scholarly journals Comparison of brain and spinal cord magnetic resonance imaging features in neuromyelitis optica spectrum disorders patients with or without aquaporin-4 antibody

2017 ◽  
Vol 13 ◽  
pp. 58-66 ◽  
Author(s):  
Moli Fan ◽  
Ying Fu ◽  
Lei Su ◽  
Yi Shen ◽  
Kristofer Wood ◽  
...  
2014 ◽  
Vol 20 (10) ◽  
pp. 1407-1408 ◽  
Author(s):  
H Okuma ◽  
K Matsumura ◽  
Y Hatanaka ◽  
F Saito ◽  
M Sonoo

We report a patient with neuromyelitis optica spectrum disorders who presented with sudden onset of sleep as the sole manifestation. Magnetic resonance imaging investigation revealed lesions in the hypothalamus bilaterally, which vanished completely after methylprednisolone pulse therapy.


2018 ◽  
Vol 20 (3) ◽  
pp. 142-144 ◽  
Author(s):  
Sarah Kariv ◽  
Kathleen Bateman

A 17-year-old girl presented with intractable vomiting due to area postrema involvement in the first presentation of seronegative neuromyelitis optica (NMO). During the course of her illness, she developed mild hyponatremia, and magnetic resonance imaging revealed abnormalities consistent with the co-occurrence of osmotic demyelination syndrome (ODS). This combination of imaging features is novel, and this case expands the spectrum of brain abnormalities seen in NMO and NMO spectrum disorders. It was suspected that NMO may predispose to ODS by causing astrocyte dysfunction involving aquaporin 4 water channels, which are implicated in both conditions.


2018 ◽  
Author(s):  
Jeong Yeon Kim

The term Neuromyelitis optica spectrum disorder (NMOSD) is a recently proposed for neuromyelitis optica and related syndromes. Along with serum anti-aquaporin 4 antibody status, detection of a lesions extending over ≥3 contiguous spinal cord segments (longitudinally extensive transverse myelitis, LETM) associated with acute myelitis is the most specific neuroimaging characteristic of NMOSD. 1 We present a case of NMOSD with delayed lesion on spinal cord magnetic resonance imaging.


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