Metastable zone width and the primary nucleation kinetics for cooling crystallization of NaNO3 from NaCl-NaNO3-H2O system

Using the spectrophotometric method, as a new method, the influence of dextran on the sucrose solubility and metastable zone width has been studied. In agreement with the literature the experimental data show that the dextran has a negligible effect on the sucrose solubility. The results also show that this impurity decreases the sucrose metastable zone width. The study of the nucleation kinetics performed, using Nyvlt’s approach, shows that the dextran accelerates the nucleation and that the nuclei are formed in the solution by instantaneous nucleation. The presence of dextran in the system causes a decrease in the growth rate of sucrose. The growth process of sucrose is governed by a Birth and Spread mechanism. The kinetic parameters of sucrose growth in aqueous solutions without and with dextran were estimated.

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Determination of metastable zone width and nucleation kinetics for combined cooling and antisolvent crystallization of L-asparagine monohydrate in water-isopropanol mixture

Journal of Crystal Growth ◽

10.1016/j.jcrysgro.2018.08.031 ◽

2018 ◽

Vol 501 ◽

pp. 66-73 ◽

Cited By ~ 2

Author(s):

Maheswata Lenka ◽

Debasis Sarkar

Keyword(s):

Nucleation Kinetics ◽

Metastable Zone Width ◽

Zone Width ◽

Antisolvent Crystallization ◽

Metastable Zone ◽

Combined Cooling ◽

Asparagine Monohydrate

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Crystallization of Pentaerythritol I. Solubility, Density and Metastable Zone Width

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19941261 ◽

1994 ◽

Vol 59 (6) ◽

pp. 1261-1269 ◽

Cited By ~ 7

Author(s):

Miloslav Karel ◽

Jaroslav Nývlt ◽

Angelo Chianese

Keyword(s):

Aqueous Solutions ◽

Nucleation Rate ◽

Laboratory Experiments ◽

Metastable Zone Width ◽

Zone Width ◽

Kinetics Of Crystallization ◽

Primary Nucleation ◽

Metastable Zone ◽

Width Measurements ◽

Kinetics Of

Solubility of pentaerythritol in water has been determined using literature data, the polythermal method and the dry residue method. Densities of its aqueous solutions have been measured using a pycnometer. Kinetics of crystallization of the pentaerythritol has been determined in laboratory experiments. In this paper, metastable zone width measurements have been employed for the assessment of the primary nucleation rate.

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The Metastability and Nucleation Thresholds of Ibuprofen in Ethanol and Water-Ethanol Mixtures

International Journal of Chemical Engineering ◽

10.1155/2015/560930 ◽

2015 ◽

Vol 2015 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Abdur Rashid ◽

Edward T. White ◽

Tony Howes ◽

James D. Litster ◽

Ivan Marziano

Keyword(s):

Water Content ◽

Propanoic Acid ◽

Secondary Nucleation ◽

Metastable Zone Width ◽

Zone Width ◽

Primary Nucleation ◽

Metastable Zone ◽

The Times ◽

Induction Times ◽

Supersaturated Solutions

To investigate the crystallization of ibuprofen [((RS)-2-(4-(2-methylpropyl) phenyl) propanoic acid)] from ethanol and water-ethanol mixtures it is necessary to know the nucleation limits of its solutions. In the absence of crystals, nucleation will seldom occur below the PNT (primary nucleation threshold). If crystals are present, nucleation will seldom occur until below the lower SNT (secondary nucleation threshold). Below the SNT, crystals will still grow with negligible nucleation. PNT and SNT values (expressed as relative supersaturationσ) have been measured at 10, 25, and 40°C for ibuprofen in ethanol and in a range of mixtures of different ethanol (E)/water (W) ratios. The induction times were determined from observing the times to nucleate for a range of different supersaturated solutions at a given temperature andE/Wratio. As expected, lowering the supersaturation leads to longer induction times. In ethanol, the SNT values are small and thus the secondary metastable zone width (MSZW) is relatively narrow with a 1 h SNT relative supersaturation typically aboutσ~ 0.05. The 1 h PNT values are much larger with values forσaround 0.3. In aqueous ethanolic mixtures at 25°C, both the PNT and SNT decrease as the water content increases.

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Insight into the role of hydrochloric acid in the thermodynamics and nucleation kinetics behavior of Arbidol hydrochloride monohydrate from Metastable Zone Widths

CrystEngComm ◽

10.1039/d1ce01426a ◽

2021 ◽

Author(s):

Ting Wen ◽

Hairong Wang ◽

Chunrong Li ◽

Jikun Xu ◽

Chuntao Zhang

Keyword(s):

Hydrochloric Acid ◽

Nucleation Kinetics ◽

Nucleation Behavior ◽

Metastable Zone Width ◽

Zone Width ◽

Metastable Zone ◽

Hydrochloride Monohydrate ◽

Insight Into

In order to investigate the nucleation behavior of arbidol hydrochloride monohydrate (AHM) in the aqueous THF (Tetrahydrofuran) solutions, metastable zone width (MSZW) was experimentally determined via the polythermal method, and...

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