Lung parenchymal invasion in pulmonary carcinoid tumor: An important histologic feature suggesting the diagnosis of atypical carcinoid and poor prognosis

Lung Cancer ◽  
2013 ◽  
Vol 80 (2) ◽  
pp. 146-152 ◽  
Author(s):  
Sang Yun Ha ◽  
Jae Jun Lee ◽  
Junhun Cho ◽  
Jiyeon Hyeon ◽  
Joungho Han ◽  
...  
2020 ◽  
Vol 9 (4) ◽  
Author(s):  
Dathe Z Benissan-Messan ◽  
Robert E Merritt ◽  
Konstantin Shilo ◽  
Desmond M D'Souza ◽  
Peter J Kneuertz

Ectopic adrenocorticotropic hormone ( ACTH) syndrome is rare and identification of its source is often challenging. We report the case of an ectopic Cushing syndrome in a young adult male secondary to an occult ACTH producing atypical carcinoid tumor. Extensive biochemical and imaging workup was unrevealing. The diagnosis was aided by Ga-DOTA PET scan demonstrating a suspicious left upper lobe lung nodule. The patient underwent video-assisted thoracoscopic exploration with wedge resection and mediastinal lymphadenectomy of a T2aN2M0 atypical carcinoid, resulting in the normalization of ACTH levels and complete resolution of symptoms. The role of a Ga-DOTA PET scan in diagnosing pulmonary carcinoid tumors and their management are discussed.


2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Hikaru Watanabe ◽  
Kohei Abe ◽  
Naoki Kanauchi

Abstract Background It is uncommon for a bronchial stump-related complication to develop during the remote postoperative period in a case of obstructive pneumonia owing to migration of the suture material. Here, we describe a case of bronchial obstructive pneumonia that developed owing to migration of the suture material in the airway 8 years after pulmonary resection. Case presentation A 34-year-old woman underwent left lower lobectomy for a pulmonary carcinoid tumor (pT1bN0M0-stage IA) in 2010. She experienced obstructive pneumonia, and chest computed tomography revealed a mass protruding from the bronchial stump to the bronchial lumen in 2018. After treatment for pneumonia, flexible bronchoscopy showed the presence of a fibrous suture material (Teflon pledget) completely obstructing the left second carina. A week later, the Teflon pledget obstructing the bronchial lumen was removed using a flexible bronchoscope with the patient under general anesthesia. The procedure was completed without removing the small amount of granulation tissue because the bronchial lumen opened after removing the Teflon pledget. She has remained asymptomatic for 1 year after removal. Conclusions In this case, the complication of obstructive pneumonia developed owing to migration of the non-absorbable suture materials used to suture the bronchial stump. Bronchoscopic management of this rare complication comprised endobronchial removal with the patient under general anesthesia. Given our experience with this case, we believe that such conservative management should allow for excellent results in most instances and avoid the need for reoperation.


2015 ◽  
Vol 62 (4) ◽  
pp. 202-204
Author(s):  
Irene Acevedo-Báñez ◽  
Juan Luis Tirado-Hospital ◽  
Ovidio Muñiz-Grijalvo ◽  
Miguel Angel Mangas-Cruz ◽  
Francisco Javier García-Gómez

2001 ◽  
Vol 14 (9) ◽  
pp. 880-885 ◽  
Author(s):  
Yulin Liu ◽  
Charles D. Sturgis ◽  
Dana M. Grzybicki ◽  
Katherine M. Jasnosz ◽  
Peter R. Olson ◽  
...  

2018 ◽  
Vol 57 (8) ◽  
pp. 1109-1116 ◽  
Author(s):  
Tiina Vesterinen ◽  
Sanna Mononen ◽  
Kaisa Salmenkivi ◽  
Harri Mustonen ◽  
Jari Räsänen ◽  
...  

1996 ◽  
Vol 43 (4) ◽  
pp. 623 ◽  
Author(s):  
Dong Soo Lee ◽  
Tae Won Lee ◽  
Gye Yeon Kim ◽  
Hwi Jung Kim ◽  
So Hyang Song ◽  
...  

2015 ◽  
Vol 01 (01) ◽  
pp. 055-057
Author(s):  
Anant Dinesh ◽  
Himanshu Shukla ◽  
Reetesh Ranjan ◽  
Surender Dabas

AbstractAtypical carcinoid tumor of the larynx is a particularly rare occurrence. Here, we report a patient with a laryngeal neuroendocrine tumor (NET) who was treated with transoral robotic surgery-supraglottic laryngectomy (TORS-SL). A 73-year-old male patient, a known smoker, presented with throat pain and hoarseness for 1 month. Endoscopic laryngeal examination and magnetic resonance imaging revealed a left supraglottic mass. The results of histopathologic examination and immunohistochemical analysis were consistent with atypical carcinoid tumor of the larynx. A TORS-SL was performed. There was no recurrence during a follow-up period of 18 months. NETs of the larynx are a very heterogeneous group of tumors in terms of pathological features and biological behavior. The histological diagnosis is the most important step in the management of these tumors. Tumor histology is an important determinant of prognosis. TORS-SL is a promising, minimally invasive, endoscopic surgical alternative for the treatment of supraglottic tumors with good functional and clinical outcomes as seen in this case.


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