Socioeconomic inequalities in knee pain, knee osteoarthritis and health-related quality of life: A population-based cohort study

Abstract Background This study aimed to investigate the effects of weight change and physical activity on the level of knee pain and health-related quality of life in East Asian women with knee osteoarthritis using population-based data. Methods A total of 564 women (mean age, 68.2 years, standard deviation, 8.9 years) aged 50 years or older with knee osteoarthritis (Kellgren-Lawrence grade ≥2) were included in the data analyses from the fifth Korea National Health and Nutrition Examination Survey. Data regarding the radiographic grade, weight change during the past year, physical activity, level of knee pain, and health-related quality of life (EuroQOL five-dimension [EQ-5D] index) were collected. Multiple regression analysis was performed to identify factors significantly affecting the level of knee pain and health-related quality of life in subgroups according to the body mass index (BMI) range (≤22.5, between 22.6 and 27.5, and >27.5 kg/m2). Result In women with 22.5 kg/m227.5 kg/m2, weekly hours of moderate-intensity activity showed significant negative correlation with EQ-5D. Conclusions The effects of weight change and physical activity on knee pain and health-related quality of life could be different according to BMI ranges. Well-designed interventions to improve both knee pain and health-related quality of life need to be investigated in future studies that would assess physical activity, diet, and weight changes.

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Effects of weight change and physical activity on knee pain and health-related quality of life in East Asian women aged 50 years and older with knee osteoarthritis: a population-based study

10.21203/rs.2.11017/v1 ◽

2019 ◽

Author(s):

Young Choi ◽

Chongbum Chang ◽

Seung-Baik Kang ◽

Chin Youb Chung ◽

Moon Seok Park ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Knee Osteoarthritis ◽

Knee Pain ◽

Weight Change ◽

Population Based ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract Objective This study aimed to investigate the effects of weight change and physical activity on the level of knee pain and health-related quality of life in East Asian women with knee osteoarthritis using population-based data. Methods A total of 564 women (mean age, 68.2 years, standard deviation, 8.9 years) aged 50 years or older with knee osteoarthritis (Kellgren-Lawrence grade ≥2) were included in the data analyses from the fifth Korea National Health and Nutrition Examination Survey. Data regarding the radiographic grade, weight change during the past year, physical activity, level of knee pain, and health-related quality of life (EuroQOL five-dimension [EQ-5D] index) were collected. Multiple regression analysis was performed to identify factors significantly affecting the level of knee pain and health-related quality of life in subgroups according to the body mass index (BMI) range (≤22.5, between 22.6 and 27.5, and >27.5 kg/m2). Results In women with 22.5 kg/m227.5 kg/m2, weekly hours of moderate-intensity activity showed significant negative correlation with EQ-5D. Conclusions The effects of weight change and physical activity on knee pain and health-related quality of life could be different according to BMI ranges. Well-designed interventions to improve both knee pain and health-related quality of life need to be investigated in future studies that would assess physical activity, diet, and weight changes.

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Association of Weight Change and Physical Activity with Knee Pain and Health-Related Quality of Life in East Asian Women Aged 50 Years and Older with Knee Osteoarthritis: A Population-Based Study

Kosin Medical Journal ◽

10.7180/kmj.2021.36.2.125 ◽

2021 ◽

Vol 36 (2) ◽

pp. 125-135

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Knee Osteoarthritis ◽

Knee Pain ◽

Weight Change ◽

Population Based ◽

Health Related Quality ◽

Related Quality ◽

Health Related

bjectives: This study aimed to investigate the association of self-reported weight change and physical activity with the level of knee pain and health-related quality of life in East Asian women with knee osteoarthritis using population-based data.Methods: A total of 564 women (mean age, 68.2 years, standard deviation, 8.9 years) aged 50 years or older with knee osteoarthritis (Kellgren-Lawrence (K-L) grade ≥ 2) were included in the data analyses from the fifth Korea National Health and Nutrition Examination Survey. Data regarding the radiographic grade, self-reported weight change during the past year, physical activity, level of knee pain, and health-related quality of life (EuroQOL five- dimension (EQ-5D) index) were collected. Multiple regression analysis was performed to identify factors significantly associated with the level of knee pain and health-related quality of life in subgroups according to the body mass index (BMI) range (≤ 22.5, between 22.6 and 27.5, and > 27.5 kg/m 2 ).Results: In the whole group, the level of knee pain was significantly associated with K-L grade (P < 0.001), and EQ-5D was negatively associated with age (P < 0.001), the level of knee pain (P < 0.001), and weekly hours of vigorous-intensity activity (P = 0.026). In the subgroup analysis, weight gain showed significant association with the level of knee pain only in women with 22.5 kg/m2 < BMI ≤ 27.5 kg/m2 (P = 0.006). Weight gain showed significant association with EQ-5D in women with BMI ≤ 22.5 kg/m2(P = 0.047) whereas weekly hours of moderate-intensity activity was negatively associated with EQ-5D in women with BMI > 27.5 kg/m2 .Conclusions: The association of weight change and physical activity with knee pain and health-related quality of life might be different according to BMI ranges. Well-designed interventions to improve both knee pain and health-related quality of life need to be investigated in future studies that would strictly control physical activity, diet, and weight changes.

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