scholarly journals 204 A real-world study evaluating adeQUacy of Existing Systemic Treatments for patients with moderate-to-severe Atopic Dermatitis (AD-QUEST): Baseline treatment patterns and unmet needs assessment

2017 ◽  
Vol 137 (5) ◽  
pp. S35
Author(s):  
W. Wei ◽  
E. Ghorayeb ◽  
M.L. Andria ◽  
V. Walker ◽  
J. Chao ◽  
...  
2018 ◽  
Vol 2 ◽  
pp. S30
Author(s):  
Wenhui Wei ◽  
Eric Ghorayeb ◽  
Michael Andria ◽  
Valery Walker ◽  
Jingdong Chao ◽  
...  

Abstract not available. Disclosures: Study sponsored by Regeneron. Copyright 2018 SKIN


2019 ◽  
Vol 123 (4) ◽  
pp. 381-388.e2 ◽  
Author(s):  
Wenhui Wei ◽  
Eric Ghorayeb ◽  
Michael Andria ◽  
Valery Walker ◽  
James Schnitzer ◽  
...  

2020 ◽  
Vol 59 (10) ◽  
Author(s):  
Nicole S. Kim ◽  
Khalad Maliyar ◽  
Luciana Oliveira ◽  
Ashley O’Toole ◽  
Melinda J. Gooderham

2020 ◽  
Vol 83 (6) ◽  
pp. AB144
Author(s):  
Andac Salman ◽  
Meryem Aktas ◽  
Esra Özkürkçü ◽  
Gonca Saraç ◽  
Oktay Taskapan ◽  
...  

2019 ◽  
Vol 15 (25) ◽  
pp. 2943-2953 ◽  
Author(s):  
Kellie J Ryan ◽  
Karen E Skinner ◽  
Ancilla W Fernandes ◽  
Rajeshwari S Punekar ◽  
Melissa Pavilack ◽  
...  

Aim: Little is known about recent treatment patterns among patients with unresected stage III NSCLC in the real world. This retrospective study used medical records from USA community oncology practices to address this knowledge gap. Materials & methods: Eligible patients were stage III NSCLC adults diagnosed between 1 January 2011 and 1 March 2016 without surgical resection. Treatment patterns were assessed across three progression intervals, from stage III diagnosis through third progression. Results: The most common regimen in interval 1 was platinum doublet chemotherapy + radiation therapy, in interval 2 was chemotherapy only, and in interval 3 was non-platinum chemotherapy monotherapy. Conclusion: Most patients were treated following national guidelines, but important unmet needs remain.


2017 ◽  
Vol 22 (1) ◽  
pp. 78-83 ◽  
Author(s):  
Charles W. Lynde ◽  
Marc Bourcier ◽  
Melinda Gooderham ◽  
Lyn Guenther ◽  
Chih-ho Hong ◽  
...  

Background: Atopic dermatitis (AD) is a common and chronic inflammatory skin disease. Approximately 10% of adults with AD do not respond adequately to topical therapies and require phototherapy and/or systemic therapy. Objective: To provide a patient-focused approach to the identification and management of adults with AD who require systemic treatment. Methods: A working group of clinicians experienced in managing AD was convened to review and discuss current evidence on the identification and clinical management of adults with moderate to severe AD. Results: We propose a set of simple and practical clinical criteria for selecting candidates for systemic treatment of AD based on their response to first-line topical therapy and 4 clinical measures that are easily incorporated into routine practice. We also suggest a framework for evaluating systemic treatments according to attributes that are important from both a clinician’s and a patient’s perspective. An algorithm was developed proposing a pathway for treatment of moderate to severe AD in adults. Conclusion: Adults with moderate to severe AD that does not respond adequately to topical therapies currently have few safe and effective treatment options. A clinical algorithm could help guide treatment decisions.


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