Does Ketorolac Have a Preemptive Analgesic Effect? A Randomized, Double-Blind, Control Study

2013 ◽  
Vol 71 (12) ◽  
pp. 2029-2034 ◽  
Author(s):  
Rajesh Gutta ◽  
Christopher R. Koehn ◽  
Laura E. James
2014 ◽  
Vol 30 (11) ◽  
pp. 574-578 ◽  
Author(s):  
Hui-Fang Huang ◽  
Pi-Ying Chang ◽  
Yu-Chun Chen ◽  
Kuang-Yi Tseng ◽  
Hung-Te Hsu ◽  
...  

Author(s):  
T.J. Murray

ABSTRACT:We carried out a double blind control study of fatigue in 32 patients with multiple sclerosis, comparing amantadine hydrochloride 100 mg twice a day and placebo. On amantadine 31% had marked improvement; 15.6% moderate improvement; 15.6% mild improvement; and 36.5%unchanged. On placebo, none noted marked improvement; one claimed moderate improvement on either amantadine or placebo. 18.7% reported mild improvement on placebo; and most of them had similar or more response to amantadine. No patient selected placebo over amantadine at the end of the trial. Overall improvement was seen in 62.5% of patients on amantadine and 21.8% on placebo. Additional experience up to two years suggests continued benefit but common and important side-effects.


1991 ◽  
Vol 12 (Supplement) ◽  
pp. 256-258
Author(s):  
Ryoji Kayamori ◽  
Masahiro Mikami ◽  
Katuaki Takino

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