Cell signaling and gene regulation

2012 ◽  
Vol 15 (5) ◽  
pp. 493-495
Author(s):  
Jerzy Paszkowski ◽  
Robert A Martienssen
Keyword(s):  
Gene Regulation ◽  
Cell Signaling

scholarly journals Chemical Reporters and Their Bioorthogonal Reactions for Labeling Protein O-GlcNAcylation

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2411
Author(s):  
Eun Kim
Keyword(s):  
Gene Regulation ◽  
Molecular Biology ◽  
Cell Signaling ◽  
Molecular Tools ◽  
Bioorthogonal Reactions ◽  
Cytoplasmic Proteins ◽  
Mechanistic View ◽  
New Strategies

Protein O-GlcNAcylation is a non-canonical glycosylation of nuclear, mitochondrial, and cytoplasmic proteins with the attachment of a single O-linked β-N-acetyl-glucosamine (O-GlcNAc) moiety. Advances in labeling and identifying O-GlcNAcylated proteins have helped improve the understanding of O-GlcNAcylation at levels that range from basic molecular biology to cell signaling and gene regulation to physiology and disease. This review describes these advances in chemistry involving chemical reporters and their bioorthogonal reactions utilized for detection and construction of O-GlcNAc proteomes in a molecular mechanistic view. This detailed view will help better understand the principles of the chemistries utilized for biology discovery and promote continued efforts in developing new molecular tools and new strategies to further explore protein O-GlcNAcylation.

scholarly journals Transcription factors: Bridge between cell signaling and gene regulation

PROTEOMICS ◽  
2021 ◽  
pp. 2000034
Author(s):  
Paula Weidemüller ◽  
Maksim Kholmatov ◽  
Evangelia Petsalaki ◽  
Judith B. Zaugg
Keyword(s):  
Gene Regulation ◽  
Transcription Factors ◽  
Cell Signaling

Reaction Network Models as a Tool to Study Gene Regulation and Cell Signaling in Development and Diseases

2020 ◽  
pp. 119-159
Author(s):  
Francisco José Pereira Lopes ◽  
Claudio Daniel Tenório de Barros ◽  
Josué Xavier de Carvalho ◽  
Fernando de Magalhães Coutinho Vieira ◽  
Cristiano N. Costa
Keyword(s):  
Gene Regulation ◽  
Cell Signaling ◽  
Reaction Network ◽  
Network Models ◽  
Study Gene Regulation

Cell signaling and gene regulation

2008 ◽  
Vol 11 (5) ◽  
pp. 471-473 ◽  
Author(s):  
Jason W Reed ◽  
Bonnie Bartel
Keyword(s):  
Gene Regulation ◽  
Cell Signaling
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