Regional cerebral glucose metabolism in systemic lupus erythematosus patients with major depressive disorder

2017 ◽  
Vol 379 ◽  
pp. 127-130 ◽  
Author(s):  
Tomoyuki Saito ◽  
Maasa Tamura ◽  
Yuhei Chiba ◽  
Omi Katsuse ◽  
Akira Suda ◽  
...  
1990 ◽  
Vol 35 (8) ◽  
pp. 684-688 ◽  
Author(s):  
T.A. Hurwitz ◽  
C. Clark ◽  
E. Murphy ◽  
H. Klonoff ◽  
W.R.W. Martin ◽  
...  

2007 ◽  
Vol 48 (1) ◽  
pp. 14-19 ◽  
Author(s):  
Fabiano G. Nery ◽  
Eduardo F. Borba ◽  
John P. Hatch ◽  
Jair C. Soares ◽  
Eloísa Bonfá ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jin-Feng Wen ◽  
Xin-Wen Guo ◽  
Xiang-Yi Cao ◽  
Ji-Wu Liao ◽  
Ping Ma ◽  
...  

Abstract Background This study aims to compare the difference of the brain changes of glucose metabolism between temporal lobe epilepsy patients (TLE) with major depressive disorder and temporal TLE without major depressive disorder. Methods A total of 24 TLE patients, who met the inclusion criteria of our hospital, were enrolled in this study. They were divided into a TLE with depression group (n = 11) and a TLE without depression group (n = 13), according to the results of the HAMD-24 Scale. Two groups patients were examined using 18F-FDG PET brain imaging. Results The low metabolic regions of the TLE with depression group were mainly found in the left frontal lobe, temporal lobe and fusiform gyrus, while the high metabolic regions of the TLE with depression group were mainly located in the right frontal lobe, visual joint cortex and superior posterior cingulate cortex. Both of the TLE groups had high metabolic compensation in the non-epileptic area during the interictal period. Conclusions There is an uptake difference of 18F-FDG between TLE patients with depression and TLE patients without depression in multiple encephalic regions.


Author(s):  
Francis R. Comerford ◽  
Alan S. Cohen

Mice of the inbred NZB strain develop a spontaneous disease characterized by autoimmune hemolytic anemia, positive lupus erythematosus cell tests and antinuclear antibodies and nephritis. This disease is analogous to human systemic lupus erythematosus. In ultrastructural studies of the glomerular lesion in NZB mice, intraglomerular dense deposits in mesangial, subepithelial and subendothelial locations were described. In common with the findings in many examples of human and experimental nephritis, including many cases of human lupus nephritis, these deposits were amorphous or slightly granular in appearance with no definable substructure.We have recently observed structured deposits in the glomeruli of NZB mice. They were uncommon and were found in older animals with severe glomerular lesions by morphologic criteria. They were seen most commonly as extracellular elements in subendothelial and mesangial regions. The deposits ranged up to 3 microns in greatest dimension and were often adjacent to deposits of lipid-like round particles of 30 to 250 millimicrons in diameter and with amorphous dense deposits.


2000 ◽  
Vol 6 (7) ◽  
pp. 821-825 ◽  
Author(s):  
ELIZABETH LERITZ ◽  
JASON BRANDT ◽  
MELISSA MINOR ◽  
FRANCES REIS-JENSEN ◽  
MICHELLE PETRI

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