Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: Role of residues Y93, Y190, K145 and D200

Chemical-Scale Studies on the Role of a Conserved Aspartate in Preorganizing the Agonist Binding Site of the Nicotinic Acetylcholine Receptor†

Biochemistry ◽

10.1021/bi061638b ◽

2007 ◽

Vol 46 (3) ◽

pp. 630-639 ◽

Cited By ~ 35

Author(s):

Amanda L. Cashin ◽

Michael M. Torrice ◽

Kathryn A. McMenimen ◽

Henry A. Lester ◽

Dennis A. Dougherty

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Agonist Binding ◽

The role of tyrosine at the ligand-binding site of the nicotinic acetylcholine receptor

Proceedings of The Royal Society B Biological Sciences ◽

10.1098/rspb.1990.0087 ◽

1990 ◽

Vol 241 (1302) ◽

pp. 207-213 ◽

Cited By ~ 13

Keyword(s):

Ligand Binding ◽

Binding Site ◽

Acetylcholine Receptor ◽

Ligand Binding Site ◽

Structure of the agonist-binding site of the nicotinic acetylcholine receptor. [3H]acetylcholine mustard identifies residues in the cation-binding subsite.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54504-x ◽

1991 ◽

Vol 266 (34) ◽

pp. 23354-23364

Author(s):

J.B. Cohen ◽

S.D. Sharp ◽

W.S. Liu

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Cation Binding ◽

Agonist Binding ◽

Maturation of a postsynaptic domain: Role of small Rho GTPases in organising nicotinic acetylcholine receptor aggregates at the vertebrate neuromuscular junction

Journal of Anatomy ◽

10.1111/joa.13526 ◽

2021 ◽

Author(s):

Angelymar Medina‐Moreno ◽

Juan Pablo Henríquez

Keyword(s):

Neuromuscular Junction ◽

Acetylcholine Receptor ◽

Rho Gtpases ◽

Nicotinic Acetylcholine ◽

Small Rho Gtpases

Expression of the alpha-bungarotoxin binding site of the nicotinic acetylcholine receptor by Escherichia coli transformants.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.84.12.4318 ◽

1987 ◽

Vol 84 (12) ◽

pp. 4318-4321 ◽

Cited By ~ 44

Author(s):

J. M. Gershoni

Keyword(s):

Escherichia Coli ◽

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha Bungarotoxin

Retracted : Role of α7‐nicotinic acetylcholine receptor in human non‐small cell lung cancer proliferation

Cell Proliferation ◽

10.1111/j.1365-2184.2008.00566.x ◽

2008 ◽

Vol 41 (6) ◽

pp. 936-959 ◽

Cited By ~ 57

Author(s):

L. Paleari ◽

A. Catassi ◽

M. Ciarlo ◽

Z. Cavalieri ◽

C. Bruzzo ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Acetylcholine Receptor ◽

Small Cell ◽

Small Cell Lung ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Cancer Proliferation ◽

Probing the Agonist Domain of the Nicotinic Acetylcholine Receptor by Cysteine Scanning Mutagenesis Reveals Residues in Proximity to the α-Bungarotoxin Binding Site†

Biochemistry ◽

10.1021/bi982656z ◽

1999 ◽

Vol 38 (16) ◽

pp. 4912-4921 ◽

Cited By ~ 18

Author(s):

Armin Spura ◽

Tanya S. Russin ◽

Neal D. Freedman ◽

Marianne Grant ◽

James T. McLaughlin ◽

...

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Cysteine Scanning ◽

Cysteine Scanning Mutagenesis

An allosteric binding site of the α7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein

Journal of Biological Chemistry ◽

10.1074/jbc.m117.815316 ◽

2017 ◽

Vol 293 (7) ◽

pp. 2534-2545 ◽

Cited By ~ 15

Author(s):

Florian Delbart ◽

Marijke Brams ◽

Fabian Gruss ◽

Sam Noppen ◽

Steve Peigneur ◽

...

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Binding Protein ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Acetylcholine Binding Protein

A Transmembrane Binding Site at a Subunit Interface for Torpedo Nicotinic Acetylcholine Receptor Potentiators And Inhibitors

Biophysical Journal ◽

10.1016/j.bpj.2009.12.708 ◽

2010 ◽

Vol 98 (3) ◽

pp. 131a

Author(s):

Ayman K. Hamouda ◽

Deidre Stewart ◽

S. Shaukat Husain ◽

Jonathan B. Cohen

Keyword(s):

Binding Site ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Subunit Interface ◽

A Subunit

Role of Nicotinic Acetylcholine Receptor α3 and α7 Subunits in Detrusor Overactivity Induced by Partial Bladder Outlet Obstruction in Rats

International Neurourology Journal ◽

10.5213/inj.2015.19.1.12 ◽

2015 ◽

Vol 19 (1) ◽

pp. 12-18 ◽

Cited By ~ 6

Author(s):

Hyo Sin Kim ◽

Wang Jin Park ◽

Eun Young Park ◽

Jun Sung Koh ◽

Tae-Kon Hwang ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Partial Bladder Outlet Obstruction

Detrusor Overactivity ◽

Bladder Outlet Obstruction ◽

Outlet Obstruction ◽

Nicotinic Acetylcholine ◽