Improvement in functional capacity with spironolactone masks the treatment effect on exercise blood pressure

2021 ◽  
Author(s):  
Myles N. MOORE ◽  
SCHULTZ ◽  
James L. HARE ◽  
Thomas H. MARWICK ◽  
James E. SHARMAN
Keyword(s):  
Blood Pressure ◽  
Functional Capacity ◽  
Treatment Effect ◽  
Exercise Blood Pressure

scholarly journals P88 Improvement in Functional Capacity with Spironolactone Masks the Treatment Effect on Exercise Blood Pressure

2020 ◽  
Vol 25 (Supplement 1) ◽  
pp. S131
Author(s):  
Myles Moore ◽  
Martin Schultz ◽  
James Hare ◽  
Thomas Marwick ◽  
James Sharman
Keyword(s):  
Blood Pressure ◽  
Functional Capacity ◽  
Treatment Effect ◽  
Exercise Blood Pressure

EFFECT OF SUBMAXIMAL EXERCISE ON SYSTOLIC AND DIASTOLIC BLOOD PRESSURE IN YOUNG SEDENTARY NORMOTENSIVE NEPALESE MEDICAL STUDENTS

2003 ◽  
Vol 42 (149) ◽  
pp. 315-6
Author(s):  
Arijit Ghosh ◽  
T Pramanik
Keyword(s):  
Blood Pressure ◽  
Medical Students ◽  
Diastolic Blood Pressure ◽  
Submaximal Exercise ◽  
Muscular Exercise ◽  
Normal Blood ◽  
Normal Blood Pressure ◽  
Standing Posture ◽  
Normal Range ◽  
Exercise Blood Pressure

Higher exercise blood pressure represents low cardiorespiratory status of an individual and vice versa. Thechanges in systolic and diastolic blood pressure in response to rhythmic isotonic muscular exercise in sedentaryyoung normotensive Nepalese students were assessed. Normal blood pressure in standing posture in maleand female subjects are about 115 / 75 mm of Hg. and 106 / 71 mm of Hg. respectively. Just after the exercisesystolic blood pressure increases moderately in both the sexes, whereas diastolic blood pressure remainsunchanged in most of the females. Diastolic blood pressure is found to be decreased slightly in the males,just after exercise. The present study indicates the cardiorespiratory status of the Napalese medical studentsis within normal range.

Feasibility of hybrid telerehabilitation as component of a novel comprehensive care program after acute myocardial infarction in a one-year follow-up preliminary experience of a single center

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
E Piotrowicz ◽  
P Orzechowski ◽  
I Kowalik ◽  
R Piotrowicz
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Acute Myocardial Infarction ◽  
Heart Rate ◽  
Functional Capacity ◽  
Care Program ◽  
Comprehensive Care ◽  
Monitoring Center ◽  
One Year

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): National Health Fund Background. A novel comprehensive care program after acute myocardial infarction (AMI) „KOS-zawał" was implemented in Poland. It includes acute intervention, complex revascularization, implantation of cardiovascular electronic devices (in case of indications), rehabilitation or hybrid telerehabilitation (HTR) and scheduled outpatient follow-up. HTR is a unique component of this program. The purpose of the pilot study was to evaluate a feasibility, safety and patients’ acceptance of HTR as component of a novel care program after AMI and to assess mortality in a one-year follow-up. Methods The study included 55 patients (LVEF 55.6 ± 6.8%; aged 57.5 ± 10.5 years). Patients underwent a 5-week HTR based on Nordic walking, consisting of an initial stage (1 week) conducted within an outpatient center and a basic stage (4-week) home-based telerehabilitation five times weekly. HTR was telemonitored with a device adjusted to register electrocardiogram (ECG) recording and to transmit data via mobile phone network to the monitoring center. The moments of automatic ECG registration were pre-set and coordinated with exercise training. The influence on physical capacity was assessed by comparing changes in functional capacity (METs) from the beginning and the end of HTR. Patients filled in a questionnaire in order to assess their acceptance of HTR at the end of telerehabilitation. Results HTR resulted in a significant improvement in functional capacity and workload duration in exercise test (Table). Safety: there were neither deaths nor adverse events during HTR. Patients accepted HTR, including the need for interactive everyday collaboration with the monitoring center. Prognosis all patients survived in a one-year follow-up. Conclusions Hybrid telerehabilitation is a feasible, safe form of rehabilitation, well accepted by patients. There were no deaths in a one-year follow-up. Outcomes before and after HTR Before telerehabilitation After telerehabilitation P Exercise time [s] 381.5 ± 92.0 513.7 ± 120.2 <0.001 Maximal workload [MET] 7.9 ± 1.8 10.1 ± 2.3 <0.001 Heart rate rest [bpm] 68.6 ± 12.0 66.6 ± 10.9 0.123 Heart rate max effort [bpm] 119.7 ± 15.9 131.0 ± 20.1 <0.001 SBP rest [mmHg] 115.6 ± 14.8 117.7 ± 13.8 0.295 DBP rest [mmHg] 74.3 ± 9.2 76.2 ± 7.3 0.079 SBP max effort [mm Hg] 159.5 ± 25.7 170.7 ± 25.5 0.003 DBP max effort [mm Hg] 84.5 ± 9.2 87.2 ± 9.3 0.043 SBP systolic blood pressure, DBP diastolic blood pressure.

Sex-Based Differences in Peak Exercise Blood Pressure Indexed to Oxygen Consumption Among Competitive Athletes

2021 ◽  
Author(s):  
Bradley J. Petek ◽  
Sarah K. Gustus ◽  
Timothy W. Churchill ◽  
J. Sawalla Guseh ◽  
Garrett Loomer ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Oxygen Consumption ◽  
Peak Exercise ◽  
Exercise Blood Pressure ◽  
Competitive Athletes

scholarly journals Sex and exercise-mode differences in post-exercise blood pressure and heart rate variability responses during a workday

2019 ◽  
Vol 25 (1) ◽  
Author(s):  
Igor Moraes Mariano ◽  
Daniela Coelho Domingos ◽  
Ana Luiza Amaral Ribeiro ◽  
Tiago Peçanha ◽  
Herbert Gustavo Simões ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Post Exercise ◽  
Exercise Mode ◽  
Exercise Blood Pressure

43 POST-EXERCISE BLOOD PRESSURE AND HEMODYNAMIC RESPONSES IN YOUNG BLACK MALES

1993 ◽  
Vol 25 (Supplement) ◽  
pp. S8
Author(s):  
S. A. Headley ◽  
J. M. Claiborne ◽  
C. R. Lottes ◽  
C. G. Korba
Keyword(s):  
Blood Pressure ◽  
Black Males ◽  
Hemodynamic Responses ◽  
Post Exercise ◽  
Exercise Blood Pressure ◽  
Young Black Males

Abstract WP396: Analysis of Patients With Excessively High Pre-Randomization Systolic Blood Pressure and Effect of Intensive Systolic Blood Pressure Reduction in Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) 2

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Adnan I Qureshi ◽  
Lydia D Foster ◽  
Iryna Lobanova ◽  
Wei Huang ◽  
Jose I Suarez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Treatment Effect ◽  
Standard Treatment ◽  
Blood Pressure Reduction ◽  
Intensive Treatment ◽  
Hematoma Expansion ◽  
Disability Score ◽  
Modifying Effect ◽  
Current Guidelines

Background: Current guidelines recommend for intracerebral hemorrhage (ICH) patients with the systolic blood pressure (SBP) >220 mmHg, unlike those with initial SBP 150-220 mm, Hg, the efficacy of aggressive reduction of SBP is less well established and further studies are recommended. Methods: We analyzed data from ATACH 2 trial which randomized patients with initial SBP >180 mm Hg to intensive (goal 110-139 mmHg) and standard (goal 140-179 mmHg) SBP reduction using IV nicardipine within 4.5 hours of symptom onset. We compared the characteristics and outcomes between patients with pre- randomization SBP ≥220 mm Hg and those with initial SBP <220 mm Hg. We analyzed the modifying effect (interaction test) of pre-randomization SBP ≥220 mm Hg on treatment effect (intensive versus standard) on death or disability (score 4-6 on modified Rankin scale) at 3-months post-randomization ascertained by a blinded investigator. Results: Of 1000 randomized subjects, 48 subjects had a pre-randomization SBP ≥ 220 mm Hg (mean age 57.8 years, 65% men); 24 were assigned to intensive-treatment and standard-treatment each. The rate of death or disability at 3 months (47.9% versus 37.7%, odds ratio (OR): 1.52, 95% confidence interval (CI): 0.43 to 1.5, 0.85 to 2.72) and hematoma expansion within 24 hours (30.0% versus 21.2%, OR: 1.60; 95% CI: 0.80 to 3.20) was not different among subjects with SBP≥220 mm Hg SBP and those with SBP < 220 mm Hg. Rates of hematoma expansion (19% and 27.3%, OR: 0.63; 95% CI: 0.15 to 2.6) and neurological deterioration (8.7% versus 17.4%, OR: 0.45; 95% CI: 0.07 to 2.8) within 24 hours were not different between those randomized to intensive treatment and those to standard treatment in patients with SBP≥220 mm Hg. The interaction between initial SBP ≥220 mm Hg and treatment effect on death or disability was significant (p=0.0111). Conclusions: Patients with pre-randomization SBP ≥220 mm Hg did not have higher rates of hematoma expansion or death or disability compared to those with SBP <220 mm Hg. The interaction of pre- randomization SBP ≥220 mm Hg with the treatment effect and a non-significantly higher rate of death or disability associated with intensive treatment requires further studies.

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