Botulinum toxin injections for the treatment of hemifacial spasm over 16years

2015 ◽  
Vol 22 (8) ◽  
pp. 1319-1325 ◽  
Author(s):  
Mine Hayriye Sorgun ◽  
Rezzak Yilmaz ◽  
Yusuf Alper Akin ◽  
Fatma Nazli Mercan ◽  
Muhittin Cenk Akbostanci
Author(s):  
Selly Marisdina ◽  
Henry Sugiharto ◽  
A Pradian

Back Ground: Hemifacial spasm is one of movement disorder case that commonly found in daily clinical practice. Epidemiological data are very limited, the average prevalence is 11 per 100,000 population, 14.5 per 100,000 in women and 7.4 per 100,000 in men. In Germany, the estimated prevalence is 8000 to 9000 peoples.1 The incidence of women is more than that of men with a ratio of 2:1. Based on Yaltho and Jankovic study in 2011, out of 215 patients, the ratio of men to women was 1:1.8.2 One study in Indonesia also reported that most of the subjects were female (64.7%).3 Treatment with botulinum toxin injections is preferred to microvascular decompression surgery therapy, but this injection is only effective in a few months and quite expensive. This study is the first study to assess the effectiveness of dry needling on clinical improvement of hemifacial spasm compared to standard therapy of botulinum toxin injection.Methods: The study design was quasi experimental. Total of 24 subjects were divided into two groups. The first group underwent dry needling intervention while the other had botulinum injection. Clinical severity before and after treatment in both groups was assessed using Jankovic and HFS7 scores.Results: In dry needling group there were significant differences between Jankovic and HFS7 score at baseline and at week 1, 2, 3 and 4. While in botox group significant differences were also Jankovic and HFS7 score at baseline and at weeks 2 and 4. There were also a significant difference of Jankovic and HFS7 score when we compared dry needling group to botulinum toxin group.Conclusion: Dry needling can be an alternative treatment for hemifacial spasm, although clinical improvements based on Jankovic and HFS7 scores in dry needling group were not as effective as those with botulinum toxin injections.


Author(s):  
Stephen P. Kraft ◽  
Anthony E. Lang

ABSTRACT:Seventy-six patients with blepharospasm (mean age 56.9 years) received 248 injection treatments with botulinum A exotoxin (mean 3.1 treatments per patient): 87.0% of treatments led to total relief of spasms for a mean interval of 14.1 weeks. The average duration of response remained fairly constant over the first six injection series, although patients with the most severe spasms had shorter intervals than patients with less severe symptoms. Twenty patients with hemifacial spasm (mean age 56.9 years) received 44 treatments (mean 1.9 treatments per patient): In 93.1% of cases there was total relief of periocular and perioral spasms, with a mean interval of 17.4 weeks. The average duration of response for the third series of treatments was much shorter than the mean durations for the first two treatments. Side effects were always transient and included ptosis (23.3%), dry eyes (18.1%), tearing (5.5%), and strabismus (1.4%). No patient had a systemic reaction to the drug. Chronic benign eyelid fasciculations were also successfully treated in 3 patients with single treatments.


2019 ◽  
Vol 34 (9) ◽  
pp. 1401-1403
Author(s):  
Daniel Resende Carvalho Sacramento ◽  
André Lima ◽  
Débora Palma Maia ◽  
Mauro Cunningham ◽  
Ricardo Horta Maciel ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 452-452 ◽  
Author(s):  
Apostolos Apostolidis ◽  
Roshni Popat ◽  
Yiangos Yiangou ◽  
Preston A. Baecker ◽  
Anthony Ford ◽  
...  

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