Comparison of different cytotoxicity measurements for the in vitro micronucleus assay using L5178Y and TK6 cells in support of OECD draft Test Guideline 487

Elisabeth Lorge

doi:10.1016/j.mrgentox.2010.03.002

Comparison of different cytotoxicity measurements for the in vitro micronucleus assay using L5178Y and TK6 cells in support of OECD draft Test Guideline 487

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2010.03.002 ◽

2010 ◽

Vol 702 (2) ◽

pp. 199-207 ◽

Cited By ~ 15

Author(s):

Elisabeth Lorge

Keyword(s):

Micronucleus Assay ◽

Tk6 Cells ◽

In Vitro Micronucleus Assay ◽

Test Guideline

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Guidance for understanding solubility as a limiting factor for selecting the upper test concentration in the OECD In Vitro Micronucleus Assay Test Guideline No. 487

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2011.03.007 ◽

2011 ◽

Vol 722 (1) ◽

pp. 89-90 ◽

Cited By ~ 2

Author(s):

Marilyn J. Aardema ◽

Sheila Galloway ◽

Errol Zeiger ◽

Michael C. Cimino ◽

Makoto Hayashi

Keyword(s):

Micronucleus Assay ◽

Limiting Factor ◽

Test Concentration ◽

In Vitro Micronucleus Assay ◽

Test Guideline

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Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment

Environmental and Molecular Mutagenesis ◽

10.1002/em.21760 ◽

2013 ◽

Vol 54 (3) ◽

pp. 180-194 ◽

Cited By ~ 20

Author(s):

Steven M. Bryce ◽

Svetlana L. Avlasevich ◽

Jeffrey C. Bemis ◽

Matthew Tate ◽

Richard M. Walmsley ◽

...

Keyword(s):

Micronucleus Assay ◽

Flow Cytometric ◽

Protocol Optimization ◽

Tk6 Cells ◽

In Vitro Micronucleus Assay

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Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2017.10.006 ◽

2018 ◽

Vol 825 ◽

pp. 40-50 ◽

Cited By ~ 5

Author(s):

David P. Lovell ◽

Mick Fellows ◽

Francesco Marchetti ◽

Joan Christiansen ◽

Azeddine Elhajouji ◽

...

Keyword(s):

Micronucleus Assay ◽

Historical Control Group ◽

Historical Control ◽

Control Group ◽

Group Data ◽

Tk6 Cells ◽

In Vitro Micronucleus Assay

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Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2010.04.005 ◽

2010 ◽

Vol 702 (2) ◽

pp. 148-156 ◽

Cited By ~ 7

Author(s):

Olivier Cariou ◽

Nathalie Laroche-Prigent ◽

Sandrine Ledieu ◽

Isabelle Guizon ◽

Françoise Paillard ◽

...

Keyword(s):

Mammalian Cell ◽

Cytosine Arabinoside ◽

Micronucleus Test ◽

Micronucleus Assay ◽

Mouse Lymphoma Cells ◽

In Vitro Micronucleus Assay ◽

Test Guideline ◽

Mouse Lymphoma ◽

Oecd Test Guideline

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A flow cytometry based in vitro micronucleus assay in TK6 cells-Validation using early stage pharmaceutical development compounds

Environmental and Molecular Mutagenesis ◽

10.1002/em.20632 ◽

2010 ◽

Vol 52 (5) ◽

pp. 363-372 ◽

Cited By ~ 17

Author(s):

Magdalena Lukamowicz ◽

Katherine Woodward ◽

Micheline Kirsch-Volders ◽

Willi Suter ◽

Azeddine Elhajouji

Keyword(s):

Flow Cytometry ◽

Early Stage ◽

Micronucleus Assay ◽

Pharmaceutical Development ◽

Tk6 Cells ◽

In Vitro Micronucleus Assay

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Validation of a high throughput flow cytometric in vitro micronucleus assay including assessment of metabolic activation in TK6 cells

Environmental and Molecular Mutagenesis ◽

10.1002/em.21891 ◽

2014 ◽

Vol 55 (9) ◽

pp. 704-718 ◽

Cited By ~ 9

Author(s):

Annemette V. Thougaard ◽

Joan Christiansen ◽

Tomas Mow ◽

Jorrit J. Hornberg

Keyword(s):

High Throughput ◽

Micronucleus Assay ◽

Metabolic Activation ◽

Flow Cytometric ◽

Tk6 Cells ◽

In Vitro Micronucleus Assay

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Development and validation of an in vitro micronucleus assay platform in TK6 cells

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2012.02.005 ◽

2012 ◽

Vol 746 (1) ◽

pp. 29-34 ◽

Cited By ~ 18

Author(s):

Zhanna Sobol ◽

Michael L. Homiski ◽

Donna A. Dickinson ◽

Richard A. Spellman ◽

Dingzhou Li ◽

...

Keyword(s):

Micronucleus Assay ◽

Tk6 Cells ◽

Development And Validation ◽

In Vitro Micronucleus Assay

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The In Vitro Micronucleus Assay

Methods in Molecular Biology - Genetic Toxicology ◽

10.1007/978-1-61779-421-6_7 ◽

2011 ◽

pp. 121-141 ◽

Cited By ~ 18

Author(s):

Ann T. Doherty

Keyword(s):

Micronucleus Assay ◽

In Vitro Micronucleus Assay

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Determination of Clastogenic and Anticlastogenic Potential of Cuminum Cyminum Seed Oil Using in Vitro Micronucleus Assay in CHO-K1 Cells

Journal of Herbs Spices & Medicinal Plants ◽

10.1080/10496475.2019.1602574 ◽

2019 ◽

Vol 25 (3) ◽

pp. 259-270

Author(s):

Vinod Kumar Goyal ◽

Sthevaan Vincent ◽

Santosh Kumar Pandey ◽

Ramakrishna Nirogi

Keyword(s):

Seed Oil ◽

Micronucleus Assay ◽

Cuminum Cyminum ◽

In Vitro Micronucleus Assay

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Performance of the flow cytometry-based in vitro micronucleus assay in a validation study

Toxicology Letters ◽

10.1016/j.toxlet.2016.06.2078 ◽

2016 ◽

Vol 258 ◽

pp. S316

Author(s):

D.J. Smart ◽

F. Helbling ◽

P. Blandine ◽

M. Damian ◽

V. Patrick

Keyword(s):

Flow Cytometry ◽

Validation Study ◽

Micronucleus Assay ◽

In Vitro Micronucleus Assay

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