Efficient DNA cleavage mediated by mononuclear mixed ligand copper(II) phenolate complexes: The role of co-ligand planarity on DNA binding and cleavage and anticancer activity

2012 ◽  
Vol 114 ◽  
pp. 94-105 ◽  
Author(s):  
Paramasivam Jaividhya ◽  
Rajkumar Dhivya ◽  
Mohamad Abdulkadhar Akbarsha ◽  
Mallayan Palaniandavar
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Dna Binding And Cleavage

Mixed-ligand copper(ii)–sulfonamide complexes: effect of the sulfonamide derivative on DNA binding, DNA cleavage, genotoxicity and anticancer activity

2013 ◽  
Vol 42 (28) ◽  
pp. 10244 ◽  
Author(s):  
Marta González-Álvarez ◽  
Alejandro Pascual-Álvarez ◽  
Lucas del Castillo Agudo ◽  
Alfonso Castiñeiras ◽  
Malva Liu-González ◽  
...  
Keyword(s):  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Sulfonamide Derivative

Mixed-ligand copper(ii) Schiff base complexes: the role of the co-ligand in DNA binding, DNA cleavage, protein binding and cytotoxicity

2016 ◽  
Vol 45 (22) ◽  
pp. 9073-9087 ◽  
Author(s):  
Wen-Jing Lian ◽  
Xin-Tian Wang ◽  
Cheng-Zhi Xie ◽  
He Tian ◽  
Xue-Qing Song ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Protein Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Complexes ◽  
Biological Features

Four novel mixed-ligand copper(ii) Schiff base complexes were synthesized and characterized. The biological features of the complexes and how acetic auxiliary ligands manipulate these features were investigated.

Induction of Cell Death by Ternary Copper(II) Complexes ofl-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity

2009 ◽  
Vol 48 (4) ◽  
pp. 1309-1322 ◽  
Author(s):  
Sethu Ramakrishnan ◽  
Venugopal Rajendiran ◽  
Mallayan Palaniandavar ◽  
Vaiyapuri Subbarayan Periasamy ◽  
Bangalore Suresh Srinag ◽  
...  
Keyword(s):  
Cell Death ◽  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Binding And Cleavage

Mixed ligand copper(ii) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity

2015 ◽  
Vol 44 (22) ◽  
pp. 10210-10227 ◽  
Author(s):  
Rangasamy Loganathan ◽  
Sethu Ramakrishnan ◽  
Mani Ganeshpandian ◽  
Nattamai S. P. Bhuvanesh ◽  
Mallayan Palaniandavar ◽  
...  
Keyword(s):  
Dna Binding ◽  
Protein Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Double Strand Dna

Mixed ligand 5,6-dmp and 3,4,7,8-tmp complexes display more prominent cytotoxicity and higher apoptotic inducing ability.

Mixed-ligand Cu(II)–vanillin Schiff base complexes; effect of coligands on their DNA binding, DNA cleavage, SOD mimetic and anticancer activity

2013 ◽  
Vol 60 ◽  
pp. 216-232 ◽  
Author(s):  
Sartaj Tabassum ◽  
Samira Amir ◽  
Farukh Arjmand ◽  
Claudio Pettinari ◽  
Fabio Marchetti ◽  
...  
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Anticancer Activity ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Complexes

scholarly journals Synthesis of novel calix[4]arene p-benzazole derivatives and investigation of their DNA binding and cleavage activities with molecular docking and experimental studies

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38695-38708
Author(s):  
Seyda Cigdem Ozkan ◽  
Fatma Aksakal ◽  
Aydan Yilmaz
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Experimental Studies ◽  
Binding Properties ◽  
Dna Binding And Cleavage

In this study, p-benzazole-derived calix[4]arene compounds with aromatic structures are synthesized and their DNA cleavage/binding properties are investigated.

Synthesis, Characterization, Antibacterial, DNA Binding and Cleavage Studies of Mixed Ligand Cu(II), Co(II) Complexes

2014 ◽  
Vol 24 (6) ◽  
pp. 1687-1699 ◽  
Author(s):  
B. Ushaiah ◽  
D. Shiva leela ◽  
Mudavath Ravi ◽  
B. Anupama ◽  
Shyam Perugu ◽  
...  
Keyword(s):  
Dna Binding ◽  
Mixed Ligand ◽  
Dna Binding And Cleavage

Mixed ligand ruthenium(II) complexes of 5,6-dimethyl-1,10-phenanthroline: The role of ligand hydrophobicity on DNA binding of the complexes

2006 ◽  
Vol 359 (14) ◽  
pp. 4601-4612 ◽  
Author(s):  
Palanisamy Uma Maheswari ◽  
Venugopal Rajendiran ◽  
Mallayan Palaniandavar ◽  
Reji Thomas ◽  
G.U. Kulkarni
Keyword(s):  
Dna Binding ◽  
Mixed Ligand

Mixed ligand copper(II) complexes of 1,10-phenanthroline with tridentate phenolate/pyridyl/(benz)imidazolyl Schiff base ligands: Covalent vs non-covalent DNA binding, DNA cleavage and cytotoxicity

2014 ◽  
Vol 140 ◽  
pp. 255-268 ◽  
Author(s):  
Chandrasekaran Rajarajeswari ◽  
Mani Ganeshpandian ◽  
Mallayan Palaniandavar ◽  
Anvarbatcha Riyasdeen ◽  
Mohammad Abdulkadher Akbarsha
Keyword(s):  
Schiff Base ◽  
Dna Binding ◽  
Dna Cleavage ◽  
Mixed Ligand ◽  
Schiff Base Ligands
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