In vivo genotoxicity of 1,4-dioxane evaluated by liver and bone marrow micronucleus tests and Pig-a assay in rats

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/j.mrgentox.2018.09.004 ◽

2019 ◽

Vol 837 ◽

pp. 8-14 ◽

Author(s):

Satoru Itoh ◽

Chiharu Hattori

Keyword(s):

Bone Marrow ◽

Micronucleus Tests ◽

Bone Marrow Micronucleus

Download Full-text

Estimation of the non-genotoxic effect level in vivo in bone marrow micronucleus tests for a rare disease drug candidate

Toxicology Letters ◽

10.1016/j.toxlet.2018.06.746 ◽

2018 ◽

Vol 295 ◽

pp. S149

Author(s):

L. Mueller ◽

A. Zeller ◽

M. Guerard ◽

A. Poirier

Keyword(s):

Bone Marrow ◽

Rare Disease ◽

Genotoxic Effect ◽

Drug Candidate ◽

Micronucleus Tests ◽

Effect Level ◽

Bone Marrow Micronucleus

Download Full-text

Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays

Environmental and Molecular Mutagenesis ◽

10.1002/(sici)1098-2280(1996)28:1<60::aid-em9>3.0.co;2-i ◽

1996 ◽

Vol 28 (1) ◽

pp. 60-63 ◽

Author(s):

Jon C. Mirsalis ◽

Carol M. Hamilton ◽

Kathleen G. O'Loughlin ◽

Dennis J. Paustenbach ◽

Brent D. Kerger ◽

...

Keyword(s):

Bone Marrow ◽

Drinking Water ◽

Dna Synthesis ◽

Unscheduled Dna Synthesis ◽

Chromium Vi ◽

Bone Marrow Micronucleus

Download Full-text

Investigating the Relationship between in Vitro–in Vivo Genotoxicity: Derivation of Mechanistic QSAR Models for in Vivo Liver Genotoxicity and in Vivo Bone Marrow Micronucleus Formation Which Encompass Metabolism

Chemical Research in Toxicology ◽

10.1021/tx200547s ◽

2012 ◽

Vol 25 (2) ◽

pp. 277-296 ◽

Author(s):

Ovanes G. Mekenyan ◽

Petko I. Petkov ◽

Stefan V. Kotov ◽

Stoyanka Stoeva ◽

Verginia B. Kamenska ◽

...

Keyword(s):

Bone Marrow ◽

Micronucleus Formation ◽

Qsar Models ◽

The Relationship ◽

Bone Marrow Micronucleus

Download Full-text

Genotoxicity assessment of S-equol in bacterial mutation, chromosomal aberration, and rodent bone marrow micronucleus tests

Food and Chemical Toxicology ◽

10.1016/j.fct.2010.09.027 ◽

2010 ◽

Vol 48 (12) ◽

pp. 3481-3485 ◽

Author(s):

Richard Schwen ◽

Richard Jackson ◽

Raymond Proudlock

Keyword(s):

Bone Marrow ◽

Chromosomal Aberration ◽

Micronucleus Tests ◽

Bacterial Mutation ◽

Bone Marrow Micronucleus

Download Full-text

In vivo genotoxicity of selected herbicides in the mouse bone-marrow micronucleus test

Archives of Toxicology ◽

10.1007/s002040050375 ◽

1997 ◽

Vol 71 (3) ◽

pp. 193-197 ◽

Author(s):

T. Gebel ◽

S. Kevekordes ◽

K. Pav ◽

R. Edenharder ◽

H. Dunkelberg

Keyword(s):

Bone Marrow ◽

Micronucleus Test ◽

Mouse Bone Marrow ◽

Bone Marrow Micronucleus

Download Full-text

Comparative in-vivo genotoxicity of antiviral nucleoside analogues; penciclovir, acyclovir, ganciclovir and the xanthine analogue, caffeine, in the mouse bone marrow micronucleus assay

Mutation Research/Genetic Toxicology ◽

10.1016/s0165-1218(96)90049-x ◽

1996 ◽

Vol 369 (1-2) ◽

pp. 65-74 ◽

Author(s):

P. Haynes ◽

T.R. Lambert ◽

I. de G. Mitchell

Keyword(s):

Bone Marrow ◽

Micronucleus Assay ◽

Nucleoside Analogues ◽

Mouse Bone Marrow ◽

Antiviral Nucleoside ◽

Bone Marrow Micronucleus

Download Full-text

Studies for a genotoxic potential of some endogenous and exogenous sex steroids. II. communication: Examination for the induction of cytogenetic damage using the chromosomal aberration assay on human lymphocytes in vitro and the mouse bone marrow micronucleus test in vivo

Environmental and Molecular Mutagenesis ◽

10.1002/(sici)1098-2280(1996)28:2<133::aid-em10>3.0.co;2-g ◽

1996 ◽

Vol 28 (2) ◽

pp. 133-144 ◽

Author(s):

Roland Reimann ◽

Sabine Kalweit ◽

Rainer Lang

Keyword(s):

Bone Marrow ◽

Chromosomal Aberration ◽

Sex Steroids ◽

Micronucleus Test ◽

Human Lymphocytes ◽

Mouse Bone Marrow ◽

Chromosomal Aberration Assay ◽

Bone Marrow Micronucleus

Download Full-text

The influence of automobile exhausts on mutagenicity of soils: contamination with, fractionation, separation, and preliminary identification of mutagens in the Salmonella/reversion assay and effects of solvent fractions on the sister-chromatid exchanges in human lymphocyte cultures and in the in vivo mouse bone marrow micronucleus assay

Mutation Research/Genetic Toxicology and Environmental Mutagenesis ◽

10.1016/s1383-5718(00)00088-7 ◽

2000 ◽

Vol 472 (1-2) ◽

pp. 1-21 ◽

Author(s):

H.F. Wesp ◽

X. Tang ◽

R. Edenharder

Keyword(s):

Bone Marrow ◽

Human Lymphocyte ◽

Micronucleus Assay ◽

Sister Chromatid Exchanges ◽

Mouse Bone Marrow ◽

Preliminary Identification ◽

Lymphocyte Cultures ◽

Chromatid Exchanges ◽

Bone Marrow Micronucleus

Download Full-text

551 Genotoxic potency of the combination of carbendazim and captan formulations and their interaction, determined by the in vivo bone marrow micronucleus test

Toxicology Letters ◽

10.1016/s0378-4274(03)90550-9 ◽

2003 ◽

Vol 144 ◽

pp. s148

Author(s):

M. Goumenou ◽

K. Machera

Keyword(s):

Bone Marrow ◽

Micronucleus Test ◽

Genotoxic Potency ◽

Bone Marrow Micronucleus

Download Full-text

Prior bleeding enhances the sensitivity of peripheral blood and bone marrow micronucleus tests in rats

Mutagenesis ◽

10.1093/mutage/gem015 ◽

2007 ◽

Vol 22 (4) ◽

pp. 287-291 ◽

Author(s):

A. Vikram ◽

P. Ramarao ◽

G. Jena

Keyword(s):

Bone Marrow ◽

Peripheral Blood ◽

Micronucleus Tests ◽

Bone Marrow Micronucleus

Download Full-text