scholarly journals The CB1 antagonist, SR141716A, is protective in permanent photothrombotic cerebral ischemia

2016 ◽  
Vol 630 ◽  
pp. 9-15 ◽  
Author(s):  
Zachary Wilmer Reichenbach ◽  
Hongbo Li ◽  
Sara Jane Ward ◽  
Ronald F. Tuma
Keyword(s):  
Cerebral Ischemia ◽  
Cb1 Antagonist

Ultrastorcture of Cerebellar Purkinje Cells in Rats Subjected To Partial Global Cerebral Ischemia

1985 ◽  
Vol 43 ◽  
pp. 674-675
Author(s):  
R.V.W. Dimlich ◽  
M.H. Biros
Keyword(s):  
Cerebral Ischemia ◽  
Purkinje Cells ◽  
Cell Types ◽  
Microscopic Level ◽  
Global Cerebral Ischemia ◽  
Light Microscopic Level ◽  
Cerebellar Damage ◽  
Cerebellar Injury ◽  
Cerebellar Purkinje Cells ◽  
Cell Changes

In severe cerebral ischemia, Purkinje cells of the cerebellum are one of the cell types most vulnerable to anoxic damage. In the partial (forebrain) global ischemic (PGI) model of the rat, Paljärvi noted at the light microscopic level that cerebellar damage is inconsistant and when present, milder than in the telencephalon, diencephalon and rostral brain stem. Cerebellar injury was observed in 3 of 4 PGI rats following 5 minutes of reperfusion but in none of the rats after 90 min of reperfusion. To evaluate a time between these two extremes (5 and 90 min), the present investigation used the PGI model to study the effects of ischemia on the ultrastructure of cerebellar Purkinje cells in rats that were sacrificed after 30 min of reperfusion. This time also was chosen because lactic acid that is thought to contribute to ischemic cell changes in PGI is at a maximum after 30 min of reperfusion.

PPAR-γ agonist rosiglitazone decreases focal cerebral ischemia-induced inflammation and brain damage in adult mice

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S94-S94
Author(s):  
Kudret Tureyen ◽  
Ramya Sundaresan ◽  
Kellie Bowen ◽  
Raghu Vemuganti
Keyword(s):  
Cerebral Ischemia ◽  
Brain Damage ◽  
Focal Cerebral Ischemia ◽  
Adult Mice ◽  
Ppar Γ

Negative neurovascular coupling during anoxic depolarization and peri-infarct spreading depressions in acute focal cerebral ischemia in mice

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S425-S425
Author(s):  
Cenk Ayata ◽  
Hwa Kyoung Shin ◽  
Phillip Jones ◽  
Andrew K Dunn ◽  
David A Boas ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
Focal Cerebral Ischemia ◽  
Neurovascular Coupling ◽  
Anoxic Depolarization

Endocytosis and autophagy in cerebral ischemia and excitotoxicity

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S461-S461 ◽  
Author(s):  
Anne Vaslin ◽  
Julien Puyal ◽  
Vanessa Waechter ◽  
Tiziana Borsello ◽  
Peter G H Clarke
Keyword(s):  
Cerebral Ischemia

Central role of neuronal IkappaBalpha kinase (IKK) in cerebral ischemia

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S458-S458
Author(s):  
Oliver Herrmann ◽  
Rossanna de Lorenzi ◽  
Sajjad Muhammad ◽  
Wen Zhang ◽  
Martin Koehrmann ◽  
...  
Keyword(s):  
Cerebral Ischemia
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