Interactions between prelimbic cortex and basolateral amygdala contribute to morphine-induced conditioned taste aversion in conditioning and extinction

2020 ◽  
Vol 172 ◽  
pp. 107248
Author(s):  
Andrew Chih Wei Huang ◽  
Ying Hao Yu ◽  
Alan Bo Han He ◽  
Chen Yin Ou
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Basolateral Amygdala ◽  
Prelimbic Cortex

Overlapping memory trace indispensable for linking, but not recalling, individual memories

Science ◽  
2017 ◽  
Vol 355 (6323) ◽  
pp. 398-403 ◽  
Author(s):  
Jun Yokose ◽  
Reiko Okubo-Suzuki ◽  
Masanori Nomoto ◽  
Noriaki Ohkawa ◽  
Hirofumi Nishizono ◽  
...  
Keyword(s):  
Conditioned Stimulus ◽  
Fear Conditioning ◽  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Conditioned Response ◽  
Basolateral Amygdala ◽  
Memory Trace ◽  
Small Population ◽  
Associative Networks ◽  
Neuronal Ensemble

Memories are not stored in isolation from other memories but are integrated into associative networks. However, the mechanisms underlying memory association remain elusive. Using two amygdala-dependent behavioral paradigms—conditioned taste aversion (CTA) and auditory-cued fear conditioning (AFC)—in mice, we found that presenting the conditioned stimulus used for the CTA task triggered the conditioned response of the AFC task after natural coreactivation of the memories. This was accompanied through an increase in the overlapping neuronal ensemble in the basolateral amygdala. Silencing of the overlapping ensemble suppressed CTA retrieval-induced freezing. However, retrieval of the original CTA or AFC memory was not affected. A small population of coshared neurons thus mediates the link between memories. They are not necessary for recalling individual memories.

Activation of efferents from the basolateral amygdala during the retrieval of conditioned taste aversion

2013 ◽  
Vol 106 ◽  
pp. 210-220 ◽  
Author(s):  
Tadashi Inui ◽  
Chizuko Inui-Yamamoto ◽  
Yoshichika Yoshioka ◽  
Izumi Ohzawa ◽  
Tsuyoshi Shimura
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Basolateral Amygdala

Effects of Bilateral Amygdala Lesions on Neophobia and Conditioned Taste Aversion in Mice

1982 ◽  
Vol 54 (1) ◽  
pp. 127-130 ◽  
Author(s):  
Satoshi Shimai ◽  
Keiichiro Hoshishima
Keyword(s):  
Taste Aversion ◽  
Conditioned Taste Aversion ◽  
Basolateral Amygdala ◽  
Saccharine Solution ◽  
Amygdala Lesions ◽  
Bilateral Lesions ◽  
Gustatory Information

The effects of bilateral lesions of the basolateral amygdala on the neophobia to a novel solution and on the conditioned taste aversion were investigated in 35 male CFW mice. Analysis of consumed saccharine solution showed that the amygdala lesions in mice diminished the neophobia and conditioned taste aversion. These findings were consistent with previous data from rats and suggested that amygdala is an important area for processing gustatory information in mice.

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