scholarly journals Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS

2021 ◽  
Author(s):  
Lisa Strasser ◽  
Giorgio Oliviero ◽  
Craig Jakes ◽  
Izabela Zaborowska ◽  
Patrick Floris ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Sample Preparation ◽  
Host Cell ◽  
Drug Products ◽  
Data Independent Acquisition ◽  
Host Cell Proteins ◽  
Automated Sample Preparation ◽  
Antibody Drug

Putative Phospholipase B-Like 2 is Not Responsible for Polysorbate Degradation in Monoclonal Antibody Drug Products

2020 ◽  
Vol 109 (9) ◽  
pp. 2710-2718
Author(s):  
Sisi Zhang ◽  
Hui Xiao ◽  
Michael Goren ◽  
Darya Burakov ◽  
Gang Chen ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Drug Products ◽  
Phospholipase B ◽  
Antibody Drug

Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry

The Analyst ◽  
2013 ◽  
Vol 138 (10) ◽  
pp. 3058 ◽  
Author(s):  
Bo Wang ◽  
Ashley C. Gucinski ◽  
David A. Keire ◽  
Lucinda F. Buhse ◽  
Michael T. Boyne II
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Structural Comparison ◽  
Drug Products ◽  
Anti Cd20 ◽  
Antibody Drug

scholarly journals Comprehensive tracking of host cell proteins during monoclonal antibody purifications using mass spectrometry

mAbs ◽  
2014 ◽  
Vol 6 (3) ◽  
pp. 659-670 ◽  
Author(s):  
Qingchun Zhang ◽  
Andrew M Goetze ◽  
Huanchun Cui ◽  
Jenna Wylie ◽  
Steve Trimble ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Monoclonal Antibody ◽  
Host Cell ◽  
Host Cell Proteins
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