scholarly journals Mean-field modeling of the basal ganglia-thalamocortical system. II

2009 ◽  
Vol 257 (4) ◽  
pp. 664-688 ◽  
Author(s):  
S.J. van Albada ◽  
R.T. Gray ◽  
P.M. Drysdale ◽  
P.A. Robinson
2012 ◽  
Vol 12 (02) ◽  
pp. 1240004 ◽  
Author(s):  
ALIREZA NAHVI ◽  
FARIBA BAHRAMI ◽  
SAMIRA HEMMATI

In this paper, we investigated effects of deep brain stimulation (DBS) on Parkinson's disease (PD) when different target sites in the basal ganglia are stimulated. The targets which are investigated are subthalamic nucleus (STN), globus pallidus interna (GPi), and globus pallidus externa (GPe). For this purpose we used a computational model of the basal ganglia-thalamocortical system (BGTCS) with parameters calculated for mean field. This model is able to reproduce both the normal and Parkinsonian activities of basal ganglia, thalamus and cortex in a unified structure. In the present study, we used a mean-field model of the BGTCS, allowing a more complete framework to simulate DBS and to interpret its effects in the BGTCS. Our results suggest that DBS in the STN and GPe could restore the thalamus relay activity, while DBS in the GPi could inhibit it. Our results are compatible with the experimental and the clinical outcomes about the effects of DBS of different targets.


2021 ◽  
Vol 153 ◽  
pp. 103685
Author(s):  
G. Girard ◽  
K. Frydrych ◽  
K. Kowalczyk-Gajewska ◽  
M. Martiny ◽  
S. Mercier

2018 ◽  
Vol 146 ◽  
pp. 194-207 ◽  
Author(s):  
Ludovic Maire ◽  
Julien Fausty ◽  
Marc Bernacki ◽  
Nathalie Bozzolo ◽  
Pascal De Micheli ◽  
...  

2000 ◽  
Vol 33 (22) ◽  
pp. 8488-8496 ◽  
Author(s):  
Nadezhda P. Shusharina ◽  
Per Linse ◽  
Alexei R. Khokhlov

2013 ◽  
Vol 260 ◽  
pp. 145-158 ◽  
Author(s):  
Martin Burger ◽  
Jan Haškovec ◽  
Marie-Therese Wolfram
Keyword(s):  

2000 ◽  
Vol 84 (14) ◽  
pp. 3129-3132 ◽  
Author(s):  
J. Elezgaray ◽  
C. Léger ◽  
F. Argoul
Keyword(s):  

2009 ◽  
Vol 60 (3) ◽  
pp. 479-497 ◽  
Author(s):  
Patrizio Neff ◽  
Jena Jeong ◽  
Ingo Münch ◽  
Hamid Ramezani

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