Novel cyclopalladated and coordination palladium and platinum complexes derived from α-diphenyl ethanedione bis(thiosemicarbazones): Structural studies and cytotoxic activity against human A2780 and A2780cisR carcinoma cell lines

2007 ◽  
Vol 101 (10) ◽  
pp. 1354-1361 ◽  
Author(s):  
Ana I. Matesanz ◽  
Pilar Souza
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Platinum Complexes ◽  
Structural Studies ◽  
Carcinoma Cell Lines ◽  
Palladium And Platinum Complexes

scholarly journals Cytotoxic activity of gemcitabine, alone or in combination with mitotane, in adrenocortical carcinoma cell lines

2014 ◽  
Vol 382 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Antonina Germano ◽  
Ida Rapa ◽  
Marco Volante ◽  
Nicola Lo Buono ◽  
Sonia Carturan ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Adrenocortical Carcinoma ◽  
Carcinoma Cell ◽  
Carcinoma Cell Lines

Study on Synthesis of (R)-tert-butyl (1-hydroxybut-3-yn-2-yl)carbamate

2014 ◽  
Vol 881-883 ◽  
pp. 438-441
Author(s):  
Lin Jun Tang ◽  
Chang Shan Lv ◽  
Dong Wang Liu ◽  
Shuang Lin Qin ◽  
Li Ping Wang ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Natural Product ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Human Carcinoma ◽  
Tert Butyl ◽  
Carcinoma Cell Lines ◽  
Human Carcinoma Cell ◽  
Jaspine B

(R)-tert-butyl (1-hydroxybut-3-yn-2-yl) carbamate, an key intermediate of the natural product jaspine B which was isolated from various sponges and endowed with cytotoxic activity against several human carcinoma cell lines, was synthesized fromL-Serine in overall yield 41% through seven steps, including esterification, Boc protection, acetonization, reduction,Corey-Fuchs reaction and deprotection.

Study on Synthesis of (R)-Tert-Butyl Benzyl(1-((Tert-Butyldimethylsilyl)Oxy)But-3-Yn-2-Yl)Carbamate

2014 ◽  
Vol 1033-1034 ◽  
pp. 592-595 ◽  
Author(s):  
Lin Jun Tang ◽  
Dong Wang Liu ◽  
Shuang Lin Qin ◽  
Li Ping Wang ◽  
Yu Ping Li ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Natural Product ◽  
Cell Lines ◽  
Carcinoma Cell ◽  
Human Carcinoma ◽  
Tert Butyl ◽  
Carcinoma Cell Lines ◽  
Human Carcinoma Cell ◽  
Jaspine B

(R)-tert-butyl (1-hydroxybut-3-yn-2-yl) carbamate, an intermediate of the natural product jaspine B, which was isolated from various sponges and endowed with cytotoxic activity against several human carcinoma cell lines, was synthesized fromL-Serine in overall yield 30% through seven steps, including esterification, Bn protection, Boc protection, TBS protection, reduction, Corey-Fuchs reaction.

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