Upper Gastrointestinal Functional and Motility Disorders in Children

2021 ◽  
Vol 68 (6) ◽  
pp. 1237-1253
Author(s):  
Jonathan Miller ◽  
Julie Khlevner ◽  
Leonel Rodriguez
Keyword(s):  
Motility Disorders ◽  
Upper Gastrointestinal

scholarly journals Prokinetics in the management of upper gastrointestinal motility disorders: an Indian expert opinion review

2021 ◽  
Vol 8 (9) ◽  
pp. 1442
Author(s):  
Ramesh Roop Rai ◽  
V. G. Mohan Prasad
Keyword(s):  
Delayed Gastric Emptying ◽  
Functional Gastrointestinal Disorders ◽  
Primary Concern ◽  
Motility Disorders ◽  
Expert Opinions ◽  
Indian Context ◽  
The Central Nervous System ◽  
Intestinal Motility Disorders ◽  
Upper Gastrointestinal ◽  
Gi Motility

Functional gastrointestinal disorders (FGIDs) are disorders of gut-brain interaction. Nearly 40% of individuals globally suffer from FGIDs and have chronic fluctuating symptoms. Of all GI conditions, 30-45% are referable to intestinal motility disorders. Prokinetics act by different mechanisms and are effective in FGIDs with delayed gastric emptying or postprandial distress. When choosing a prokinetic, safety is the primary concern, particularly with regard to the central nervous system and cardiovascular risk. Here, we review the efficacy and safety of prokinetics in functional GI motility disorders and provide expert opinions for the use of prokinetics to manage upper GI motility disorders in the Indian context. 

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