Development and validation of an in vitro micronucleus assay platform in TK6 cells

2012 ◽  
Vol 746 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Zhanna Sobol ◽  
Michael L. Homiski ◽  
Donna A. Dickinson ◽  
Richard A. Spellman ◽  
Dingzhou Li ◽  
...  
Keyword(s):  
Micronucleus Assay ◽  
Tk6 Cells ◽  
Development And Validation ◽  
In Vitro Micronucleus Assay

Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment

2013 ◽  
Vol 54 (3) ◽  
pp. 180-194 ◽  
Author(s):  
Steven M. Bryce ◽  
Svetlana L. Avlasevich ◽  
Jeffrey C. Bemis ◽  
Matthew Tate ◽  
Richard M. Walmsley ◽  
...  
Keyword(s):  
Micronucleus Assay ◽  
Flow Cytometric ◽  
Protocol Optimization ◽  
Tk6 Cells ◽  
In Vitro Micronucleus Assay

scholarly journals Analysis of negative historical control group data from the in vitro micronucleus assay using TK6 cells

2018 ◽  
Vol 825 ◽  
pp. 40-50 ◽  
Author(s):  
David P. Lovell ◽  
Mick Fellows ◽  
Francesco Marchetti ◽  
Joan Christiansen ◽  
Azeddine Elhajouji ◽  
...  
Keyword(s):  
Micronucleus Assay ◽  
Historical Control Group ◽  
Historical Control ◽  
Control Group ◽  
Group Data ◽  
Tk6 Cells ◽  
In Vitro Micronucleus Assay

A flow cytometry based in vitro micronucleus assay in TK6 cells-Validation using early stage pharmaceutical development compounds

2010 ◽  
Vol 52 (5) ◽  
pp. 363-372 ◽  
Author(s):  
Magdalena Lukamowicz ◽  
Katherine Woodward ◽  
Micheline Kirsch-Volders ◽  
Willi Suter ◽  
Azeddine Elhajouji
Keyword(s):  
Flow Cytometry ◽  
Early Stage ◽  
Micronucleus Assay ◽  
Pharmaceutical Development ◽  
Tk6 Cells ◽  
In Vitro Micronucleus Assay

Performance of the flow cytometry-based in vitro micronucleus assay in a validation study

2016 ◽  
Vol 258 ◽  
pp. S316
Author(s):  
D.J. Smart ◽  
F. Helbling ◽  
P. Blandine ◽  
M. Damian ◽  
V. Patrick
Keyword(s):  
Flow Cytometry ◽  
Validation Study ◽  
Micronucleus Assay ◽  
In Vitro Micronucleus Assay
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