Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes

Lewy Bodies ◽

Metabotropic glutamate receptor 5 knockout reduces cognitive impairment and pathogenesis in a mouse model of Alzheimer's disease

Molecular Brain ◽

10.1186/1756-6606-7-40 ◽

2014 ◽

Vol 7 (1) ◽

pp. 40 ◽

Cited By ~ 67

Author(s):

Alison Hamilton ◽

Jessica L Esseltine ◽

Rebecca A DeVries ◽

Sean P Cregan ◽

Stephen S G Ferguson

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Cognitive Impairment ◽

Mouse Model ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

Model Of Alzheimer’S Disease

P2-022: Declines of hippocampal metabotropic glutamate receptor in Alzheimer's disease

10.1016/j.jalz.2009.04.331 ◽

2009 ◽

Vol 5 (4S_Part_9) ◽

pp. P267-P267

Author(s):

Luciano Minuzzi ◽

Remi Quirion ◽

Serge Gauthier ◽

Pedro Rosa-Neto

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutamate Receptor ◽

Abnormal Metabotropic Glutamate Receptor Expression and Signaling in the Cerebral Cortex in Diffuse Lewy Body Disease is Associated with Irregular α-Synuclein/Phospholipase C (PLCβ1) Interactions

Brain Pathology ◽

10.1111/j.1750-3639.2004.tb00082.x ◽

2006 ◽

Vol 14 (4) ◽

pp. 388-398 ◽

Cited By ~ 51

Author(s):

E. Dalfó ◽

J. L. Albasanz ◽

M. Martín ◽

I. Ferrer

Keyword(s):

Cerebral Cortex ◽

Phospholipase C ◽

Glutamate Receptor ◽

Lewy Body ◽

Lewy Body Disease ◽

Receptor Expression ◽

Diffuse Lewy Body Disease ◽

IC-04-03: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE

10.1016/j.jalz.2018.06.2051 ◽

2006 ◽

Vol 14 (7S_Part_1) ◽

pp. P8-P9

Author(s):

Adam P. Mecca ◽

Julia W. McDonald ◽

Hannah R. Michalak ◽

Tyler Godek ◽

Joanna Harris ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutamate Receptor ◽

Pet Imaging ◽

Metabotropic Glutamate Receptor 5 ◽

Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease

Journal of Neurochemistry ◽

10.1111/jnc.12296 ◽

2013 ◽

Vol 127 (3) ◽

pp. 415-425 ◽

Cited By ~ 27

Author(s):

Valeriy G. Ostapchenko ◽

Flavio H. Beraldo ◽

Andre L. S. Guimarães ◽

Sanju Mishra ◽

Monica Guzman ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Prion Protein ◽

Glutamate Receptor ◽

Protein Processing ◽

Metabotropic Glutamate ◽

Model Of Alzheimer’S Disease ◽

Metabotropic Glutamate Receptor 1

P1-469: PET IMAGING OF METABOTROPIC GLUTAMATE RECEPTOR 5 BINDING IN ALZHEIMER'S DISEASE

10.1016/j.jalz.2018.06.479 ◽

2006 ◽

Vol 14 (7S_Part_9) ◽

pp. P501-P503 ◽

Cited By ~ 1

Author(s):

Adam P. Mecca ◽

Julia W. McDonald ◽

Hannah R. Michalak ◽

Tyler Godek ◽

Joanna Harris ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutamate Receptor ◽

Pet Imaging ◽

Metabotropic Glutamate Receptor 5 ◽

DT-02-05: In vivo characterization of metabotropic glutamate receptor type five vulnerability in behavioral variant FTD and Alzheimer's disease: An [11 C]ABP688 PET/ VBM /DBM study

10.1016/j.jalz.2013.08.012 ◽

2013 ◽

Vol 9 ◽

pp. P846-P846

Author(s):

Antoine Leuzy ◽

Jared Rowley ◽

Pedro Rosa-Neto ◽

Serge Gauthier

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutamate Receptor ◽

Receptor Type ◽

Metabotropic Glutamate ◽

In Vivo Characterization

Brain 11 C‐ITMM PET to longitudinally assess type 1 metabotropic glutamate receptor availability in Alzheimer's disease

Journal of Neuroimaging ◽

10.1111/jon.12895 ◽

2021 ◽

Author(s):

Kenji Ishibashi ◽

Yoshiharu Miura ◽

Kei Wagatsuma ◽

Masashi Kameyama ◽

Kenji Ishii

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glutamate Receptor ◽

Metabotropic glutamate receptor/phospholipase C pathway: A vulnerable target to Creutzfeldt-Jakob disease in the cerebral cortex

Neuroscience ◽

10.1016/j.neuroscience.2004.12.023 ◽

2005 ◽

Vol 131 (4) ◽

pp. 825-832 ◽

Cited By ~ 14

Author(s):

A. Rodríguez ◽

M. Freixes ◽

E. Dalfó ◽

M. Martín ◽

B. Puig ◽

...

Keyword(s):

Cerebral Cortex ◽

Phospholipase C ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Jakob Disease

Assessment of the integrity of metabotropic glutamate receptor binding and its functional coupling to G proteins in human brain and in Alzheimer's disease

Biochemical Society Transactions ◽

10.1042/bst028a035b ◽

2000 ◽

Vol 28 (1) ◽

pp. A35-A35

Author(s):

Carol Shanahan ◽

Cora O'Neill

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Human Brain ◽

G Proteins ◽

Glutamate Receptor ◽

Receptor Binding ◽

Functional Coupling ◽