In vitro and in vivo antifungal activity of Cassia surattensis flower against Aspergillus niger

2014 ◽  
Vol 77 ◽  
pp. 7-12 ◽  
Author(s):  
Vello Sumathy ◽  
Zuraini Zakaria ◽  
Subramanion L. Jothy ◽  
Sivapragasam Gothai ◽  
Soundararajan Vijayarathna ◽  
...  
Author(s):  
Janet Herrada ◽  
Ahmed Gamal ◽  
Lisa Long ◽  
Sonia P. Sanchez ◽  
Thomas S. McCormick ◽  
...  

Antifungal activity of AmBisome against Candida auris was determined in vitro and in vivo. AmBisome showed MIC50 and MIC90 values of 1 and 2 μg/mL, respectively. Unlike conventional amphotericin B, significant in vivo efficacy was observed in the AmBisome 7.5 mg/kg -treated group in survival and reduction of kidney tissue fungal burden compared to the untreated group. Our data shows that AmBisome shows significant antifungal activity against C. auris in vitro as well as in vivo.


2020 ◽  
Vol 154 ◽  
pp. 112745
Author(s):  
Qiong Yang ◽  
Jiao Wang ◽  
Peng Zhang ◽  
Shengnan Xie ◽  
Xiaolong Yuan ◽  
...  

2015 ◽  
pp. 1563-1570 ◽  
Author(s):  
Idriss Talibi ◽  
Latifa Askarne ◽  
Hassan Boubaker ◽  
El Hassane Boudyach ◽  
Abdellah Ait Ben Oumar

2013 ◽  
Vol 33 ◽  
pp. 40-46 ◽  
Author(s):  
Claudia Fieira ◽  
Francieli Oliveira ◽  
Rubens Perez Calegari ◽  
Alessandra Machado ◽  
Alexandre Rodrigo Coelho

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S471-S472
Author(s):  
Emily Larkin ◽  
Lisa Long ◽  
Christopher Hager ◽  
Karen Joy Shaw ◽  
Mahmoud Ghannoum

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Laila Muñoz Castellanos ◽  
Nubia Amaya Olivas ◽  
Juan Ayala-Soto ◽  
Carmen Miriam De La O Contreras ◽  
Miriam Zermeño Ortega ◽  
...  

In this study, hydrodistillation was used to obtain essential oils (EOs) from pepper (Piper nigrum L.) and clove (Eugenia caryophyllata) and co-hydrodistillation (addition of fatty acid ethyl esters as extraction co-solvents) was used to obtain functional extracts (FEs). Antifungal activity of EOs and FEs was evaluated by determination of minimum inhibitory concentration (MIC) against Fusarium oxysporum and Aspergillus niger. The results showed that pepper (Piper nigrum) and clove (Eugenia caryophyllata) essential oils and their functional extracts are effective in vitro at concentrations from 400 to 500 ppm after 10 days of culturing. The essential oils and functional extracts were used on tomato fruit samples at three different concentrations: 350, 400, and 450 ppm5. Clove essential oil reduced the growth of Aspergillus niger from 50% to 70% and Fusarium oxysporum to 40%. The functional extracts (FEs) of clove and pepper, mixed with ethyl decanoate (FEs-C10), were the best combination for protecting the tomato fruit in vivo against both phytopathogenic fungi. Gas chromatography-mass spectrometry (GC-MS) was used to identify eugenol as the principal compound in clove oil and limonene, sabinene, and β-caryophyllene in pepper oil.


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