scholarly journals Caregiver Burden in Fragile X Syndrome as a Function of a Health State Utility Index in the United States

2013 ◽  
Vol 16 (7) ◽  
pp. A625
Author(s):  
M. Raspa ◽  
E. Bishop ◽  
S.D. Candrilli ◽  
D. Mitra ◽  
P. Sacco ◽  
...  
Keyword(s):  
United States ◽  
Fragile X Syndrome ◽  
Caregiver Burden ◽  
Fragile X ◽  
The United States ◽  
Health State Utility ◽  
Health State ◽  
Utility Index

scholarly journals Health Care Resource Use and Direct Costs Associated with Fragile X Syndrome (FXS) in the United States

2013 ◽  
Vol 16 (7) ◽  
pp. A621
Author(s):  
F. Vekeman ◽  
M. Gauthier-Loiselle ◽  
E. Faust ◽  
P. Lefebvre ◽  
R. Lahoz ◽  
...  
Keyword(s):  
United States ◽  
Health Care ◽  
Fragile X Syndrome ◽  
Resource Use ◽  
Fragile X ◽  
The United States ◽  
Direct Costs ◽  
Health Care Resource ◽  
Health Care Resource Use

Patient and Caregiver Burden Associated With Fragile X Syndrome in the United States

2015 ◽  
Vol 120 (5) ◽  
pp. 444-459 ◽  
Author(s):  
Francis Vekeman ◽  
Marjolaine Gauthier-Loiselle ◽  
Elizabeth Faust ◽  
Patrick Lefebvre ◽  
Raquel Lahoz ◽  
...  
Keyword(s):  
Fragile X Syndrome ◽  
Caregiver Burden ◽  
Propensity Scores ◽  
Claims Data ◽  
Fragile X ◽  
Indirect Costs ◽  
The United States ◽  
Direct Costs ◽  
High Dimensional ◽  
Disability Leave

Abstract This study evaluated the incremental healthcare costs associated with Fragile X syndrome (FXS) for patients and their caregivers. Using administrative healthcare claims data (1999-2012), subjects with ≥ 1 FXS diagnosis (ICD-9-CM: 759.83) were matched 1:5 with non-FXS controls using high-dimensional propensity scores. Costs and resource utilization were examined. Among employees, payment for disability leave and absenteeism were also examined. We identified 590 FXS and 2,950 non-FXS individuals along with 647 and 2,611 caregivers, respectively. FXS patients and their caregivers experienced higher all-cause direct costs compared to control cohorts (total[SD]: $14,677[46,752] vs. $6,103[26,081]; $5,259[19,360] vs. $2,120[6,425], respectively, p < 0.05). Employed FXS patients and caregivers had higher indirect costs compared to their controls (total[SD]: $4,477[5,161] vs. $1,751[2,556]; $2,641[4,238] vs. $1,211[1,936], respectively, p < 0.05).

scholarly journals Finally... Real Utility Scores for Hepatitis C Patients!

2004 ◽  
Vol 18 (6) ◽  
pp. 411-412
Author(s):  
Kevork M Peltekian
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
The United States ◽  
Hcv Infection ◽  
Health State Utility ◽  
Decompensated Cirrhosis ◽  
Health State ◽  
Compensated Cirrhosis ◽  
Progression Of Disease ◽  
Utility Scores

Chong and colleagues (1) used gold-standard methods to assess health-state utilities in 193 outpatients at various stages of liver disease due to chronic hepatitis C (HCV) infection. They showed worsening of health-state utility scores with progression of disease from mild to moderate chronic hepatitis, to compensated cirrhosis, to decompensated cirrhosis and to hepatocellular carcinoma. They also confirmed improvement in health-state utility scores after liver transplantation and with sustained virological response (SVR) to treatment of HCV infection. Patients with HCV infection had lower health-state utility scores than the general Canadian population (PÃ0.001) and significantly poorer quality of life compared with population norms in the United States (PÃ0.005).

scholarly journals Caregiving centenarians: Cross-national comparison in Caregiver-Burden between the United States and Japan

2018 ◽  
Vol 24 (5) ◽  
pp. 774-783 ◽  
Author(s):  
J. Cho ◽  
T. Nakagawa ◽  
P. Martin ◽  
Y. Gondo ◽  
L. W. Poon ◽  
...  
Keyword(s):  
United States ◽  
Caregiver Burden ◽  
The United States ◽  
National Comparison ◽  
Cross National

An assessment of the human health impact of seven leading foodborne pathogens in the United States using disability adjusted life years

2015 ◽  
Vol 143 (13) ◽  
pp. 2795-2804 ◽  
Author(s):  
E. SCALLAN ◽  
R. M. HOEKSTRA ◽  
B. E. MAHON ◽  
T. F. JONES ◽  
P. M. GRIFFIN
Keyword(s):  
United States ◽  
Foodborne Pathogens ◽  
Health Impact ◽  
The United States ◽  
Health State ◽  
Foodborne Disease ◽  
Health States ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Safety Interventions

SUMMARYWe explored the overall impact of foodborne disease caused by seven leading foodborne pathogens in the United States using the disability adjusted life year (DALY). We defined health states for each pathogen (acute illness and sequelae) and estimated the average annual incidence of each health state using data from public health surveillance and previously published estimates from studies in the United States, Canada and Europe. These pathogens caused about 112 000 DALYs annually due to foodborne illnesses acquired in the United States. Non-typhoidal Salmonella (32 900) and Toxoplasma (32 700) caused the most DALYs, followed by Campylobacter (22 500), norovirus (9900), Listeria monocytogenes (8800), Clostridium perfringens (4000), and Escherichia coli O157 (1200). These estimates can be used to prioritize food safety interventions. Future estimates of the burden of foodborne disease in DALYs would be improved by addressing important data gaps and by the development and validation of US-specific disability weights for foodborne diseases.

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