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A Small Molecule Inhibitor, OGP46, Is Effective against Imatinib-Resistant BCR-ABL Mutations via the BCR-ABL/JAK-STAT Pathway
Molecular Therapy — Oncolytics
◽
10.1016/j.omto.2020.06.008
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2020
◽
Vol 18
◽
pp. 137-148
Author(s):
Liuya Wei
◽
Yang Yang
◽
Pranav Gupta
◽
Aihong Wang
◽
Min Zhao
◽
...
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Imatinib Resistant
◽
Molecule Inhibitor
◽
Stat Pathway
Download Full-text
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Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis
Bioorganic & Medicinal Chemistry Letters
◽
10.1016/j.bmcl.2010.08.019
◽
2010
◽
Vol 20
(20)
◽
pp. 6133-6137
◽
Cited By ~ 51
Author(s):
Valentina Corradi
◽
Manuela Mancini
◽
Fabrizio Manetti
◽
Sara Petta
◽
Maria Alessandra Santucci
◽
...
Keyword(s):
Small Molecule
◽
Protein Interactions
◽
Small Molecule Inhibitor
◽
Leukemia Cells
◽
Protein Protein Interactions
◽
Imatinib Resistant
◽
Molecule Inhibitor
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Faculty Opinions recommendation of Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1021658.247635
◽
2004
◽
Author(s):
William Kaelin
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Shh Pathway
◽
Molecule Inhibitor
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Faculty Opinions recommendation of Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1025625.322882
◽
2005
◽
Author(s):
James Stivers
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Atm Kinase
◽
Molecule Inhibitor
◽
Hiv 1
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Faculty Opinions recommendation of Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1033159.375732
◽
2006
◽
Author(s):
Berl R Oakley
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Molecule Inhibitor
Download Full-text
Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1066069.520680
◽
2007
◽
Author(s):
Nathanael Gray
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Molecule Inhibitor
◽
Bi 2536
Download Full-text
Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1066069.519039
◽
2007
◽
Author(s):
Tarun Kapoor
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Molecule Inhibitor
◽
Bi 2536
Download Full-text
Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.1283961.751061
◽
2009
◽
Author(s):
Marie-France Carlier
Keyword(s):
Small Molecule
◽
Small Molecule Inhibitor
◽
Actin Assembly
◽
Molecule Inhibitor
◽
Identification And Characterization
Download Full-text
Faculty Opinions recommendation of Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.5059957.4994055
◽
2010
◽
Author(s):
Michael Weber
◽
Daniel G Gioeli
Keyword(s):
Prostate Cancer
◽
Androgen Receptor
◽
Small Molecule
◽
Small Molecule Inhibitor
◽
Amino Terminus
◽
Recurrent Prostate Cancer
◽
Molecule Inhibitor
Download Full-text
Faculty Opinions recommendation of A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.717957380.793461863
◽
2012
◽
Author(s):
Pengbo Zhou
◽
Jeffrey Hannah
Keyword(s):
Multiple Myeloma
◽
Small Molecule
◽
Small Molecule Inhibitor
◽
Myeloma Cells
◽
Molecule Inhibitor
◽
Specific Protease
◽
Ubiquitin Specific Protease
Download Full-text
Faculty Opinions recommendation of Structure-based discovery of BM-957 as a potent small-molecule inhibitor of Bcl-2 and Bcl-xL capable of achieving complete tumor regression.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.717959626.793462957
◽
2012
◽
Author(s):
Mark Searcey
Keyword(s):
Small Molecule
◽
Tumor Regression
◽
Small Molecule Inhibitor
◽
Complete Tumor Regression
◽
Molecule Inhibitor
◽
Complete Tumor
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