Label-free immunosensing by long period fiber gratings at the lowest order cladding mode and near turn around point

2021 ◽  
Vol 142 ◽  
pp. 107194
Author(s):  
Tanoy Kumar Dey ◽  
Sara Tombelli ◽  
Palas Biswas ◽  
Ambra Giannetti ◽  
Nandini Basumallick ◽  
...  
Sensors ◽  
2020 ◽  
Vol 20 (3) ◽  
pp. 813 ◽  
Author(s):  
Marta Janczuk-Richter ◽  
Beata Gromadzka ◽  
Łukasz Richter ◽  
Mirosława Panasiuk ◽  
Karolina Zimmer ◽  
...  

Since the norovirus is the main cause of acute gastroenteritis all over the world, its fast detection is crucial in medical diagnostics. In this work, a rapid, sensitive, and selective optical fiber biosensor for the detection of norovirus virus-like particles (VLPs) is reported. The sensor is based on highly sensitive long-period fiber gratings (LPFGs) coated with antibodies against the main coat protein of the norovirus. Several modification methods were verified to obtain reliable immobilization of protein receptors on the LPFG surface. We were able to detect 1 ng/mL norovirus VLPs in a 40-min assay in a label-free manner. Thanks to the application of an optical fiber as the sensor, there is a possibility to increase the user’s safety by separating the measurement point from the signal processing setup. Moreover, our sensor is small and light, and the proposed assay is straightforward. The designed LPFG-based biosensor could be applied in both fast norovirus detection and in vaccine testing.


2020 ◽  
Vol 103 (11-12) ◽  
pp. 46-53
Author(s):  
Yasuhiro Tsutsumi ◽  
Kenta Kitahara ◽  
Masaharu Ohashi ◽  
Hirokazu Kubota ◽  
Yuji Miyoshi ◽  
...  

2012 ◽  
Vol 30 (8) ◽  
pp. 1201-1207 ◽  
Author(s):  
Aleksandra Czapla ◽  
Wojtek J. Bock ◽  
Tomasz R. Wolinski ◽  
Roman Dabrowski ◽  
Edward Nowinowski-Kryszelnicki

2021 ◽  
Author(s):  
Manuel Guterres Soares ◽  
Koken Fukushima ◽  
Bui Quoc Hung ◽  
Koki Nakaya ◽  
Atsushi Wada ◽  
...  

2004 ◽  
Vol 413 (1) ◽  
pp. 399-406 ◽  
Author(s):  
Hak-Rin Kim ◽  
Yonghyun Kim ◽  
Yoonchan Jeong ◽  
Seungin Baek ◽  
Yong Wook Lee ◽  
...  

2017 ◽  
Vol 393 ◽  
pp. 238-243 ◽  
Author(s):  
Yu Liu ◽  
Yuean Mi ◽  
Bofeng Zhu ◽  
Haisu Li ◽  
Wei Jian ◽  
...  

2020 ◽  
Vol 140 (7) ◽  
pp. 682-688
Author(s):  
Yasuhiro Tsutsumi ◽  
Kenta Kitahara ◽  
Masaharu Ohashi ◽  
Hirokazu Kubota ◽  
Yuji Miyoshi ◽  
...  

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