Re: Ramakrishnaiah et al.: Reliability of magnetic resonance imaging for the detection of hypopituitarism in children with optic nerve hypoplasia (Ophthalmology 2014;121:387-91)

Ophthalmology ◽  
2014 ◽  
Vol 121 (5) ◽  
pp. e26-e27 ◽  
Author(s):  
Mark Borchert ◽  
Pamela Garcia-Filion ◽  
Cassandra Fink ◽  
Mitchell Geffner ◽  
Marvin Nelson
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Nerve Hypoplasia ◽  
Resonance Imaging

Optic nerve size assessed by magnetic resonance imaging and visual acuity in optic nerve hypoplasia

2021 ◽  
Vol 25 (4) ◽  
pp. e45
Author(s):  
Samantha D. Sagaser ◽  
John C. Benson ◽  
Laurence J. Eckel ◽  
Sasha A. Mansukhani ◽  
Launia White ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Visual Acuity ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Nerve Hypoplasia ◽  
Resonance Imaging

Optic Nerve Hypoplasia: Absence of Posterior Pituitary Bright Signal on Magnetic Resonance Imaging Correlates With Diabetes Insipidus

1996 ◽  
Vol 122 (5) ◽  
pp. 717-723 ◽  
Author(s):  
JEFFREY A. SORKIN ◽  
PATRICIA C. DAVIS ◽  
LILLIAN R. MEACHAM ◽  
JOHN S. PARKS ◽  
ARLENE V. DRACK ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Diabetes Insipidus ◽  
Optic Nerve Hypoplasia ◽  
Posterior Pituitary ◽  
Resonance Imaging

The role of magnetic resonance imaging in diagnosing optic nerve hypoplasia

2013 ◽  
Vol 17 (1) ◽  
pp. e21
Author(s):  
Phoebe D. Lenhart ◽  
Nilesh K. Desai ◽  
Beau B. Bruce ◽  
Amy K. Hutchinson ◽  
Scott R. Lambert
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Nerve Hypoplasia ◽  
Resonance Imaging

scholarly journals The Role of Magnetic Resonance Imaging in Diagnosing Optic Nerve Hypoplasia

2014 ◽  
Vol 158 (6) ◽  
pp. 1164-1171.e2 ◽  
Author(s):  
Phoebe D. Lenhart ◽  
Nilesh K. Desai ◽  
Beau B. Bruce ◽  
Amy K. Hutchinson ◽  
Scott R. Lambert
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Nerve Hypoplasia ◽  
Resonance Imaging

scholarly journals Endocrine Status in Patients with Optic Nerve Hypoplasia: Relationship to Midline Central Nervous System Abnormalities and Appearance of the Hypothalamic-Pituitary Axis on Magnetic Resonance Imaging

2003 ◽  
Vol 88 (11) ◽  
pp. 5281-5286 ◽  
Author(s):  
N. H. Birkebæk ◽  
L. Patel ◽  
N. B. Wright ◽  
J. R. Grigg ◽  
S. Sinha ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Optic Nerve ◽  
Magnetic Resonance ◽  
Optic Nerve Hypoplasia ◽  
Hormone Deficiency ◽  
Pituitary Hormone ◽  
Endocrine Dysfunction ◽  
Resonance Imaging ◽  
Hypothalamic Pituitary Axis ◽  
Group 2

Abstract We here: 1) describe the phenotypic spectrum, including magnetic resonance imaging (MRI) appearances of the pituitary stalk and anterior and posterior pituitary [H-P (hypothalamic-pituitary) axis], in children with optic nerve hypoplasia (ONH) with or without an abnormal septum pellucidum (SP); and 2) define endocrine dysfunction according to the MRI findings. Medical records of 55 children with ONH who had been assessed by ophthalmology and endocrine services were reviewed. All had MRI of the brain and H-P axis. Forty-nine percent of the ONH patients had an abnormal SP on MRI, and 64% had a H-P axis abnormality. Twenty-seven patients (49%) had endocrine dysfunction, and 23 of these had H-P axis abnormality. The frequency of endocrinopathy was higher in patients with an abnormal SP (56%) than a normal SP (39%). Patients were divided into four groups based on SP and H-P axis appearance: 1) both normal; 2) abnormal SP and normal H-P axis; 3) normal SP and abnormal H-P axis; and 4) both abnormal. The frequency of multiple pituitary hormone deficiency was highest (56%) in group 4, lower (35%) in group 3, and even lower (22%) in group 2. Precocious puberty was most common in group 2. None of the patients in group 1 had endocrine dysfunction. Thus, SP and H-P axis appearances on MRI can be used to predict the likely spectrum of endocrinopathy.

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