scholarly journals Synthesis and characterization of a magnetic hybrid catalyst containing lipase and palladium and its application on the dynamic kinetic resolution of amines

2020 ◽  
Vol 493 ◽  
pp. 111106 ◽  
Author(s):  
Clara A. Ferraz ◽  
Marcelo A. do Nascimento ◽  
Rhudson F.O. Almeida ◽  
Gabriella G. Sergio ◽  
Aldo A.T. Junior ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Synthesis And Characterization ◽  
Hybrid Catalyst ◽  
Dynamic Kinetic Resolution

Improved synthesis of Bn5CpRu(CO)2Cl and its application as racemization catalyst in preparative-scale metalloenzymatic dynamic kinetic resolution of 1-phenylethanol

2010 ◽  
Vol 83 (3) ◽  
pp. 479-487 ◽  
Author(s):  
Denys Mavrynsky ◽  
Liisa T. Kanerva ◽  
Reijo Sillanpää ◽  
Reko Leino
Keyword(s):  
Kinetic Resolution ◽  
Immobilized Enzyme ◽  
Metal Catalyst ◽  
Secondary Alcohols ◽  
Mass Loading ◽  
Dynamic Kinetic Resolution ◽  
Preparative Scale ◽  
Highly Active ◽  
Complex Forms

An improved gram-scale synthesis of Bn5CpRu(CO)2Cl is reported based on heating of pentabenzylcyclopentadiene with Ru3(CO)12 at 160 °C under argon atmosphere in mesitylene followed by addition of chloroform, continued heating, and evaporation of the solvents. Subsequent washing of unreacted ligand precursor with hexane provided pure title compound in 77 % yield. In combination with Candida antarctica lipase B (CAL-B) (Novozym 435), this complex forms a highly active racemization catalyst for metallo-enzymatic dynamic kinetic resolution (DKR) of secondary alcohols as demonstrated in the present work by converting 100 g of racemic 1-phenylethanol to (R)-1-phenylethanol in >99 % ee and 93 % overall yield over two steps using 0.05 mol % loading of the metal catalyst and 1 mass % loading of immobilized enzyme. In addition, the synthesis and crystallographic characterization of the palladium congener Bn5CpPd(PPh3)Cl are briefly discussed.

Synthesis and characterization of a novel polyoxometalate–Cu(II) hybrid catalyst for efficient synthesis of triazols

Polyhedron ◽  
2016 ◽  
Vol 115 ◽  
pp. 61-66 ◽  
Author(s):  
Ali Zarnegaryan ◽  
Majid Moghadam ◽  
Shahram Tangestaninejad ◽  
Valiollah Mirkhani ◽  
Iraj Mohammadpoor-Baltork
Keyword(s):  
Synthesis And Characterization ◽  
Efficient Synthesis ◽  
Hybrid Catalyst

Synthesis and Characterization of the Three Dicyclopentapyrenes

1996 ◽  
Vol 61 (10) ◽  
pp. 3572-3572
Author(s):  
Lawrence T. Scott ◽  
Atena Necula
Keyword(s):  
Synthesis And Characterization
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