Homodinuclear Ni (II) and Cu (II) Schiff base complexes derived from O-vanillin with a pyrazole bridge: Preparation, crystal structures, DNA and protein (BSA) binding, DNA cleavage, molecular docking and cytotoxicity study

2019 ◽  
Vol 374 ◽  
pp. 145-160 ◽  
Author(s):  
Leila Zarei ◽  
Zahra Asadi ◽  
Michal Dusek ◽  
Vaclav Eigner
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Crystal Structures ◽  
Dna Cleavage ◽  
Schiff Base Complexes ◽  
Bsa Binding

Syntheses, crystal structures, DNA binding, DNA cleavage, molecular docking and DFT study of Cu(ii) complexes involving N2O4 donor azo Schiff base ligands

2018 ◽  
Vol 42 (1) ◽  
pp. 246-259 ◽  
Author(s):  
Saikat Banerjee ◽  
Pravat Ghorai ◽  
Paula Brandão ◽  
Dipanjan Ghosh ◽  
Sutanwi Bhuiya ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dna Binding ◽  
Crystal Structures ◽  
Dna Cleavage ◽  
Dft Study ◽  
Schiff Base Ligands ◽  
Dna Binding And Cleavage

DNA binding and cleavage properties of three novel copper(ii) complexes involving azo Schiff base ligands have been studied.

scholarly journals Utilization and simulation of innovative new binuclear Co(ii), Ni(ii), Cu(ii), and Zn(ii) diimine Schiff base complexes in sterilization and coronavirus resistance (Covid-19)

2021 ◽  
Vol 19 (1) ◽  
pp. 772-784
Author(s):  
Moamen S. Refat ◽  
Ahmed Gaber ◽  
Walaa F. Alsanie ◽  
Mohamed I. Kobeasy ◽  
Rozan Zakaria ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Metal Ions ◽  
Free Ligand ◽  
Schiff Base Complexes ◽  
Hydroxyl Groups ◽  
Binuclear Complexes ◽  
Central Metal ◽  
H Nmr ◽  
Biological Studies

Abstract This article aimed at the synthesis and molecular docking assessment of new diimine Schiff base ligand, namely 2-((E)-(2-((Z)-2-(4-chlorophenyl)-2-hydroxyvinyl)hydrazono) methyl)-6-methoxyphenol (methoxy-diim), via the condensation of 1-(4-chloro-phenyl)-2-hydrazino-ethenol compound with 2-((E)-(2-((Z)-2-(4-chlorophenyl)-2-hydroxy vinyl) hydrazono)methyl)-6-methoxyphenol in acetic acid as well as the preparation of new binuclear complexes of Co(ii), Ni(ii), Cu(ii), and Zn(ii). The following synthesized complexes were prepared in a ratio of 2:1 (metal/ligand). The 1H-NMR, UV-Vis, and FTIR spectroscopic data; molar conductivity measurements; and microanalytical, XRD, TGA/DTG, and biological studies were carried out to determine the molecular structure of these complexes. According to the spectroscopic analysis, the two central metal ions were coordinated with the diamine ligand via the nitrogen of the hydrazine and oxygen of the hydroxyl groups for the first metal ions and via the nitrogen of the hydrazine and oxygen of the phenol group for the second metal ions. Molecular docking for the free ligand was carried out against the breast cancer 3hb5-oxidoreductase and the 4o1v-protein binding kidney cancer and COVID-19 protease, and good results were obtained.

Synthesis, characterization, antimicrobial, BSA binding, DFT calculation, molecular docking and cytotoxicity of Ni(II) complexes with Schiff base ligands

2021 ◽  
Vol 328 ◽  
pp. 115457
Author(s):  
J. Jeevitha Rani ◽  
A. Mary Imelda Jayaseeli ◽  
S. Rajagopal ◽  
S. Seenithurai ◽  
Jeng-Da Chai ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Docking ◽  
Dft Calculation ◽  
Schiff Base Ligands ◽  
Bsa Binding

Syntheses, characterizations, crystal structures, and biological activities of two new mixed ligand Ni(II) and Cu(II) Schiff base complexes

2015 ◽  
Vol 68 (4) ◽  
pp. 632-649 ◽  
Author(s):  
S. Yousef Ebrahimipour ◽  
Maryam Mohamadi ◽  
Jesús Castro ◽  
Nasrin Mollania ◽  
Hadi Amiri Rudbari ◽  
...  
Keyword(s):  
Schiff Base ◽  
Crystal Structures ◽  
Biological Activities ◽  
Mixed Ligand ◽  
Schiff Base Complexes
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