽

Spectral Domain ◽

Optical Coherence ◽

Low Coherence ◽

Optical Low Coherence Reflectometry

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Effects of 0.01% Atropine Instillation Assessed Using Swept-Source Anterior Segment Optical Coherence Tomography

Journal of Clinical Medicine ◽

10.3390/jcm10194384 ◽

2021 ◽

Vol 10 (19) ◽

pp. 4384

Author(s):

Tadahiro Mitsukawa ◽

Yumi Suzuki ◽

Yosuke Momota ◽

Shun Suzuki ◽

Masakazu Yamada

Keyword(s):

Optical Coherence Tomography ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Eye Drops ◽

Optical Coherence ◽

Short Term ◽

Swept Source ◽

Tomography System ◽

Ocular Biometry ◽

History Of

In this paper, we assessed the short-term effects of 0.01% atropine eye drops on anterior segment parameters by performing ocular biometry using a swept-source anterior segment optical coherence tomography system (AS-OCT). We recruited 17 healthy volunteers (10 men and 7 women aged 24–35 years) with no history of eye disease. Participants without accommodative demand demonstrated significant mydriasis 1 h after the atropine instillation (4.58 ± 0.77 to 5.41 ± 0.83 mm). Pupil diameters with a 5 diopter (D) accommodative stimulus at 1 h (4.70 ± 1.13 mm) and 24 h (4.05 ± 1.06 mm) after atropine instillation were significantly larger than those at baseline (3.71 ± 0.84 mm). Barring pupil diameter, no other biometric parameters significantly changed at any point in time after atropine instillation without accommodative demand. However, with an accommodative stimulus, anterior chamber depth (ACD) at 1 h and posterior curvature of the lens at 1 and 24 h were both significantly larger than those before atropine instillation. Using AS-OCT, we detected a slight decrease in the accommodation response of ocular biometric components evoked by 0.01% atropine instillation. Morphologically, our measurements suggested a change in the ACD and horizontal radius of the lens’ posterior surface curvatures due to the subtle reduction of accommodation.

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