Effects of Schisandra chinensis extracts on cough and pulmonary inflammation in a cough hypersensitivity guinea pig model induced by cigarette smoke exposure

2015 ◽  
Vol 165 ◽  
pp. 73-82 ◽  
Author(s):  
Shan Zhong ◽  
Yi-chu Nie ◽  
Zhen-yong Gan ◽  
Xiao-dong Liu ◽  
Zhang-fu Fang ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Pulmonary Inflammation ◽  
Smoke Exposure ◽  
Pig Model ◽  
Cigarette Smoke Exposure ◽  
Schisandra Chinensis ◽  
Guinea Pig Model

Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure

2013 ◽  
Vol 62 (12) ◽  
pp. 1053-1061 ◽  
Author(s):  
Yu-long Luo ◽  
Pei-bo Li ◽  
Chen-chen Zhang ◽  
Yan-fang Zheng ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Chronic Cough ◽  
Neurogenic Inflammation ◽  
Smoke Exposure ◽  
Pig Model ◽  
Cigarette Smoke Exposure ◽  
Guinea Pig Model

Clarithromycin ameliorates pulmonary inflammation induced by short term cigarette smoke exposure in mice

2015 ◽  
Vol 35 ◽  
pp. 60-66 ◽  
Author(s):  
Masuo Nakamura ◽  
Hiroo Wada ◽  
Kojiro Honda ◽  
Keitaro Nakamoto ◽  
Toshiya Inui ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Pulmonary Inflammation ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure ◽  
Short Term

Airway Responsiveness to Intravenous and Inhaled Acetylcholine in the Guinea Pig after Cigarette Smoke Exposure

1987 ◽  
Vol 136 (5) ◽  
pp. 1158-1162 ◽  
Author(s):  
Alan L. James ◽  
Peter Dirks ◽  
Hitoshi Ohtaka ◽  
R. Robert Schellenberg ◽  
James C. Hogg
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Airway Responsiveness ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure

scholarly journals Systemic effects of cigarette smoke exposure in the guinea pig

2006 ◽  
Vol 100 (7) ◽  
pp. 1186-1194 ◽  
Author(s):  
Esther Ardite ◽  
Víctor I. Peinado ◽  
Roberto A. Rabinovich ◽  
José C. Fernández-Checa ◽  
Josep Roca ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure ◽  
Systemic Effects

scholarly journals Pneumocystis murina Infection and Cigarette Smoke Exposure Interact To Cause Increased Organism Burden, Development of Airspace Enlargement, and Pulmonary Inflammation in Mice

2008 ◽  
Vol 76 (8) ◽  
pp. 3481-3490 ◽  
Author(s):  
Paul J. Christensen ◽  
Angela M. Preston ◽  
Tony Ling ◽  
Ming Du ◽  
W. Bradley Fields ◽  
...  
Keyword(s):  
Cigarette Smoke ◽  
Pulmonary Inflammation ◽  
Airflow Obstruction ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure ◽  
Chronic Obstructive ◽  
Respiratory Pathogens ◽  
Obstructive Pulmonary Disease ◽  
Immunocompetent Mice

ABSTRACT Chronic obstructive pulmonary disease (COPD) is characterized by the presence of airflow obstruction and lung destruction with airspace enlargement. In addition to cigarette smoking, respiratory pathogens play a role in pathogenesis, but specific organisms are not always identified. Recent reports demonstrate associations between the detection of Pneumocystis jirovecii DNA in lung specimens or respiratory secretions and the presence of emphysema in COPD patients. Additionally, human immunodeficiency virus-infected individuals who smoke cigarettes develop early emphysema, but a role for P. jirovecii in pathogenesis remains speculative. We developed a new experimental model using immunocompetent mice to test the interaction of cigarette smoke exposure and environmentally acquired Pneumocystis murina infection in vivo. We hypothesized that cigarette smoke and P. murina would interact to cause increases in total lung capacity, airspace enlargement, and pulmonary inflammation. We found that exposure to cigarette smoke significantly increases the lung organism burden of P. murina. Pulmonary infection with P. murina, combined with cigarette smoke exposure, results in changes in pulmonary function and airspace enlargement characteristic of pulmonary emphysema. P. murina and cigarette smoke exposure interact to cause increased lung inflammatory cell accumulation. These findings establish a novel animal model system to explore the role of Pneumocystis species in the pathogenesis of COPD.

Effects of Aclidinium Bromide in a Cigarette Smoke-Exposed Guinea Pig Model of COPD

2013 ◽  
pp. 130913081230007 ◽  
Author(s):  
David Domínguez-Fandos ◽  
Elisabet Ferrer ◽  
Raquel Puig-Pey ◽  
Cristina Carreño ◽  
Neus Prats ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Cigarette Smoke ◽  
Pig Model ◽  
Aclidinium Bromide ◽  
Guinea Pig Model

scholarly journals Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy

2013 ◽  
Vol 14 (1) ◽  
pp. 117 ◽  
Author(s):  
Koen JP Verhees ◽  
Nicholas AM Pansters ◽  
Hoeke A Baarsma ◽  
Alexander HV Remels ◽  
Astrid Haegens ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Guinea Pig ◽  
Muscle Atrophy ◽  
Pulmonary Inflammation ◽  
Pig Model ◽  
Skeletal Muscle Atrophy ◽  
Pharmacological Inhibition ◽  
Guinea Pig Model

scholarly journals Vitamin C Prevents Cigarette Smoke Induced Atherosclerosis in Guinea Pig Model

2010 ◽  
Vol 17 (8) ◽  
pp. 817-827 ◽  
Author(s):  
Tanusree Ray ◽  
Palash Chandra Maity ◽  
Sumana Banerjee ◽  
Suryyani Deb ◽  
Anjan Kumar Dasgupta ◽  
...  
Keyword(s):  
Vitamin C ◽  
Guinea Pig ◽  
Cigarette Smoke ◽  
Pig Model ◽  
Guinea Pig Model

SHORT-TERM CIGARETTE SMOKE EXPOSURE POTENTIATES ENDOTOXIN-INDUCED PULMONARY INFLAMMATION

2007 ◽  
Vol 33 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Girish S. Kulkarni ◽  
Priya P. Nadkarni ◽  
Joseph M. Cerreta ◽  
Shuren Ma ◽  
Jerome O. Cantor
Keyword(s):  
Cigarette Smoke ◽  
Pulmonary Inflammation ◽  
Smoke Exposure ◽  
Cigarette Smoke Exposure ◽  
Short Term
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