Mixed ligand copper(II) complexes of 1,10-phenanthroline with tridentate phenolate/pyridyl/(benz)imidazolyl Schiff base ligands: Covalent vs non-covalent DNA binding, DNA cleavage and cytotoxicity

Four novel mixed-ligand copper(ii) Schiff base complexes were synthesized and characterized. The biological features of the complexes and how acetic auxiliary ligands manipulate these features were investigated.

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Syntheses, crystal structures, DNA binding, DNA cleavage, molecular docking and DFT study of Cu(ii) complexes involving N2O4 donor azo Schiff base ligands

New Journal of Chemistry ◽

10.1039/c7nj03293e ◽

2018 ◽

Vol 42 (1) ◽

pp. 246-259 ◽

Cited By ~ 19

Author(s):

Saikat Banerjee ◽

Pravat Ghorai ◽

Paula Brandão ◽

Dipanjan Ghosh ◽

Sutanwi Bhuiya ◽

...

Keyword(s):

Schiff Base ◽

Molecular Docking ◽

Dna Binding ◽

Crystal Structures ◽

Dna Cleavage ◽

Dft Study ◽

Schiff Base Ligands ◽

Dna Binding And Cleavage

DNA binding and cleavage properties of three novel copper(ii) complexes involving azo Schiff base ligands have been studied.

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Mixed-ligand Cu(II)–vanillin Schiff base complexes; effect of coligands on their DNA binding, DNA cleavage, SOD mimetic and anticancer activity

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2012.08.019 ◽

2013 ◽

Vol 60 ◽

pp. 216-232 ◽

Cited By ~ 83

Author(s):

Sartaj Tabassum ◽

Samira Amir ◽

Farukh Arjmand ◽

Claudio Pettinari ◽

Fabio Marchetti ◽

...

Keyword(s):

Schiff Base ◽

Dna Binding ◽

Anticancer Activity ◽

Dna Cleavage ◽

Mixed Ligand ◽

Schiff Base Complexes

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Oxo-rhenium(V) mixed-ligand complexes with bidentate functionalized phosphines and tridentate Schiff base ligands

Inorganica Chimica Acta ◽

10.1016/s0020-1693(01)00357-7 ◽

2001 ◽

Vol 315 (2) ◽

pp. 205-212 ◽

Cited By ~ 22

Author(s):

Cristina Bolzati ◽

Marina Porchia ◽

Giuliano Bandoli ◽

Alessandra Boschi ◽

Erica Malagò ◽

...

Keyword(s):

Schiff Base ◽

Mixed Ligand ◽

Mixed Ligand Complexes ◽

Schiff Base Ligands ◽

Tridentate Schiff Base

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Synthesis, spectroscopic, thermal analyses, biological activity and molecular docking studies on mixed ligand complexes derived from Schiff base ligands and 2,6‐pyridine dicarboxylic acid

Applied Organometallic Chemistry ◽

10.1002/aoc.4176 ◽

2017 ◽

Vol 32 (3) ◽

pp. e4176 ◽

Cited By ~ 3

Author(s):

Hanan F. Abd El‐Halim ◽

Gehad G. Mohamed

Keyword(s):

Biological Activity ◽

Schiff Base ◽

Molecular Docking ◽

Dicarboxylic Acid ◽

Thermal Analyses ◽

Docking Studies ◽

Mixed Ligand ◽

Mixed Ligand Complexes ◽

Schiff Base Ligands ◽

Pyridine Dicarboxylic Acid

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Copper(ii) complexes based on quinoline-derived Schiff-base ligands: synthesis, characterization, HSA/DNA binding ability, and anticancer activity

MedChemComm ◽

10.1039/c8md00223a ◽

2018 ◽

Vol 9 (10) ◽

pp. 1663-1672 ◽

Cited By ~ 5

Author(s):

Kun Hu ◽

Chensi Liu ◽

Jingui Li ◽

Fupei Liang

Keyword(s):

Schiff Base ◽

Dna Binding ◽

Tumor Cell ◽

Anticancer Activity ◽

Hela Cells ◽

Cell Apoptosis ◽

Schiff Base Ligands ◽

Binding Ability ◽

Tumor Cell Apoptosis ◽

Cell Cycles

Three Cu(ii) complexes (C1–C3) were designed and synthesized.C3, in particular, having a ligand derived from benzocaine, exhibited greater selectivity toward HeLa cells, arrested cell cycles, and promoted tumor cell apoptosis.

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