Short-term femtosecond laser cut is not safer than the microkeratome cut

Abstract Purpose: To determine the effect of a single-segment intrastromal corneal ring segment (ICRS;Intacs-SK) on early keratoconus (KCN) or pellucid marginal degeneration (PMD).Methods: It is a prospective interventional study. One-hundred-twenty-four eyes (99 patients) with KCN and 36 eyes (26 patients) with PMD at early stage (the maximum keratometric reading less than 55 diopters) were included to ICRS implantation using femtosecond laser at a tertiary university-based hospital and a private outpatient center. The uncorrected distance and spectacle-corrected visual acuity (UDVA and SCDVA), manifest spherical and cylindrical refractions, and keratometry indices were measured preoperatively and postoperatively, 1 week, 2 and 6 months.Results: One week after surgery, significant improvements were observed in UDVA, SCDVA, cylinder and keratometry readings of both KCN and PMD groups (all P<0.05) with no significant changes afterwards. No significant change occurred in the sphere refraction of PMD group (P=0.10) in contrast to KCN group (P<0.001). Corneal irregularity of KCN group in central 3 and 5 mm zones increased at 1 week (both P<0.001) and then continued to decrease up to 6 months. However, the corneal irregularity of PMD group had significant reduction only at 1 week in 5-mm zone (P=0.02) and 2 months in 3-mm zone (P=0.01) postoperatively. The final efficacy indexes were 1.44±0.71 and 0.87±0.40 in KCN and PMD groups, respectively. Conclusion: Visual acuity and keratometry values reached stability at 1 week, after one-segment Intacs-SK implantation in KCN and PMD groups. The short-term efficacy of the procedure was more in early KCN compared to early PMD.

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Femtosecond Laser-Assisted Cataract Surgery in Glaucoma Patients, Case Series.

10.21203/rs.3.rs-34870/v1 ◽

2020 ◽

Author(s):

Daniela Alvarez-Ascencio ◽

Carolina Fernanda Prado-Larrea ◽

Jesus Jimenez-Roman ◽

Rafael Castañeda-Diez

Keyword(s):

Visual Acuity ◽

Femtosecond Laser ◽

Cataract Surgery ◽

Visual Fields ◽

Case Series ◽

Glaucoma Drainage Device ◽

Angle Closure ◽

Mean Deviation ◽

Short Term ◽

Case Series Study

Abstract BackgroundWe aim to describe the short-term effect of femtosecond laser-assisted cataract surgery (FLACS) in intraocular pressure (IOP), visual acuity (VA), number of hypotensive medications, and visual fields (VF) in glaucomatous eyes.MethodsSingle-center consecutive case series study included patients with a previous glaucoma diagnosis that needed cataract surgery alone or combined with incisional glaucoma procedure. IOP was measured during surgery immediately before and after pretreatment docking with an indentation tonometer. Changes in visual acuity (VA), IOP, number of medications, and VF were evaluated with a 90 day follow up.ResultsTwenty-seven eyes of 27 patients were included. Mean patient age was 70 years, 70% (n = 19) were female. Glaucoma diagnoses were: twelve patients with primary open-angle glaucoma, 13 with angle-closure glaucoma, and 2 with pseudoexfoliation glaucoma. Twenty-one patients underwent cataract surgery alone and 6 combined with an incisional glaucoma procedure (trabeculectomy or glaucoma drainage device implantation). We found no significant differences between pre-docking IOP (17.59 mmHg ± 6.25 SD) and post-docking IOP (17.23 mmHg ± 7.74 SD) p = 0.7. No surgical complications were recorded. The 90-day postoperative follow up revealed no changes from baseline regarding VF mean deviation, mean IOP, and the number of glaucoma medications decreased in both groups.ConclusionFLACS appears to perform well in the short-term in eyes with glaucoma undergoing cataract surgery alone or with an incisional glaucoma procedure. Comparable outcomes to manual phacoemulsification were obtained regarding IOP, VA, and postoperative period evolution.Clinical SignificanceSafety and efficacy of FLACS have not been properly studied in the glaucoma population, we present a case series with different glaucoma diagnoses who underwent FLACS alone or with an incisional glaucoma procedure.

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Optical frequency measurements with a reference cavity stabilized femtosecond laser for improved short term stability

Summaries of Papers Presented at the Lasers and Electro-Optics. CLEO '02. Technical Diges ◽

10.1109/cleo.2002.1034378 ◽

2003 ◽

Author(s):

R.J. Jones ◽

L. Arissian ◽

J.-C. Diels

Keyword(s):

Femtosecond Laser ◽

Optical Frequency ◽

Short Term ◽

Frequency Measurements ◽

Term Stability ◽

Reference Cavity

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Femtosecond laser implantation of a 340-degree intrastromal corneal ring segment in keratoconus: Short-term outcomes

Journal of Cataract & Refractive Surgery ◽

10.1016/j.jcrs.2017.07.026 ◽

2017 ◽

Vol 43 (10) ◽

pp. 1251-1256 ◽

Cited By ~ 4

Author(s):

Mohammad Mehdi Sadoughi ◽

Bahram Einollahi ◽

Amir Reza Veisi ◽

Mohammad Zare ◽

Mohammad Reza Sedaghat ◽

...

Keyword(s):

Femtosecond Laser ◽

Short Term ◽

Intrastromal Corneal Ring ◽

Ring Segment

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Short-term Clinical Outcomes of Femtosecond Laser-assisted Cataract Surgery: Comparison with Conventional Phacoemulsification

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2018.59.5.419 ◽

2018 ◽

Vol 59 (5) ◽

pp. 419

Author(s):

Jae Hwan Choi ◽

Chan Min Yang ◽

Na Yeon Chung ◽

Dong Hui Lim ◽

Tae-Young Chung

Keyword(s):

Femtosecond Laser ◽

Cataract Surgery ◽

Clinical Outcomes ◽

Short Term

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The Effect of NSAID Pretreatment on Aqueous Humor Prostaglandin E2 Concentration in Eyes Undergoing Femtosecond Laser-Assisted Capsulotomy

Journal of Ophthalmology ◽

10.1155/2018/1891249 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Vasilios F. Diakonis ◽

Apostolos G. Anagnostopoulos ◽

Angeliki Moutsiopoulou ◽

Nilufer Yesilirmak ◽

Florence Cabot ◽

...

Keyword(s):

Femtosecond Laser ◽

Anterior Chamber ◽

Aqueous Humor ◽

Prostaglandin E ◽

Short Term ◽

Significant Difference ◽

Group 2 ◽

Side Port ◽

Mean Concentration ◽

Group 1

Purpose. To assess aqueous humor concentration of prostaglandin E2 (PGE2) after capsulotomy creation using a femtosecond laser (FLAC) in patients pretreated with short-term topical ketorolac versus patients without pretreatment. Methods. This prospective study comprised consecutive patients scheduled to undergo cataract surgery using a femtosecond laser platform to perform only capsulotomies. An identical protocol for preoperative mydriasis was used for all the eyes included in the study, while aqueous humor was extracted from the anterior chamber of all patients immediately after the initial side port incision. ELISA was performed to quantify aqueous humor PGE2. The patients were divided into 2 groups; in group 1, the patients received short-term topical ketorolac preoperatively, while the patients in group 2 did not receive NSAID pretreatment. Results. Twenty eyes of 20 patients were included in the study (10 eyes in each group). Mean concentration of aqueous humor PGE2 after FLAC was 392.16 ± 162.00 pg/ml and 622.63 ± 331.84 pg/ml for groups 1 and 2, respectively. A statistically significant difference in aqueous humor PGE2 concentration between the two groups (p<0.05) was demonstrated, with the eyes that received ketorolac pretreatment demonstrating a lower concentration of PGE2. Conclusion. Short-term topical use of ketorolac prior to FLAC seems to prevent excessive release of PGE2 in the anterior chamber of the eyes that received NSAID pretreatment when compared to the eyes that did not receive NSAIDs preoperatively.

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