A circulating non-coding RNA panel as an early detection predictor of non-small cell lung cancer

Life Sciences ◽  
2016 ◽  
Vol 151 ◽  
pp. 235-242 ◽  
Author(s):  
Hua Peng ◽  
Jia Wang ◽  
Jia Li ◽  
Mei Zhao ◽  
Sheng-kai Huang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna

scholarly journals Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer

2011 ◽  
Vol 30 (6) ◽  
pp. 407-414 ◽  
Author(s):  
Juan Wei ◽  
Wen Gao ◽  
Cheng-Jun Zhu ◽  
Yi-Qian Liu ◽  
Zhu Mei ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Plasma Microrna

scholarly journals 30PD Novel plasma circulating microRNA signature for early detection of non-small cell lung cancer in liquid biopsy

2016 ◽  
Vol 11 (4) ◽  
pp. S68
Author(s):  
T. Powrózek ◽  
P. Krawczyk ◽  
D. Kowalski ◽  
B. Kuźnar-Kamińska ◽  
K. Winiarczyk ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Liquid Biopsy ◽  
Small Cell ◽  
Circulating Microrna ◽  
Small Cell Lung

Long non-coding RNA DARS-AS1 promotes tumorigenesis of non-small cell lung cancer via targeting miR-532-3p

2021 ◽  
Vol 112 (3) ◽  
Author(s):  
Dongguo LIU ◽  
Haibo LIU ◽  
Zongpeng JIANG ◽  
Minglian CHEN ◽  
Shuncui GAO
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna ◽  
Long Non Coding Rna

Profiling Tumor-Associated Antibodies for Early Detection of Non-small Cell Lung Cancer

2006 ◽  
Vol 1 (6) ◽  
pp. 513-519 ◽  
Author(s):  
Li Zhong ◽  
Sarah P. Coe ◽  
Arnold J. Stromberg ◽  
Nada H. Khattar ◽  
James R. Jett ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Early Detection ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals Long non-coding RNA AK001796 contributes to cisplatin resistance of non-small cell lung cancer

2017 ◽  
Vol 16 (4) ◽  
pp. 4107-4112 ◽  
Author(s):  
Bin Liu ◽  
Chun-Feng Pan ◽  
Teng Ma ◽  
Jun Wang ◽  
Guo-Liang Yao ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Cisplatin Resistance ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna ◽  
Long Non Coding Rna

scholarly journals Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway

2021 ◽  
Vol 11 ◽  
Author(s):  
Ye Sun ◽  
Wenjun Liu ◽  
Qiuyu Zhao ◽  
Ruiqi Zhang ◽  
Jianbo Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Death ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Resistant Cell ◽  
Resistant Cell Line ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna ◽  
Rate Limiting

miRNA-21 is a single-stranded non-coding RNA that is highly expressed in a variety of tumor cells. It participates in tumor cell proliferation, metabolism, metastasis, and drug resistance. Here, we tested the potential mechanism of miRNA-21 in cisplatin-resistant non-small cell lung cancer A549/DDP (human lung adenocarcinoma drug-resistant cell line) cells. A549 and A549/DDP RNAs were sequenced to show that miRNA-21 was highly expressed in the latter, and this was verified by qRT-PCR. In addition, we found that miRNA-21 combined with cisplatin can significantly inhibit glycolysis and glycolysis rate-limiting enzyme protein expression in A549/DDP cells. We also found that miRNA-21 combined with cisplatin can promote A549/DDP cell death. Further investigations showed that miRNA-21 combined with cisplatin caused excessive inactivation of the pI3K/AKT/mTOR/HIF-1α signaling pathway in cisplatin-resistant A549/DDP cells. Hence, reduction of the expression of miRNA-21 in combination with cisplatin chemotherapy may effectively improve the therapeutic effect on patients with non-small cell lung cancer, and this may provide a theoretical basis for the treatment of this disease.

scholarly journals The long non-coding RNA LSINCT5 promotes malignancy in non-small cell lung cancer by stabilizing HMGA2

Cell Cycle ◽  
2018 ◽  
Vol 17 (10) ◽  
pp. 1188-1198 ◽  
Author(s):  
Yuheng Tian ◽  
Nali Zhang ◽  
Shuwen Chen ◽  
Yuan Ma ◽  
Yanyan Liu
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna ◽  
Long Non Coding Rna

Long non-coding RNA AFAP1-AS1 plays an oncogenic role in promoting cell migration in non-small cell lung cancer

2018 ◽  
Vol 75 (24) ◽  
pp. 4667-4681 ◽  
Author(s):  
Juan He ◽  
Ke Wu ◽  
Chenglin Guo ◽  
Jian-Kang Zhou ◽  
Wenchen Pu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Migration ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Small Cell Lung ◽  
Non Coding Rna ◽  
Long Non Coding Rna
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