scholarly journals Acute myeloid leukemia complicated by post COVID-19 multi-system inflammatory syndrome-children

2021 ◽  
Author(s):  
Nalla Anuraag Reddy ◽  
Alex Tom ◽  
Harsha Prasada Lashkari
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Inflammatory Syndrome ◽  
Acute Myeloid

scholarly journals A Paraneoplastic Syndrome Characterized by Extremity Swelling with Associated Inflammatory Infiltrate Heralds Aggressive Transformation of Myelodysplastic Syndromes/Myeloproliferative Neoplasms to Acute Myeloid Leukemia: A Case Series

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
James K. Mangan ◽  
Selina M. Luger
Keyword(s):  
Acute Myeloid Leukemia ◽  
Myelodysplastic Syndromes ◽  
Myeloid Leukemia ◽  
Myeloproliferative Neoplasms ◽  
Intensive Therapy ◽  
Myeloproliferative Neoplasm ◽  
Case Series ◽  
Disease Status ◽  
Inflammatory Syndrome ◽  
Acute Myeloid

There has been a long history of reports describing a variety of paraneoplastic phenomena associated with myelodysplastic syndromes, particularly those with autoimmune manifestations. We report here a series of patients with an antecedent myelodysplastic syndrome (MDS) or myeloproliferative neoplasm (MPN) that underwent aggressive transformation to acute myeloid leukemia (AML). In each case, the transformation to AML was preceded by an inflammatory syndrome characterized by unilateral extremity swelling and an associated inflammatory skin infiltrate, as well as other signs of inflammation, including profound hyperferritinemia without evidence of a hemophagocytic syndrome. We suggest that such an inflammatory syndrome may herald aggressive transformation of MDS/MPN to AML. Patients with known MDS/MPN who present with these features may benefit from early bone marrow examination to assess disease status. Early intervention with corticosteroids in select patients may result in improvement or resolution of the symptoms and permit intensive therapy for AML to be delivered.

Author response for "Over expression of brain and acute leukemia, cytoplasmic and ETS-related gene is associated with poor outcome in acute myeloid leukemia"

2020 ◽  
Author(s):  
Hasan, Syed Khizer ◽  
Patkar, Nikhil V. ◽  
Rajamanickam, Deepan ◽  
Gokarn, Anant ◽  
Lucena-Araujo, Antonio R. ◽  
...  
Keyword(s):  
Acute Myeloid Leukemia ◽  
Acute Leukemia ◽  
Myeloid Leukemia ◽  
Author Response ◽  
Related Gene ◽  
Over Expression ◽  
Poor Outcome ◽  
Acute Myeloid
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