scholarly journals Effects of soluble extracts from Leishmania infantum promastigotes, Toxoplasma gondii tachyzoites on TGF-β mediated pathways in activated CD4+ T lymphocytes

2014 ◽  
Vol 16 (9) ◽  
pp. 778-787 ◽  
Author(s):  
Ann Maria Clemente ◽  
Carlo Severini ◽  
Giuseppe Castronovo ◽  
Michele Tanturli ◽  
Eloisa Perissi ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
T Lymphocytes ◽  
Leishmania Infantum

Leishmania infantum and Toxoplasma gondii: Mixed infection of macrophages in vitro and in vivo

2011 ◽  
Vol 128 (3) ◽  
pp. 279-284 ◽  
Author(s):  
Vasiliki Christodoulou ◽  
Ippokratis Messaritakis ◽  
Eleni Svirinaki ◽  
Christos Tsatsanis ◽  
Maria Antoniou
Keyword(s):  
Toxoplasma Gondii ◽  
Mixed Infection ◽  
Leishmania Infantum

Kennel dogs as sentinels of Leishmania infantum, Toxoplasma gondii, and Neospora caninum in Majorca Island, Spain

2010 ◽  
Vol 107 (6) ◽  
pp. 1505-1508 ◽  
Author(s):  
Oscar Cabezón ◽  
Javier Millán ◽  
Margalida Gomis ◽  
Jitender P. Dubey ◽  
Ezio Ferroglio ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Leishmania Infantum ◽  
Neospora Caninum

scholarly journals Presence of antibodies against Toxoplasma gondii, Neospora caninum and Leishmania infantum in dogs from Piauí

2011 ◽  
Vol 20 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Marcos Gomes Lopes ◽  
Ivete Lopes Mendonça ◽  
Kleber Portela Fortes ◽  
Marcos Amaku ◽  
Hilda de Fátima Jesus Pena ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Leishmania Infantum ◽  
Neospora Caninum ◽  
Fluorescent Antibody ◽  
Northeastern Brazil ◽  
Leishmania Infection ◽  
Serum Samples ◽  
Chi Square ◽  
Leishmania Spp ◽  
And Gender

This study aimed to evaluate the presence of antibodies against Neospora caninum, Toxoplasma gondii and Leishmania infantum in dogs attended at the Veterinary Hospital of the Federal University of Piauí, Northeastern Brazil, where there are no reports of the occurrence of N. caninum and T. gondii in dogs. Serum samples from 530 dogs of genders, different ages and breeds from the municipality of Teresina and nearby towns were analyzed using three indirect fluorescent antibody tests, each one targeting one of the three agents. The associations between the parasites and gender, breed and age of the dogs were assessed by the chi-square test (p > 0.05). The occurrence of antibodies to N. caninum, T. gondii and L. infantum was 3.2, 18.0 and 78.1%, respectively. Toxoplasma gondii was more frequently found in older dogs (p < 0.05) whereas L. infantum was more common in animals aged between 1 to 3 years (p < 0.05). In order to evaluate potential associations between the presence of anti-N. caninum and anti-T. gondii antibodies and Leishmania infection, 240 dogs were selected (120 positive and 120 negative for Leishmania spp.), based on serological and parasitological diagnoses. No association was found between Leishmania spp. and the coccidian parasites (p > 0.05). The results confirm the exposure of dogs to these parasites in the State of Piauí.

scholarly journals Heat treatment alleviates the growth and photosynthetic impairment of transplastomic plants expressing Leishmania infantum Hsp83-Toxoplasma gondii SAG1 fusion protein

Plant Science ◽  
2019 ◽  
Vol 284 ◽  
pp. 117-126 ◽  
Author(s):  
Mariana G. Corigliano ◽  
Romina M. Albarracín ◽  
Juan M. Vilas ◽  
Edwin F. Sánchez López ◽  
Sofía A. Bengoa Luoni ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Toxoplasma Gondii ◽  
Fusion Protein ◽  
Leishmania Infantum ◽  
Transplastomic Plants

scholarly journals Human CD4+ and CD8+ T lymphocytes are both cytotoxic to Toxoplasma gondii-infected cells.

1996 ◽  
Vol 64 (1) ◽  
pp. 176-181 ◽  
Author(s):  
J G Montoya ◽  
K E Lowe ◽  
C Clayberger ◽  
D Moody ◽  
D Do ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
T Lymphocytes ◽  
Cd8 T Lymphocytes ◽  
Infected Cells

scholarly journals A Rapid Flow Cytometric Method to Explore Cellular Immunity against Toxoplasma gondii in Humans

1998 ◽  
Vol 5 (6) ◽  
pp. 745-748 ◽  
Author(s):  
Sandrine Kahi ◽  
Grégoire J. N. Cozon ◽  
Timothy Greenland ◽  
Martine Wallon ◽  
Françoise Gay-Andrieu ◽  
...  
Keyword(s):  
T Cells ◽  
Toxoplasma Gondii ◽  
T Lymphocytes ◽  
Congenital Infection ◽  
Cell Mediated Immunity ◽  
Flow Cytometric Method ◽  
Flow Cytometric ◽  
Excellent Candidate ◽  
Activation Antigens

ABSTRACT To assess cell-mediated immunity to Toxoplasma gondii, we evaluated the expression of the activation antigens CD69, CD71, and CD25 on T lymphocytes by flow cytometry after specific in vitro stimulation of whole blood from 127 T. gondii-positive and 63 T. gondii-negative patients. T lymphocytes from many seropositive individuals did not express CD69 at 24 h afterT. gondii antigen stimulation, but CD71 and CD25 were easily detectable on T cells from seropositive individuals 7 days after specific activation. CD25 was mainly expressed by stimulated CD4+ T cells, and its detection on total T cells was both a sensitive (98%) and a specific (97%) indicator of prior T. gondii infection. These results make flow cytometric detection of CD25 an excellent candidate for screening cell-mediated immunity toT. gondii in vitro and an interesting tool for the diagnosis of congenital infection.

scholarly journals Epitopes recognized by human T lymphocytes in the ROP2 protein antigen of Toxoplasma gondii.

1996 ◽  
Vol 64 (9) ◽  
pp. 3858-3862 ◽  
Author(s):  
R Saavedra ◽  
M A Becerril ◽  
C Dubeaux ◽  
R Lippens ◽  
M J De Vos ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
T Lymphocytes ◽  
Protein Antigen ◽  
Human T Lymphocytes

scholarly journals Seroprevalence of Toxoplasma gondii and Leishmania spp. in domestic donkeys from Portugal

2019 ◽  
Vol 28 (1) ◽  
pp. 172-176 ◽  
Author(s):  
Filipa Teixeira Rodrigues ◽  
Catarina Pereira ◽  
Jitender Prakash Dubey ◽  
Miguel Nóvoa ◽  
Miguel Quaresma ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
Leishmania Infantum ◽  
Agglutination Test ◽  
Direct Agglutination Test ◽  
Serum Samples ◽  
Modified Agglutination Test ◽  
Leishmania Spp

Abstract Toxoplasma gondii and Leishmania infantum are zoonotic protozoal parasites. Serum samples were obtained from 186 donkeys (Equus africanus asinus) from Portugal and assessed for antibodies to T. gondii by the modified agglutination test (MAT). For titration of antibodies to Leishmania spp. the direct agglutination test was used (DAT). Eleven donkeys were seropositive for T. gondii with titres of 20 (n = 7), 80 (n = 2), 640 (n = 1) and ≥ 2560 (n = 1). One donkey was seropositive for Leishmania spp. (titre of 800). Donkeys in Portugal are exposed to and can be infected with T. gondii and Leishmania spp.

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