Stationary distribution of a stochastic staged progression HIV model with imperfect vaccination

2019 ◽  
Vol 527 ◽  
pp. 121271 ◽  
Author(s):  
Qun Liu ◽  
Daqing Jiang
2020 ◽  
Vol 554 ◽  
pp. 124686
Author(s):  
Qiuyue Li ◽  
Fuzhong Cong ◽  
Tianbao Liu ◽  
Yaoming Zhou

Author(s):  
Qun Liu ◽  
Daqing Jiang

In this paper, we analyze a higher-order stochastically perturbed multigroup staged-progression model for the transmission of HIV with saturated incidence rate. We obtain sufficient conditions for the existence and uniqueness of an ergodic stationary distribution of positive solutions to the system by establishing a suitable stochastic Lyapunov function. In addition, we make up adequate conditions for complete eradication and wiping out the infectious disease. In a biological interpretation, the existence of a stationary distribution implies that the disease will prevail and persist in the long term. Finally, examples and numerical simulations are introduced to validate our theoretical results.


1986 ◽  
Vol 23 (04) ◽  
pp. 1013-1018
Author(s):  
B. G. Quinn ◽  
H. L. MacGillivray

Sufficient conditions are presented for the limiting normality of sequences of discrete random variables possessing unimodal distributions. The conditions are applied to obtain normal approximations directly for the hypergeometric distribution and the stationary distribution of a special birth-death process.


2020 ◽  
Vol 52 (4) ◽  
pp. 1249-1283
Author(s):  
Masatoshi Kimura ◽  
Tetsuya Takine

AbstractThis paper considers ergodic, continuous-time Markov chains $\{X(t)\}_{t \in (\!-\infty,\infty)}$ on $\mathbb{Z}^+=\{0,1,\ldots\}$ . For an arbitrarily fixed $N \in \mathbb{Z}^+$ , we study the conditional stationary distribution $\boldsymbol{\pi}(N)$ given the Markov chain being in $\{0,1,\ldots,N\}$ . We first characterize $\boldsymbol{\pi}(N)$ via systems of linear inequalities and identify simplices that contain $\boldsymbol{\pi}(N)$ , by examining the $(N+1) \times (N+1)$ northwest corner block of the infinitesimal generator $\textbf{\textit{Q}}$ and the subset of the first $N+1$ states whose members are directly reachable from at least one state in $\{N+1,N+2,\ldots\}$ . These results are closely related to the augmented truncation approximation (ATA), and we provide some practical implications for the ATA. Next we consider an extension of the above results, using the $(K+1) \times (K+1)$ ( $K > N$ ) northwest corner block of $\textbf{\textit{Q}}$ and the subset of the first $K+1$ states whose members are directly reachable from at least one state in $\{K+1,K+2,\ldots\}$ . Furthermore, we introduce new state transition structures called (K, N)-skip-free sets, using which we obtain the minimum convex polytope that contains $\boldsymbol{\pi}(N)$ .


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