Orbital giant conjunctival epithelial primary cyst

Author(s):  
F.J. Guijarro-Oria ◽  
E. Mencía-Gutiérrez ◽  
E. Gutiérrez-Díaz ◽  
E. López-Tizón
Keyword(s):  
1991 ◽  
Vol 84 (4) ◽  
pp. 459-553
Author(s):  
Yasushi Ohta ◽  
Hiroaki Funai ◽  
Bunji Tajima
Keyword(s):  

1982 ◽  
Vol 60 (5) ◽  
pp. 881-888 ◽  
Author(s):  
Clarence A. Speer ◽  
J. P. Dubey

Sarcocystis wapiti sp. nov. (Eimeriina: Sarcocystidae) is described as a heteroxenous coccidian with dogs (Canis familiaris) and coyotes (Canis latrans) as the final hosts and wapiti (Cervus elaphus) as the natural intermediate host. Sarcocysts in various muscle tissues of the wapiti were micro- to macroscopic, had a thin primary cyst wall and septa, and measured 652 × 322 μm. Sarcocysts contained numerous bradyzoites that were 16.1 × 2.4 μm and few metrocytes that were 11.2 × 4.6 μm. Ten days after ingesting Sarcocystis-infected wapiti meat, a dog and a coyote began passing oocysts and sporocysts in their feces; a domestic cat did not pass oocysts or sporocysts after ingesting infected meat from the same animal. Sporulated oocysts measured 20.3 × 15.6 μm; sporocysts were 15.9 × 10.6 μm. Twelve days after ingesting wapiti meat, oocysts of S. wapiti were found in the lamina propria of the distal one-third of the villi of the small intestine of the coyote. Bradyzoites were found in digests of muscle tissue of 58 of 65 wapiti.


1988 ◽  
Vol 66 (10) ◽  
pp. 2118-2121 ◽  
Author(s):  
Rolando H. Espinosa ◽  
Mauritz C. Sterner ◽  
John A. Blixt ◽  
Richard J. Cawthorn

Sporocysts of Sarcocystis were recovered from the intestinal mucosa of a northern saw-whet owl (Aegolius acadicus). Sporocysts measured 12.0 × 9.7 μm (9.6–14.0 × 8.0–12.0 μm; n = 100). Doses of 0, 500, and 2500 sporocysts were administered orally to five deer mice (Peromyscus maniculatus) and five Swiss-Cox white mice (Mus musculus) At necropsy, 28 days postinoculation, deer mice administered 500 and 2500 sporocysts had sarcocysts in skeletal muscles and cardiac muscle. White mice were negative at all dose levels. Sarcocysts had a thin wall (< 1 μm) that consisted of a primary cyst wall and a coarse granular layer composed of 36.6 nm granules (25.6–51.2 nm; n = 11). Thickness of the primary cyst wall was 62.5 nm (38.4–116.1 nm; n = 10). Metrocytes were 2.3 × 1.7 μm (1.5–3.5 × 1.2–2.5 μm; n = 25). Bradyzoites were 5.2 × 1.1 μm (4–7 × 1–2 μm; n = 25).


2021 ◽  
Author(s):  
shigehiro enkai ◽  
Hirokazu Kouguchi ◽  
Daniel Ken Inaoka ◽  
Takao Irie ◽  
Kinpei Yagi ◽  
...  

Abstract Purpose Alveolar echinococcosis (AE) is caused by the larval stage of Echinococcus multilocularis. Chemotherapy for AE involves albendazole (ABZ), which has shown insufficient efficacy. More effective chemotherapy for AE is needed. Previously, we have demonstrated that atovaquone (ATV), an anti-malarial, inhibits mitochondrial complex III of E. multilocularis and restricts the development of larval cysts in in vivo experiments. Therefore, in this study, we evaluated the efficacy of ABZ and ATV combination therapy on E. multilocularis in culture and in vivo experiments. Methods Protoscoleces were treated with 50 µM ABZ and/or ATV in the medium; the duration of parasite elimination was determined under aerobic and anaerobic culture. In the in vivo experiment, the effects of ABZ and ATV combination treatment in BALB/c mice infected orally with eggs from the feces of an adult-stage E. multilocularis-infected dog were compared with those of standard oral ABZ therapy. Results In the culture assay, the duration of elimination associated with ABZ and ATV combination treatment was 1 day shorter than that associated with ATV alone under aerobic conditions. Protoscolex viability progressively reduced owing to the combination treatment under anaerobic conditions; however, either drug used singly did not exhibit antiparasitic effects under hypoxia. Furthermore, compared with ABZ alone, the combination treatment significantly reduced the growth of the primary cyst in the liver of mice infected orally with parasite eggs. Conclusion ATV enhanced the effect of ABZ in the treatment of AE in mice.


2016 ◽  
pp. 2250-2253
Author(s):  
Heinz Mehlhorn
Keyword(s):  

1947 ◽  
Vol 73 (3) ◽  
pp. 320-325 ◽  
Author(s):  
Mario A. Castallo ◽  
Basil J. Giletto
Keyword(s):  

1978 ◽  
Vol 56 (11) ◽  
pp. 1309-1314 ◽  
Author(s):  
E. Schnepf ◽  
G. Deichgräber ◽  
G. Drebes

The primary zoospores of Lagenisma contain many peripheral "encystment vesicles." They disappear when the primary cyst wall is formed. The primary cyst wall consists of a 6-nm-thick, electron-dense layer and is secreted in less than 1 s. Ten seconds later, the flagella are retracted in the "straight-in way" within 3–4 s. The cyst bears spines which initially are filled with cytoplasm. They do not seem to contain cytoskeletal elements and possibly are shaped by a locally restricted extension of the cytoplasm and the cyst wall when the latter is formed. Later on, a secondary, inner, thicker fibrillar cyst wall layer is secreted. In contrast with other developmental stages studied hitherto, the vegetative primary cyst contains microbody-like structures.


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