scholarly journals Solitary Retinal Capillary Hemangioma with Nonlipid Exudative Retinal Detachment

Ophthalmology ◽  
2018 ◽  
Vol 125 (2) ◽  
pp. 168 ◽  
Author(s):  
Kuan-Jen Chen ◽  
Nan-Kai Wang ◽  
An-Ning Chao
Keyword(s):  
Retinal Detachment ◽  
Capillary Hemangioma ◽  
Exudative Retinal Detachment ◽  
Retinal Capillary ◽  
Retinal Capillary Hemangioma

Combined brachytherapy and vitreoretinal surgery for a large retinal capillary hemangioma with exudative retinal detachment

2020 ◽  
pp. 112067212094401
Author(s):  
Francesco Barca ◽  
Giulio Vicini ◽  
Cristina Nicolosi ◽  
Giulia Pieretti ◽  
Tomaso Caporossi ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Vitreoretinal Surgery ◽  
Scleral Buckling ◽  
Capillary Hemangioma ◽  
Exudative Retinal Detachment ◽  
Hand Motion ◽  
Retinal Fold ◽  
Retinal Capillary ◽  
Retinal Capillary Hemangioma ◽  
Oncology Unit

Introduction: We report about a large retinal capillary hemangioma (RCH) with exudative retinal detachment and a macular fold, treated with Ruthenium-106 brachytherapy (Ru-106 BT) and scleral buckling surgery, followed by pars plana vitrectomy (PPV), for the removal of macular tractions. Case description: A 17-year-old boy was referred to our Ocular Oncology Unit for a large RCH in the left eye. BCVA was hand motion. The RCH measured 4.9 × 6.85 mm in basal diameters and 4.0 mm in thickness and was located in the mid-peripheral temporal retina. It was surrounded by extensive subretinal exudation, forming an exudative retinal detachment, with a retinal fold that extended from the lesion to the optic disc. We performed Ru-106 BT and at the moment of the plaque removal we placed a radial buckle with the aim to unbend the retinal fold. At 3-months follow-up the exudation decreased, we achieved the opening of the peripheral side of the retinal fold, but the macula was still detached. We decided to perform a lens sparing PPV, macular peeling and air tamponade, to remove the vitreoretinal tractions ab interno and to try to complete the opening of the macular fold. After 1-month BCVA was counting fingers, the retina appeared attached, also in the macular area, but the retinal fold remained partially close in the macular side. After 6 months the tumor was inactivated, the macula remained attached, unfortunately, the macular fold remained partially close. Conclusion: Ru-106 BT and scleral buckling concurrent approach can be an effective treatment modality in selected cases of large RCHs, followed by PPV to remove eventual vitreo-retinal tractions.

scholarly journals A family with Von Hippel-Lindau disease with different presentations

1970 ◽  
Vol 14 (1) ◽  
pp. 17-24
Author(s):  
Ching-lin Wong ◽  
Ming-Yueh Lee ◽  
R. Sunder ◽  
R. Jamalia ◽  
T.V.N. Karunakar ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Laser Photocoagulation ◽  
Case Series ◽  
Capillary Hemangioma ◽  
Exudative Retinal Detachment ◽  
Fundus Examination ◽  
Von Hippel Lindau ◽  
Retinal Capillary ◽  
Von Hippel Lindau Disease ◽  
Retinal Capillary Hemangioma

Objective: To report three cases of Von Hippel-Lindau (VHL) disease from a family with different presentations.Method: Case series.Results: Case 1, a 14-year-old Malay boy with a history of gradual blurring of vision in both eyes presented with sudden deterioration of right vision. Fundus examination revealed bilateral retinal capillary hemangioma with exudative retinal detachment. His right eye underwent combination therapy of laser photocoagulation, cryotherapy, intravitreal anti-VEGF and photodynamic therapy, but failed to improve vision. His left visiondeteriorated and eventually required surgical intervention. Case 2 was the sister of case 1. She was a 17-year-old Malay girl who presented with sudden onset of left eye pain and redness. Diagnosis of left eye rubeotic glaucoma with closed funnel retinal detachment secondary to a huge retinal hemangioma was made. She underwent left eye external drainage of subretinal fluid plus anterior retinal cryopexy. The rubeotic vessel regressed postoperatively and IOP reduced. Case 3 was the eldest sister of case 1; a 19-year-old Malay girl who came for eye screening after two of her siblings were diagnosed with VHL. She was, however, asymptomatic. Fundus examination revealed right retinal capillary hemangioma. She was treated with laser photocoagulation and her condition remained stable. Systemic investigations identified midline cystic masses in the brain, spine and pancreas. Conclusions: This case series highlight different clinical pictures of Von Hippel-Lindau disease. As marked visual loss is a dreadful sequela of VHL, it is important to screen the family members as early detection and management of ocular and systemic lesions save sight and life.

scholarly journals Association of mutations and polymorphic variants of the VHL gene with the clinical characteristics of retinal capillary hemangioma

2019 ◽  
Vol 12 (3) ◽  
pp. 21-29
Author(s):  
V. V. Neroev ◽  
S. V. Saakyan ◽  
A. Yu. Novikova ◽  
M. V. Ryabina ◽  
P. A. Ilyukhin ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Melting Curve ◽  
Polymorphic Marker ◽  
Capillary Hemangioma ◽  
Melting Curve Analysis ◽  
Exudative Retinal Detachment ◽  
Vhl Gene ◽  
Retinal Capillary ◽  
Polymorphic Variants ◽  
Retinal Capillary Hemangioma

Purpose. To study the association of mutations and polymorphic variants of the VHL gene with the clinical characteristics of retinal capillary hemangioma.Material and methods. 29 DNA samples isolated from peripheral blood leukocytes of patients with retinal capillary hemangiomas were tested. The analysis of mutations and polymorphic markers of the VHL gene was carried out by high resolution melting curve analysis.Results. A significant correlation was found between the frequency of tyrosine mutation in the 156th position of the VHL gene and the localization of the capillary hemangioma in the middle periphery of the fundus, the presence of local exudative retinal detachment and fibroglial proliferation in the tumor region (p = 0.02; RR = 1.86). An association was established between arginine mutation frequency in the 200th position of the gene with the presence of cerebellar hemangioblastoma and spinal cord. A statistically significant association of the GA genotype of the polymorphic marker rs779805 of the VHL gene with the localization of capillary hemangioma in the middle periphery of the fundus was established (p = 0.03; RR = 4.8). It has been shown that the carriage of the T allele of the polymorphic marker rs779808 may be associated with the characteristic localization of the tumor at the extreme periphery of the retina in the upper temporal quadrant. A tendency to increasing frequency of occurrence of the AC genotype of the polymorphic marker rs1678607 in patients with hemorrhagic complications of capillary hemangioma, as well as to increasing frequency of the TT genotype of the polymorphic marker rs1642742 in patients with cerebellar hemangioblastomas was determined.Conclusion. Further research involving more clinical material is needed, as our results may be important for early diagnosis of Hippel — Lindau disease, prediction of the onset and clinical course of retinal capillary hemangiomas, as well as of the probability of systemic manifestations of the disease. 

scholarly journals Solitary retinal capillary hemangioma with combined retinal detachment- rare presentation

2019 ◽  
Vol 63 (3) ◽  
pp. 264-267
Author(s):  
S Hemant Trehan ◽  
Ashok Kumar ◽  
Vikas Ambiya ◽  
Gaurav Kapoor ◽  
K Raji ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Capillary Hemangioma ◽  
Rare Presentation ◽  
Retinal Capillary ◽  
Retinal Capillary Hemangioma
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