scholarly journals A Retrospective Chart Review of the Antiemetic Effectiveness of Risperidone in Refractory Opioid-Induced Nausea and Vomiting in Advanced Cancer Patients

2007 ◽  
Vol 34 (2) ◽  
pp. 217-222 ◽  
Author(s):  
Yoshiaki Okamoto ◽  
Satoru Tsuneto ◽  
Yoichi Matsuda ◽  
Takaya Inoue ◽  
Hitoshi Tanimukai ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Chart Review ◽  
Retrospective Chart Review ◽  
Nausea And Vomiting ◽  
Advanced Cancer Patients

scholarly journals Incidence and Cause of Delirium in Hospitalized Patients between the Ages of 18 and 56: A Retrospective Chart Review

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Michelle T. Weckmann ◽  
Camden Bay ◽  
Nesrin Abu Ata ◽  
R. Sean Morrison
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Chart Review ◽  
Retrospective Chart Review ◽  
Total Hospital Cost ◽  
Advanced Cancer Patients ◽  
Total Hospital ◽  
Elderly Cancer Patients ◽  
Lung Malignancy ◽  
Distressing Condition

Background. Delirium is a common and devastating condition which has been well characterized in elderly cancer patients, but little is known about delirium in cancer patients under the age of 65. Aim. A pilot study to explore the incidence and potential causes of delirium in hospitalized advanced cancer patients at the age of 18–56 years. Design. A retrospective chart review using validated instruments was used to examine the charts of hematology-oncology admissions in a large academic institution. Data was collected as to the likelihood of delirium and potential precipitants. Results. Delirium incidence was 29% among advanced cancer patients. The associated precipitants of delirium were multifactorial, the most common being medications and infection. Delirium was more common in patients admitted for either acute symptom management or the presence of a lung malignancy. Patients with delirium demonstrated significantly increased total hospital cost and a borderline significant result for increased mortality compared to those without delirium. Conclusions. Delirium is common in hospitalized advanced cancer patients (age 18–56 years) and the cause is typically multifactorial. Delirium results in a more complicated hospital course and likely increased mortality. Further research is needed to define strategies to prevent and treat this common and distressing condition.

Clinical trial participation as part of end-of-life (EOL) cancer care: Associations with medical care near death and bereaved caregivers’ mental health.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 9102-9102
Author(s):  
Andrea Catherine Phelps ◽  
Baohui Zhang ◽  
Holly Gwen Prigerson
Keyword(s):  
Mental Health ◽  
Clinical Trial ◽  
Propensity Score ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Chart Review ◽  
Trial Participation ◽  
Clinical Trial Participation ◽  
Advanced Cancer Patients ◽  
Eol Care

9102 Background: Clinical trial participation is necessary to improve existing therapies, encouraged by national guidelines, and common among advanced cancer patients. The relationships between trial participation and important EOL outcomes such as aggressive care are unknown. Methods: Coping with Cancer Study, an NCI-funded multicenter prospective cohort study of advanced cancer patients and their caregivers, enrolled September 2002 – February 2008. Patients were interviewed at baseline, and clinical trial participation was documented by chart review. Patients were followed to death, (median 4.4 months from baseline). Medical care and quality of life (QOL) in the last week of life was assessed by caregiver interview and chart review. Caregiver interview 6 months post-bereavement assessed QOL and mental health (Structured Clinical Interview for the DSM-IV). The primary outcome was aggressive EOL care (ventilation, resuscitation, or chemotherapy in the last week of life). Secondary outcomes were bereaved caregivers’ mental health and QOL. Propensity-score weighting balanced patient characteristics (e.g. clinical variables, EOL preferences) that differed by trial participation. Propensity-score weighted regression models estimated the effect of trial participation on outcomes. Results: Of 246 patients followed to death with non-missing propensity scores, 27 were clinical trial participants. In propensity-score weighted analyses, trial participation was significantly associated with aggressive EOL care [29.6% v 9.1%; adjusted OR (AOR), 12.14; 95% CI, 3.65-40.36], ICU admission, mechanical ventilation, chemotherapy, and a trend toward inferior QOL near death (p = 0.069). Of 180 matched caregivers, trial participation predicted less mental illness [AOR, 0.15; 95% CI 0.04-0.57], major depression [AOR, 0.25; 95% CI, 0.08-0.80], but was unassociated with QOL (p = 0.15) in adjusted analyses. Conclusions: Clinical trial participation is associated with increased risk of aggressive EOL care for advanced cancer patients, but better mental health for bereaved caregivers.

Olanzapine versus Metoclopramide for Treatment of Nausea and Vomiting in Advanced Cancer Patients with Incomplete Malignant Bowel Obstruction

2020 ◽  
Vol 23 (7) ◽  
pp. 880-881
Author(s):  
Keisuke Kaneishi ◽  
Kengo Imai ◽  
Kazunori Nishimura ◽  
Norio Sakurai ◽  
Hiroyuki Kohara ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Advanced Cancer ◽  
Bowel Obstruction ◽  
Nausea And Vomiting ◽  
Malignant Bowel Obstruction ◽  
Advanced Cancer Patients

The frequency and predictors of end-of-life symptom in patients with advanced cancer.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. e24061-e24061
Author(s):  
Shuji Hiramoto ◽  
Ayako Kikuchi ◽  
Tomohiko Taniyama ◽  
Hori Tetsuo ◽  
Akira Yoshioka ◽  
...  
Keyword(s):  
Cancer Pain ◽  
End Of Life ◽  
Cancer Patients ◽  
Advanced Cancer ◽  
Peritoneal Metastasis ◽  
Group Performance ◽  
Nausea And Vomiting ◽  
Advanced Cancer Patients ◽  
Consciousness Level ◽  
Number Of Patients

e24061 Background: Advanced cancer patients complain of highly distressing symptom at the end-of-life, and important reasons for palliative intervention to relive symptoms. Methods: We analyzed 1282 patients who died of advanced cancer from August 2011 to August 2019 retrospectively. We divided into patients who complain of symptom include fatigue, dyspnea, nausea and vomiting, and cancer pain, or didn’t for 3 days prior to death, and analyzed predictors by multiple logistics method. The primary endpoint of this study was to identify frequency and predictors of end-of-life symptoms in advanced cancer patients. Results: As a background, the median age is 73 years old, 690 males, 592 females, 227 gastroesophageal cancers, 250 biliary pancreatic cancers, 54 hepatocellular carcinomas, 189 colorectal cancer, 251 lung cancers, 71 breast cancers, 58 urological malignancies, 60 gynecological malignancies, 47 head and neck cancer, 31 hematological malignancies, and 22 sarcomas. Number of patients who complained of dyspnea, fatigue, nausea and vomiting, and cancer pain were 235 (18.3%), 318 (24.8%), 81 (6.3%), and 322 (25.1%) at the end-of-life. In a multivariate analysis, peritoneal metastasis (ORs 1.812), with mental (ORs 0.549), palliative referral (ORs 0.680), Eastern Cancer Organization Group Performance Status (ECOG-PS) (OR0.679) and consciousness level (ORs 0.610) was independent predictors in patients with fatigue at the end-of-life. Chest cancer (Odds Ratio 2.635), lung (ORs 2.159), brain (ORs 0.431) and peritoneal metastasis (ORs 0.602), with mental (ORs 0.429), respiratory (ORs 1.960) and metabolic disorder (ORs 0.520), palliative referral (ORs 0.645) and consciousness level (ORs 0.468) was independent predictors in patients with dyspnea. Lung metastasis (ORs 0.480, peritoneal metastasis (ORs 1.812), with anti-cancer therapy (OR 2.244) and consciousness level (ORs 0.610) was independent predictors in patients with nausea and vomiting. Brain metastasis (ORs 0.435, liver metastasis (ORs 1.374), and consciousness level (ORs 0.599) was independent predictors in patients with cancer pain. Conclusions: We reported frequency and independent predictors of end-of-life symptoms in advanced cancer patients. Information on these predictors be useful to explaining about their end-of-life in advance.

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