Poster 462: Efficacy of Intrathecal Baclofen Therapy Compared to Conventional Oral Treatment in Post-Stroke Spasticity: An International Multicenter Randomized Controlled Trial (SISTERS)

PM&R ◽  
2017 ◽  
Vol 9 ◽  
pp. S279-S280
Author(s):  
Michael J. Creamer ◽  
Geoffrey C. Cloud ◽  
Peter PK. Kossmehl ◽  
Michael R. Yochelson ◽  
Gerard E. Francisco ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Oral Treatment ◽  
Intrathecal Baclofen ◽  
Post Stroke ◽  
Randomized Controlled ◽  
Intrathecal Baclofen Therapy ◽  
Multicenter Randomized Controlled Trial ◽  
International Multicenter

Palliative Oxygen Versus Room Air for Refractory Dyspnea (DRAFT)

2018 ◽  
Author(s):  
Jason A. Webb ◽  
Arif H. Kamal
Keyword(s):  
Randomized Controlled Trial ◽  
Oxygen Therapy ◽  
Controlled Trial ◽  
Nasal Cannula ◽  
Patients With Cancer ◽  
Randomized Controlled ◽  
Multicenter Randomized Controlled Trial ◽  
Clinically Significant ◽  
International Multicenter ◽  
Symptomatic Benefit

Palliative oxygen therapy is used for treating dyspnea in patients with cancer and advanced cardiopulmonary diseases, however, small trials have suggested that circulating air may be just as effective. This international, multicenter, randomized controlled trial compared oxygen versus room air delivered by a nasal cannula for relief of dyspnea for patients with any life-limiting illness. Patients were adults >18 years of age, with PaO2 > 7.3kPa, on optimized therapies for their illness, and an expected survival of >1 month. The study demonstrated no clinically significant symptomatic benefit of palliative oxygen versus room air delivered via nasal cannula for seven days in patients with life-limiting illnesses and refractory dyspnea.

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