Resistance of oral squamous cell carcinoma cells to 5-aminolevulinic acid-mediated photodynamic therapy

2017 ◽  
Vol 17 ◽  
pp. A70
Author(s):  
F.C.P. Rosin ◽  
L. Corrêa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Carcinoma Cells

Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma

Head & Neck ◽  
2009 ◽  
Vol 32 (9) ◽  
pp. 1136-1142 ◽  
Author(s):  
Yeon-Hee Moon ◽  
Jong-Hwan Park ◽  
Soo-A Kim ◽  
Jee-Bum Lee ◽  
Sang-Gun Ahn ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Aminolevulinic Acid ◽  
Anticancer Effect

Photocytotoxicity of liposomal zinc phthalocyanine in oral squamous cell carcinoma and pharyngeal carcinoma cells

2020 ◽  
Vol 11 (9) ◽  
pp. 547-556
Author(s):  
Jennifer Cheung ◽  
Diana Furukawa ◽  
Raymond Pandez ◽  
Metin Yıldırım ◽  
Adria Frazier ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma Cells ◽  
Zinc Phthalocyanine ◽  
Pharyngeal Carcinoma ◽  
Liposomal Formulations ◽  
Fadu Cells

Aim: Photodynamic therapy utilizes a light-sensitive molecule that produces reactive oxygen species following irradiation. Photodynamic activities of free Zn phthalocyanine (ZnPc) and its liposomal formulations on human oral squamous cell carcinoma and pharyngeal carcinoma cells were assessed. Materials & methods: ZnPc was incorporated in extruded and nonextruded liposomes composed of palmitoyloleoylphosphatidylglycerol (POPG):palmitoyloleoylphosphatidylcholine (POPC) or POPG:dioleoylphosphatidylethanolamine liposomes and incubated with CAL 27 or FaDu cells. Cell viability was assessed following illumination and further incubation. Results: ZnPc incorporated in extruded POPG:POPC liposomes caused extensive cytotoxicity, while ZnPc in extruded or nonextruded POPG:dioleoylphosphatidylethanolamine liposomes or in multilamellar POPG:POPC liposomes were not effective. Conclusion: Extruded POPG:POPC liposomes are a useful delivery vehicle for ZnPc in photodynamic therapy of oral and pharyngeal cancers.

Thermally activated delayed fluorescent photosensitizer for photodynamic therapy of oral squamous cell carcinoma under low laser intensity

2021 ◽  
Author(s):  
Shiqi Hu ◽  
Bin Huang ◽  
Yumei Pu ◽  
Chengwan Xia ◽  
Qian Zhang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laser Intensity ◽  
Thermally Activated

In this report, a new Thermally activated delayed fluorescent(TADF) molecule [2-(4-triphenylvinyl-phenyl)-anthraquinone (TPE-AQ)] was synthesized. This nanomaterial has satisfactory photostability. In vitro, it was indicated that these TADF nanoparticles (NPs) were...

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