scholarly journals Rapid and Cost-Effective Gene Targeting in Rat Embryonic Stem Cells by TALENs

2012 ◽  
Vol 39 (6) ◽  
pp. 275-280 ◽  
Author(s):  
Chang Tong ◽  
Guanyi Huang ◽  
Charles Ashton ◽  
Hongping Wu ◽  
Hexin Yan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Cost Effective

scholarly journals RING1B O-GlcNAcylation regulates gene targeting of polycomb repressive complex 1 in human embryonic stem cells

2015 ◽  
Vol 15 (1) ◽  
pp. 182-189 ◽  
Author(s):  
Julien Jean Pierre Maury ◽  
Chadi A. EL Farran ◽  
Daniel Ng ◽  
Yuin-Han Loh ◽  
Xuezhi Bi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Polycomb Repressive Complex ◽  
Polycomb Repressive Complex 1

scholarly journals Targeting frequency for deletion vectors in embryonic stem cells.

1994 ◽  
Vol 14 (4) ◽  
pp. 2404-2410 ◽  
Author(s):  
H Zhang ◽  
P Hasty ◽  
A Bradley
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Embryonic Stem ◽  
Mouse Embryonic Stem Cells ◽  
Hypoxanthine Phosphoribosyltransferase ◽  
Genomic Deletions ◽  
Wide Range

We analyzed the gene targeting frequencies and recombination products generated by a series of replacement deletion vectors which target the hprt (hypoxanthine phosphoribosyltransferase) locus in mouse embryonic stem cells. We found that the targeting frequency of a 19.2-kb deletion was comparable to that of a 3-kb deletion or a conventional replacement event in which a 1.7-kb fragment was inserted into the locus. We also observed different integration patterns for these deletion vectors. A result of this finding is that a wide range of genomic deletions in embryonic stem cells is feasible.

Germ line transmission and expression of a corrected HPRT gene produced by gene targeting in embryonic stem cells

Cell ◽  
1989 ◽  
Vol 56 (2) ◽  
pp. 313-321 ◽  
Author(s):  
Simon Thompson ◽  
Alan R. Clarke ◽  
Angela M. Pow ◽  
Martin L. Hooper ◽  
David W. Melton
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Germ Line ◽  
Embryonic Stem ◽  
Hprt Gene ◽  
Germ Line Transmission

Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells

1993 ◽  
Vol 2 (4) ◽  
pp. 183-190 ◽  
Author(s):  
James W. McCarrick ◽  
Jane R. Parnes ◽  
Rho H. Seong ◽  
Davor Solter ◽  
Barbara B. Knowles
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Gene Targeting ◽  
Diphtheria Toxin ◽  
Negative Selection ◽  
Embryonic Stem ◽  
Chain Gene ◽  
Diphtheria Toxin A ◽  
Selection Gene ◽  
A Chain
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