Re: Datiles et al.: Longitudinal study of age-related cataract using dynamic light scattering: loss of α-crystallin leads to nuclear cataract development (Ophthalmology 2016;123:248-54)

Ophthalmology ◽  
2016 ◽  
Vol 123 (8) ◽  
pp. e47-e48
Author(s):  
Ekaterina Yonova-Doing ◽  
Christopher J. Hammond
Keyword(s):  
Longitudinal Study ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Nuclear Cataract ◽  
Scattering Loss ◽  
Age Related ◽  
Cataract Development

scholarly journals Longitudinal Study of Age-Related Cataract Using Dynamic Light Scattering

Ophthalmology ◽  
2016 ◽  
Vol 123 (2) ◽  
pp. 248-254 ◽  
Author(s):  
Manuel B. Datiles ◽  
Rafat R. Ansari ◽  
Junko Yoshida ◽  
Holly Brown ◽  
Andrea I. Zambrano ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Age Related

scholarly journals Quantitative X-ray tomographic analysis reveals calcium precipitation in cataractogenesis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yuxing Li ◽  
Dilworth Y. Parkinson ◽  
Jun Feng ◽  
Chun-hong Xia ◽  
Xiaohua Gong
Keyword(s):  
Light Scattering ◽  
Dense Matter ◽  
Nuclear Cataract ◽  
Micro Computed Tomography ◽  
Alizarin Red ◽  
Tomographic Images ◽  
X Ray ◽  
Age Related ◽  
Tomographic Analysis ◽  
Calcium Precipitation

AbstractCataracts, named for pathological light scattering in the lens, are known to be associated with increased large protein aggregates, disrupted protein phase separation, and/or osmotic imbalances in lens cells. We have applied synchrotron phase contrast X-ray micro-computed tomography to directly examine an age-related nuclear cataract model in Cx46 knockout (Cx46KO) mice. High-resolution 3D X-ray tomographic images reveal amorphous spots and strip-like dense matter precipitates in lens cores of all examined Cx46KO mice at different ages. The precipitates are predominantly accumulated in the anterior suture regions of lens cores, and they become longer and dense as mice age. Alizarin red staining data confirms the presence of calcium precipitates in lens cores of all Cx46KO mice. This study indicates that the spatial and temporal calcium precipitation is an age-related event associated with age-related nuclear cataract formation in Cx46KO mice, and further suggests that the loss of Cx46 promotes calcium precipitates in the lens core, which is a new mechanism that likely contributes to the pathological light scattering in this age-related cataract model.

Dynamic light scattering from gels in a poor solvent

1978 ◽  
Vol 39 (9) ◽  
pp. 955-960 ◽  
Author(s):  
E. Geissler ◽  
A.M. Hecht
Keyword(s):  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Poor Solvent

DYNAMIC LIGHT SCATTERING IN LC-440 NEMATIC LIQUID CRYSTAL

2014 ◽  
Vol 73 (11) ◽  
pp. 977-983
Author(s):  
A. P. Fedoryako ◽  
A. I. Kocherzhin ◽  
M. P. Kukhtin ◽  
E. I. Chernyakov
Keyword(s):  
Liquid Crystal ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Nematic Liquid Crystal
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