Separation of glatiramer acetate and its constituent amino acids using aqueous two-phase systems composed of maltodextrin and acetonitrile

2021 ◽  
Vol 104 ◽  
pp. 544-554
Author(s):  
Bahareh Afzal Shoushtari ◽  
Javad Rahbar Shahrouzi ◽  
Gholamreza Pazuki ◽  
Shahla Shahriari ◽  
Naghmeh Hadidi
Keyword(s):  
Amino Acids ◽  
Glatiramer Acetate ◽  
Two Phase ◽  
Aqueous Two Phase Systems ◽  
Phase Systems

Partitioning behavior of amino acids in aqueous two-phase systems with recyclable volatile salts

2000 ◽  
Vol 743 (1-2) ◽  
pp. 317-325 ◽  
Author(s):  
Mos van Berlo ◽  
Marcel Ottens ◽  
Karel Ch.A.M Luyben ◽  
Luuk A.M van der Wielen
Keyword(s):  
Amino Acids ◽  
Two Phase ◽  
Aqueous Two Phase Systems ◽  
Phase Systems ◽  
Partitioning Behavior

Modeling the partitioning of amino acids in aqueous two phase systems

2014 ◽  
Vol 1329 ◽  
pp. 52-60 ◽  
Author(s):  
Dragana P.C. de Barros ◽  
Sara R.R. Campos ◽  
Pedro P. Madeira ◽  
Ana M. Azevedo ◽  
António M. Baptista ◽  
...  
Keyword(s):  
Amino Acids ◽  
Two Phase ◽  
Aqueous Two Phase Systems ◽  
Phase Systems

scholarly journals Solubility of amino acids, sugars, and proteins

2005 ◽  
Vol 77 (3) ◽  
pp. 559-568 ◽  
Author(s):  
Eugénia Almeida Macedo
Keyword(s):  
Amino Acids ◽  
Mixed Solvents ◽  
Industrial Processes ◽  
Molecular Models ◽  
Two Phase ◽  
Range Interaction ◽  
Liquid Solutions ◽  
Aqueous Two Phase Systems ◽  
Phase Systems ◽  
Very High

The importance of biomolecules is well recognized nowadays, owing to their application in many industrial processes, particularly in the food, pharmaceutical, and cosmetic industries.Amino acids, carbohydrates, and proteins are the three types of biomolecules considered in this review. Solubilities of several amino acids and sugars have been measured in water and, more recently, in mixed solvents, both with or without salts. Experimental data on partition of proteins in aqueous two-phase systems (ATPSs), with polymers or salts, have also been reported in the literature. The experimental techniques used are briefly discussed. Regarding modeling, the complexity of these solutions is very high. Sugars form strong hydrogen bonds with one another and with water or other solvents like alcohols. Liquid solutions with amino acids or proteins present not only short-range interaction forces, but also long-range forces, owing to the appearance of charged species. The capabilities of different molecular models and group-contribution-based methods are shown.

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